Engineered annexin A5 variants have impaired cell entry for molecular imaging of apoptosis using pretargeting strategies

Journal of Biological Chemistry

Volumn 286, Issue 3, 2011, Pages 1903-1910

  Ungethüm, Lisette ^a   Kenis, Heidi ^a   Nicolaes, Gerry A ^a   Autin, Ludovic ^b   Stoilova McPhie, Svetla ^c   Reutelingsperger, Chris P M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXINS; APOPTOSIS; APOPTOTIC CELLS; BASIC BUILDING BLOCK; CELL SURFACES; DRIVING FORCES; MOLECULAR IMAGING; PHOSPHATIDYLSERINE; PROTEIN-PROTEIN DOCKING; SALT BRIDGES; SIDE EFFECT; SIGNAL-TO-BACKGROUND RATIO; SITE DIRECTED MUTAGENESIS; STRUCTURAL BIOINFORMATICS; TARGET CELLS; TWO-DIMENSIONAL NETWORKS; WILD TYPES;

AMINO ACIDS; ANTIBIOTICS; BIOINFORMATICS; CELL DEATH; CELL MEMBRANES; OLIGOMERS;

TWO DIMENSIONAL;

ARGININE; ASPARAGINE; ASPARTIC ACID; GLUTAMINE; LIPOCORTIN 5; LYSINE; PHOSPHATIDYLSERINE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; INTERNALIZATION; LEUKEMIA CELL LINE; MOLECULAR DOCKING; MOLECULAR IMAGING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN VARIANT; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STRUCTURAL BIOINFORMATICS; STRUCTURE ACTIVITY RELATION; WILD TYPE;

ANNEXIN A5; APOPTOSIS; CRYSTALLOGRAPHY, X-RAY; HUMANS; JURKAT CELLS; MOLECULAR IMAGING; PHOSPHATIDYLSERINES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, QUATERNARY;

EID: 78751547461     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.163527     Document Type: Article

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