Preliminary in vivo evaluation of a novel 99mTc-Labeled HYNIC-cys-annexin A5 as an apoptosis imaging agent

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 13, 2008, Pages 3794-3798

  Fonge, Humphrey ^a   de Saint Hubert, Marijke ^b   Vunckx, Kathleen ^b   Rattat, Dirk ^a   Nuyts, Johan ^b   Bormans, Guy ^a   Ni, Yicheng ^b   Reutelingsperger, Chris ^c   Verbruggen, Alfons ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Apoptosis; HYNIC cys annexin A5; Imaging; Technetium 99m

Indexed keywords

CONTRAST MEDIUM; HYDRAZINONICOTINAMIDE CYSTEINE ANNEXIN A5 TC 99M;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG DISTRIBUTION; DRUG SCREENING; DRUG STRUCTURE; DRUG UPTAKE; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; RABBIT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY;

ANIMALS; ANNEXIN A5; APOPTOSIS; CHEMISTRY, PHARMACEUTICAL; CYSTEINE; DRUG DESIGN; LIVER; MICE; MODELS, CHEMICAL; MYOCARDIAL INFARCTION; ORGANOTECHNETIUM COMPOUNDS; RABBITS; SULFHYDRYL COMPOUNDS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

MURINAE; MUS; ORYCTOLAGUS CUNICULUS;

EID: 44849095832     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.05.044     Document Type: Article

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