메뉴 건너뛰기




Volumn 9, Issue 9, 2009, Pages 958-967

Translational imaging of apoptosis

Author keywords

Annexin V; Apoptosis; ApoSense; Caspase 3; DEVD; Isatin; PET

Indexed keywords

3 IODOBENZOYL I 124; 4 AMIDOCOUMARIN; 4 IODOBENZOYL I 124; 7 AMINO 4 METHYLCOUMARIN; AMINOLUCIFERIN; APOSENSE MOLECULE; CAMPTOTHECIN; CHEMICAL COMPOUND; COUMARIN DERIVATIVE; DANSYL ML 10; DYE; ETHYLENEDIAMMINE N,N' DIACETATE ANNEXIN 5 TC 99M; FLUORESCEIN ISOTHIOCYANATE; FLUORESCENT DYE; FLUORINE 18; FLUOROURACIL; HYDRAZINONICOTINAMIDE ANNEXIN 5 TC 99M; IODINE 123; IODINE 124; LIPOCORTIN 5; LUCIFERIN; ML 10 F 18; ML 10 H 3; N,N' DI DANSYL CYSTINE; NST 732; RADIOISOTOPE; SMALL MOLECULE COMPOUND; SODIUM IODIDE I 124; TECHNETIUM 99M; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 73449095414     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152009789377709     Document Type: Review
Times cited : (15)

References (60)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr, J.F.; Wyllie, A.H.; Currie, A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer, 1972, 26, 239-57.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 2
    • 0036463649 scopus 로고    scopus 로고
    • Apoptosis-based therapies
    • Reed, J.C. Apoptosis-based therapies. Nat. Rev. Drug Disc., 2002, 1, 111-121.
    • (2002) Nat. Rev. Drug Disc , vol.1 , pp. 111-121
    • Reed, J.C.1
  • 3
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D.; Weinberg, R.A. The hallmarks of cancer. Cell, 2000, 100, 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 46749092088 scopus 로고    scopus 로고
    • In vivo detection of apoptosis
    • Blankenberg, F.G. In vivo detection of apoptosis. J. Nucl. Med., 2008, 49 (Suppl 2), 81S-95S.
    • (2008) J. Nucl. Med , vol.49 , Issue.SUPPL. 2
    • Blankenberg, F.G.1
  • 5
    • 53749104279 scopus 로고    scopus 로고
    • Imaging of apoptosis
    • Tait, J.F. Imaging of apoptosis. J. Nucl. Med., 2008, 49, 1573-6.
    • (2008) J. Nucl. Med , vol.49 , pp. 1573-1576
    • Tait, J.F.1
  • 6
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin, S.J.; Reutelingsperger, C.P.; McGahon, A.J.; Rader, J.A.; van Schie, R.C.; LaFace, D.M.; Green, D.R. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med., 1995, 182, 1545-56.
    • (1995) J. Exp. Med , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutelingsperger, C.P.2    McGahon, A.J.3    Rader, J.A.4    van Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 15
    • 43549116086 scopus 로고    scopus 로고
    • Extracellular annexin A5: Functions of phosphatidyl-serine-binding and two-dimensional crystallization
    • van Genderen, H.O.; Kenis, H.; Hofstra, L.; Narula, J.; Reutelingsperger, C.P. Extracellular annexin A5: functions of phosphatidyl-serine-binding and two-dimensional crystallization. Biochim. Biophys. Acta, 2008, 1783, 953-63.
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 953-963
    • van Genderen, H.O.1    Kenis, H.2    Hofstra, L.3    Narula, J.4    Reutelingsperger, C.P.5
  • 18
    • 73449091938 scopus 로고    scopus 로고
    • Ziv, I.; Shirvan, A. Perturbed membrane-binding compounds and methods of using the same. WO 2005/067388, 2005.
    • Ziv, I.; Shirvan, A. Perturbed membrane-binding compounds and methods of using the same. WO 2005/067388, 2005.
  • 19
  • 20
    • 60649115423 scopus 로고    scopus 로고
    • Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis
    • Grimberg, H.; Levin, G.; Shirvan, A.; Cohen, A.; Yogev-Falach, M.; Reshef, A.; Ziv, I. Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. Apoptosis, 2009, 14, 257-267.
    • (2009) Apoptosis , vol.14 , pp. 257-267
    • Grimberg, H.1    Levin, G.2    Shirvan, A.3    Cohen, A.4    Yogev-Falach, M.5    Reshef, A.6    Ziv, I.7
  • 23
    • 67649109027 scopus 로고    scopus 로고
    • From the Gla domain to a novel small-molecule detector of apoptosis
    • Cohen, A.; Shirvan, A.; Levin, G.; Grimberg, H.; Reshef, A.; Ziv, I. From the Gla domain to a novel small-molecule detector of apoptosis. Cell Res., 2009, 19(5), 625-627.
    • (2009) Cell Res , vol.19 , Issue.5 , pp. 625-627
    • Cohen, A.1    Shirvan, A.2    Levin, G.3    Grimberg, H.4    Reshef, A.5    Ziv, I.6
  • 24
    • 0345120940 scopus 로고    scopus 로고
    • Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
    • Scaduto, R.C., Jr.; Grotyohann, L.W. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophys. J., 1999, 76, 469-77.
    • (1999) Biophys. J , vol.76 , pp. 469-477
    • Scaduto Jr., R.C.1    Grotyohann, L.W.2
  • 25
    • 3543092021 scopus 로고    scopus 로고
    • Pathways of apoptotic and non-apoptotic cell death in tumour cells
    • Okada, H.; Mak, T.W. Pathways of apoptotic and non-apoptotic cell death in tumour cells. Nat. Rev. Cancer, 2004, 4, 592-603.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 592-603
    • Okada, H.1    Mak, T.W.2
  • 27
    • 0347601880 scopus 로고    scopus 로고
    • A decade of caspases
    • Degterev, A.; Boyce, M.; Yuan, J. A decade of caspases. Oncogene, 2003, 22, 8543-8567.
    • (2003) Oncogene , vol.22 , pp. 8543-8567
    • Degterev, A.1    Boyce, M.2    Yuan, J.3
  • 29
    • 0032885388 scopus 로고    scopus 로고
    • Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
    • Earnshaw, W.C.; Martins, L.M.; Kaufmann, S.C. Mammalian caspases: structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem., 1999, 68, 383-424.
    • (1999) Annu. Rev. Biochem , vol.68 , pp. 383-424
    • Earnshaw, W.C.1    Martins, L.M.2    Kaufmann, S.C.3
  • 30
    • 2442505378 scopus 로고    scopus 로고
    • Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway
    • Woo, E.-J.; Kim, Y.-G.; Han, W.-D.; Shin, S.; Robinson, H.; Park, S.-Y.; Oh, B.-H. Structural mechanism for inactivation and activation of CAD/DFF40 in the apoptotic pathway. Mol. Cell, 2004, 14, 531-539.
    • (2004) Mol. Cell , vol.14 , pp. 531-539
    • Woo, E.-J.1    Kim, Y.-G.2    Han, W.-D.3    Shin, S.4    Robinson, H.5    Park, S.-Y.6    Oh, B.-H.7
  • 33
    • 0030002801 scopus 로고    scopus 로고
    • Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (SZ-VAD-FMK) inhibits apoptosis by blocking the processing of CPP32
    • Slee, E.A.; Zhu, H.; Chow, S.C.; MacFarlane, M.; Nicholson, D.W.; Cohen, G.M. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (SZ-VAD-FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem. J., 1996, 315, 21-24.
    • (1996) Biochem. J , vol.315 , pp. 21-24
    • Slee, E.A.1    Zhu, H.2    Chow, S.C.3    MacFarlane, M.4    Nicholson, D.W.5    Cohen, G.M.6
  • 34
    • 0033571424 scopus 로고    scopus 로고
    • Fluorescent molecular probes V: A sensitive caspase-3 substrate for fluorometric assays
    • Liu, J.; Bhalgat, M.; Zhang, C.; Diwu, Z.; Hoyland, B.; Klaubert, D.H. Fluorescent molecular probes V: a sensitive caspase-3 substrate for fluorometric assays. Bioorg. Med. Chem. Lett., 1999, 9, 3231-6.
    • (1999) Bioorg. Med. Chem. Lett , vol.9 , pp. 3231-3236
    • Liu, J.1    Bhalgat, M.2    Zhang, C.3    Diwu, Z.4    Hoyland, B.5    Klaubert, D.H.6
  • 35
    • 0035825367 scopus 로고    scopus 로고
    • Design and synthesis of rhodamine 110 derivative and caspase-3 substrate for enzyme and cell-based fluorescent assay
    • Cai, S.X.; Zhang, H.-Z.; Guastella, J.; Drewe, J.; Yang, W.; Weber, E. Design and synthesis of rhodamine 110 derivative and caspase-3 substrate for enzyme and cell-based fluorescent assay. Bioorg. Med. Chem. Lett., 2001, 11, 39-42.
    • (2001) Bioorg. Med. Chem. Lett , vol.11 , pp. 39-42
    • Cai, S.X.1    Zhang, H.-Z.2    Guastella, J.3    Drewe, J.4    Yang, W.5    Weber, E.6
  • 36
    • 17144388653 scopus 로고    scopus 로고
    • N-DEVD-N′- morpholinecarbonylrhodamine 110: Novel caspase-3 fluorogenic substrates for cell-based apoptosis assay
    • Wang, Z.Q.; Liao, J.; Diwu, Z. N-DEVD-N′- morpholinecarbonylrhodamine 110: novel caspase-3 fluorogenic substrates for cell-based apoptosis assay. Bioorg. Med. Chem. Lett., 2005, 15, 2335-8.
    • (2005) Bioorg. Med. Chem. Lett , vol.15 , pp. 2335-2338
    • Wang, Z.Q.1    Liao, J.2    Diwu, Z.3
  • 38
    • 49649134367 scopus 로고
    • Studies on firefly bioluminescence-1
    • Suzuki, N.; Sato, M.; Okada, K.; Goto, T. Studies on firefly bioluminescence-1. Tetrahedron, 1972, 28, 4065-4074.
    • (1972) Tetrahedron , vol.28 , pp. 4065-4074
    • Suzuki, N.1    Sato, M.2    Okada, K.3    Goto, T.4
  • 39
    • 23944469298 scopus 로고    scopus 로고
    • Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
    • Bullok, K.; Piwnica-Worms, D. Synthesis and characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. J. Med. Chem., 2005, 48, 5404-5407.
    • (2005) J. Med. Chem , vol.48 , pp. 5404-5407
    • Bullok, K.1    Piwnica-Worms, D.2
  • 40
    • 34047219123 scopus 로고    scopus 로고
    • Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis
    • Bullok, K.E.; Maxwell, D.; Kesarwala, A.H.; Gammon, S.; Prior, J.L.; Snow, M.; Stanley, S.; Piwnica-Worms, D. Biochemical and in vivo characterization of a small, membrane-permeant, caspase-activatable far-red fluorescent peptide for imaging apoptosis. Biochemistry, 2007, 46, 4055-4065.
    • (2007) Biochemistry , vol.46 , pp. 4055-4065
    • Bullok, K.E.1    Maxwell, D.2    Kesarwala, A.H.3    Gammon, S.4    Prior, J.L.5    Snow, M.6    Stanley, S.7    Piwnica-Worms, D.8
  • 41
    • 33745648315 scopus 로고    scopus 로고
    • Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ
    • Stefflova, K.; Chen, J.; Marotta, D.; Li, H.; Zheng, G. Photodynamic therapy agent with a built-in apoptosis sensor for evaluating its own therapeutic outcome in situ. J. Med. Chem., 2006, 49, 3850-3856.
    • (2006) J. Med. Chem , vol.49 , pp. 3850-3856
    • Stefflova, K.1    Chen, J.2    Marotta, D.3    Li, H.4    Zheng, G.5
  • 42
    • 0034802796 scopus 로고    scopus 로고
    • Investigation of a potential scintigraphic marker of apoptosis: Radioiodinated Z-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone
    • Haberkorn, U.; Kinscherf, R.; Krammer, P.H.; Mier, W.; Eisenhut, M. Investigation of a potential scintigraphic marker of apoptosis: radioiodinated Z-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone. Nucl. Med. Biol., 2001, 28, 793-798.
    • (2001) Nucl. Med. Biol , vol.28 , pp. 793-798
    • Haberkorn, U.1    Kinscherf, R.2    Krammer, P.H.3    Mier, W.4    Eisenhut, M.5
  • 45
    • 0034717269 scopus 로고    scopus 로고
    • Lee, D.; Long, S.A.; Adams, J.L.; Chan, G.; Vaidya, K.S.; Francis, T.A.; Kikly, K.; Winkler, J.D.; Sung, C.; Debouck, C.; Richardson, S.; Levy, M.A.; DeWolf, W.E.; Keller, P.M.; Tomaszek, T.; Head, M.S.; Ryan, M.D.; Haltiwanger, R.C.; Liang, P.; Janson, C.A.; McDevitt, P.J.; Johanson, K.; Concha, N.O.; Chan, W.; Abdel-Meguid, S.S.; Badger, A.M.; Lark, M.W.; Nadeau, D.P.; Suva, L.J.; Gowen, M.; Nuttall, M.E. Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality. J. Biol. Chem., 2000, 275, 16007-16014.
    • Lee, D.; Long, S.A.; Adams, J.L.; Chan, G.; Vaidya, K.S.; Francis, T.A.; Kikly, K.; Winkler, J.D.; Sung, C.; Debouck, C.; Richardson, S.; Levy, M.A.; DeWolf, W.E.; Keller, P.M.; Tomaszek, T.; Head, M.S.; Ryan, M.D.; Haltiwanger, R.C.; Liang, P.; Janson, C.A.; McDevitt, P.J.; Johanson, K.; Concha, N.O.; Chan, W.; Abdel-Meguid, S.S.; Badger, A.M.; Lark, M.W.; Nadeau, D.P.; Suva, L.J.; Gowen, M.; Nuttall, M.E. Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality. J. Biol. Chem., 2000, 275, 16007-16014.
  • 46
    • 28144443339 scopus 로고    scopus 로고
    • N-Benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: Synthesis, in vitro activity, and molecular modeling studies
    • Chu, W.; Zhang, J.; Zeng, C.; Rothfuss, J.; Tu, Z.; Chu, Y.; Reichert, D.E.; Welch, M.J.; Mach, R.H. N-Benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: Synthesis, in vitro activity, and molecular modeling studies. J. Med. Chem., 2005, 48, 7637-7647.
    • (2005) J. Med. Chem , vol.48 , pp. 7637-7647
    • Chu, W.1    Zhang, J.2    Zeng, C.3    Rothfuss, J.4    Tu, Z.5    Chu, Y.6    Reichert, D.E.7    Welch, M.J.8    Mach, R.H.9
  • 50
    • 34547593361 scopus 로고    scopus 로고
    • Isatin sulfonamide analogs containing a michael addition acceptor: A new class of caspase 3/7 inhibitors
    • Chu, W.; Rothfuss, J.; d'Avignon, A.; Zeng, C.; Zhou, D.; Hotchkiss, R.S.; Mach, R.H. Isatin sulfonamide analogs containing a michael addition acceptor: a new class of caspase 3/7 inhibitors. J. Med. Chem., 2007, 50, 3751-3755.
    • (2007) J. Med. Chem , vol.50 , pp. 3751-3755
    • Chu, W.1    Rothfuss, J.2    d'Avignon, A.3    Zeng, C.4    Zhou, D.5    Hotchkiss, R.S.6    Mach, R.H.7
  • 51
    • 54349096337 scopus 로고    scopus 로고
    • In vivo imaging of apoptosis
    • Blankenberg, F.G. In vivo imaging of apoptosis. Cancer. Biol. Ther., 2008, 7, 1525-32.
    • (2008) Cancer. Biol. Ther , vol.7 , pp. 1525-1532
    • Blankenberg, F.G.1
  • 53
    • 1242293893 scopus 로고    scopus 로고
    • Dipeptidyl aspartyl fluoromethylketones as potent caspase-3 inhibitors: SAR of the P2 amino acid
    • Wang, Y.; Huang, J.C.; Zhou, Z.L.; Yang, W.; Guastella, J.; Drewe, J.; Cai, S.X. Dipeptidyl aspartyl fluoromethylketones as potent caspase-3 inhibitors: SAR of the P2 amino acid. Bioorg. Med. Chem. Lett., 2004, 14, 1269-72.
    • (2004) Bioorg. Med. Chem. Lett , vol.14 , pp. 1269-1272
    • Wang, Y.1    Huang, J.C.2    Zhou, Z.L.3    Yang, W.4    Guastella, J.5    Drewe, J.6    Cai, S.X.7
  • 55
    • 34249719936 scopus 로고    scopus 로고
    • The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2- methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent
    • Faust, A.; Wagner, S.; Law, M.P.; Hermann, S.; Schnockel, U.; Keul, P.; Schober, O.; Schafers, M.; Levkau, B.; Kopka, K. The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2- methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent. Q. J. Nucl. Med. Mol. Imaging, 2007, 51, 67-73.
    • (2007) Q. J. Nucl. Med. Mol. Imaging , vol.51 , pp. 67-73
    • Faust, A.1    Wagner, S.2    Law, M.P.3    Hermann, S.4    Schnockel, U.5    Keul, P.6    Schober, O.7    Schafers, M.8    Levkau, B.9    Kopka, K.10
  • 56
    • 20144384669 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8- (morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors
    • Kravchenko, D.V.; Kuzovkova, Y.A.; Kysil, V.M.; Tkachenko, S.E.; Maliarchouk, S.; Okun, I.M.; Balakin, K.V.; Ivachtchenko, A.V. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8- (morpholine-4-sulfonyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. J. Med. Chem., 2005, 48, 3680-3.
    • (2005) J. Med. Chem , vol.48 , pp. 3680-3683
    • Kravchenko, D.V.1    Kuzovkova, Y.A.2    Kysil, V.M.3    Tkachenko, S.E.4    Maliarchouk, S.5    Okun, I.M.6    Balakin, K.V.7    Ivachtchenko, A.V.8
  • 58
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse, P.; Arbuck, S.G.; Eisenhauer, E.A.; Wanders, J.; Kaplan, R.S.; Rubinstein, L.; Verweij, J.; Van Glabbeke, M.; van Oosterom, A.T.; Christian, M.C.; Gwyther, S.G. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J. Natl. Cancer Inst., 2000, 92, 205-16.
    • (2000) J. Natl. Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.G.2    Eisenhauer, E.A.3    Wanders, J.4    Kaplan, R.S.5    Rubinstein, L.6    Verweij, J.7    Van Glabbeke, M.8    van Oosterom, A.T.9    Christian, M.C.10    Gwyther, S.G.11
  • 59
    • 33646357786 scopus 로고    scopus 로고
    • Measuring response in a post-RECIST world: From black and white to shades of grey
    • Michaelis, L.C.; Ratain, M.J. Measuring response in a post-RECIST world: from black and white to shades of grey. Nat. Rev. Cancer, 2006, 6, 409-14.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 409-414
    • Michaelis, L.C.1    Ratain, M.J.2
  • 60
    • 66149139452 scopus 로고    scopus 로고
    • From RECIST to PERCIST: Evolving considerations for PET response criteria in solid tumors
    • Wahl, R.L.; Jacene, H.; Kasamon, Y.; Lodge, M.A. From RECIST to PERCIST: evolving considerations for PET response criteria in solid tumors. J. Nucl. Med., 2009, 50, S122-S150.
    • (2009) J. Nucl. Med , vol.50
    • Wahl, R.L.1    Jacene, H.2    Kasamon, Y.3    Lodge, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.