Evaluation of a 99mTc-labeled annexina5 variant for non-invasive spect imaging of cell death in liver, spleen and prostate

Pharmaceutical Research

Volumn 26, Issue 12, 2009, Pages 2647-2656

  Greupink, Rick ^a   Sio, Charles F ^b   Ederveen, Antwan ^a   Orsel, Joke ^b  

^a MERCK RESEARCH LABORATORIES   (United States)

^b PHILIPS RESEARCH LABORATORIES   (Netherlands)

Author keywords

AnnexinA5; Apoptosis; Cell death; Molecular imaging; SPECT CT

Indexed keywords

CYCLOHEXIMIDE; HYDRAZINONICOTINAMIDE CYSTEINE LIPOCORTIN A5 TECHNETIUM TC 99M; LIPOCORTIN 5; PHOSPHATIDYLSERINE; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; CYSTEINE; DIAGNOSTIC AGENT; TECHNETIUM COMPLEX;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CASTRATION; CELL DEATH; COMPARTMENT MODEL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG SYNTHESIS; HISTOPATHOLOGY; ISOTOPE LABELING; LIVER; MALE; MOLECULAR IMAGING; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROSTATE EPITHELIUM; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPLEEN; ANIMAL; CHEMISTRY; EVALUATION; PATHOLOGY; PROSTATE; SCINTISCANNING; WISTAR RAT;

ANIMALS; ANNEXIN A5; CELL DEATH; CYSTEINE; LIVER; MALE; ORGANOTECHNETIUM COMPOUNDS; PROSTATE; RATS; RATS, WISTAR; SPLEEN;

EID: 70449133429     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9981-4     Document Type: Article

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