Necrostatin decreases oxidative damage, inflammation, and injury after neonatal HI

Journal of Cerebral Blood Flow and Metabolism

Volumn 31, Issue 1, 2011, Pages 178-189

  Northington, Frances J ^a   Chavez Valdez, Raul ^a,b   Graham, Ernest M ^a   Razdan, Sheila ^a   Gauda, Estelle B ^a   Martin, Lee J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

apoptosis necrosis cell death continuum; cytokines; delayed neurodegeneration; NFkB; programmed necrosis; receptor interacting protein (RIP)

Indexed keywords

5 (1H INDOL 3 YLMETHYL)(2 THIO 3 METHYL)HYDANTOIN; CYTOKINE; FLICE INHIBITORY PROTEIN; GENE PRODUCT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12P35; INTERLEUKIN 1BETA; INTERLEUKIN 6; METHYL BETA CYCLODEXTRIN; NECROSTATIN; NECROSTATIN 1; NEUROPROTECTIVE AGENT; PROTEIN; REACTIVE OXYGEN METABOLITE; RECEPTOR INTERACTING PROTEIN 1; RECEPTOR INTERACTING PROTEIN 1 KINASE; RECEPTOR INTERACTING PROTEIN 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVITY; ENZYME ASSAY; GENE EXPRESSION; HISTOLOGY; IMMUNOBLOTTING; INFLAMMATION; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; OXIDATION; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE NECROSIS;

ANIMALS; ANIMALS, NEWBORN; BLOTTING, WESTERN; CASPASES; CELL DEATH; ENCEPHALITIS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HYPOXIA-ISCHEMIA, BRAIN; IMAGE PROCESSING, COMPUTER-ASSISTED; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INDOLES; MICE; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PROTEIN KINASE INHIBITORS; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTOR RELA;

EID: 78650911946     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2010.72     Document Type: Article

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