Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 34, Issue 12, 2007, Pages 2057-2065

  Madar, Igal ^a   Ravert, Hayden ^a   Nelkin, Barry ^b   Abro, Masroor ^a   Pomper, Martin ^a   Dannals, Robert ^a   Frost, James J ^a  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

18F FBnTP; 3H TPP; Apoptosis; Membrane potential; PET; Phosphonium

Indexed keywords

CATION; FLUOROBENZYLTRIPHENYLPHOSPHONIUM F 18; RADIOPHARMACEUTICAL AGENT; STAUROSPORINE; TETRAPHENYLPHOSPHONIUM H 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CORRELATION COEFFICIENT; DIAGNOSTIC PROCEDURE; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG UPTAKE; HUMAN; HUMAN CELL; KINETICS; LUNG CARCINOMA; MEMBRANE DEPOLARIZATION; MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; SENSOR;

ANIMALS; CARCINOMA, SMALL CELL; CELL LINE, TUMOR; CELL MEMBRANE; HUMANS; MEMBRANE POTENTIALS; METABOLIC CLEARANCE RATE; MICE; ORGAN SPECIFICITY; ORGANOPHOSPHORUS COMPOUNDS; TISSUE DISTRIBUTION;

EID: 36749075506     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-007-0500-8     Document Type: Article

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