Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

Nature Protocols

Volumn 4, Issue 12, 2009, Pages 1798-1806

  Debacq Chainiaux, Florence ^a   Erusalimsky, Jorge D ^b   Campisi, Judith ^c,d   Toussaint, Olivier ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b CARDIFF METROPOLITAN UNIVERSITY   (United Kingdom)

^c BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; FLUORESCENT DYE;

ALKALINIZATION; ARTICLE; CELL AGING; CELL PROLIFERATION; CELL STRESS; CYTOCHEMISTRY; ENZYME ACTIVITY; FETUS; HISTOCHEMISTRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO STUDY; LYSOSOME; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY ANALYSIS; TISSUE SECTION;

BETA-GALACTOSIDASE; BIOLOGICAL MARKERS; CELL AGING; FLUORESCEINS; GALACTOSIDES; HISTOCYTOCHEMISTRY; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MICROSCOPY, FLUORESCENCE;

MAMMALIA;

EID: 74949127989     PISSN: 17542189     EISSN: 17502799     Source Type: Journal    
DOI: 10.1038/nprot.2009.191     Document Type: Article

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