Synthesis and preliminary evaluation of mono-[123I]iodohypericin monocarboxylic acid as a necrosis avid imaging agent

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 14, 2007, Pages 4001-4005

  Fonge, Humphrey ^a   Jin, Lixin ^a   Wang, Huaijun ^b   Ni, Yicheng ^b   Bormans, Guy ^a   Verbruggen, Alfons ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Autoradiography; Mono 123I iodohypericin monocarboxylic acid; Necrosis avidity

Indexed keywords

ALCOHOL; HYPERICIN; IODINE 123; IODOHYPERICIN MONOCARBOXYLIC ACID I 123; TRACER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG SCREENING; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; LIVER NECROSIS; MALE; MOUSE; NONHUMAN; RAT;

ANIMALS; AUTORADIOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IODINE RADIOISOTOPES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; NECROSIS; PERYLENE; RATS;

MUS; RATTUS;

EID: 34250377800     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.04.083     Document Type: Article

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