High throughput ratio imaging to profile caspase activity: Potential application in multiparameter high content apoptosis analysis and drug screening

PLoS ONE

Volumn 6, Issue 5, 2011, Pages

  Joseph, Jeena ^a   Seervi, Mahendra ^a   Sobhan, Praveen K ^a   Retnabai, Santhoshkumar Thankayyan ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DICHLOROBENZIMIDAZOLE RIBOSIDE; ALVESPIMYCIN; ANISOMYCIN; APICIDIN; APIGENIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CAMPTOTHECIN; CASPASE; CISPLATIN; CYCLOHEXIMIDE; CYCLOPHOSPHAMIDE; DACTINOMYCIN; FLUOROURACIL; GINGEROL; GOSSYPOL; INDOMETACIN; LACTACYSTIN; MEVINOLIN; MIMOSINE; MITOXANTRONE; MONASTROL; NOVOBIOCIN; RADICICOL; STAUROSPORINE; SULINDAC; TANESPIMYCIN; TRICHOSTATIN A; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; TUNICAMYCIN; UNINDEXED DRUG; ANTINEOPLASTIC AGENT; CASPASE 9; DEVDASE; PEPTIDE HYDROLASE;

APOPTOSIS; ARTICLE; BIOSENSOR; CANCER CELL CULTURE; CANCER RESISTANCE; CELL DEATH; CELL FATE; CELL STRAIN MCF 7; CELL SURVIVAL; CONTROLLED STUDY; DRUG RESPONSE; DRUG SCREENING; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; HELA CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR IMAGING; CHROMATIN; DRUG EFFECT; DRUG RESISTANCE; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; KINETICS; METABOLISM; METHODOLOGY; MOLECULAR PROBE; REPRODUCIBILITY; THREE DIMENSIONAL IMAGING; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASE 9; CASPASES; CELL LINE, TUMOR; CHROMATIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; IMAGING, THREE-DIMENSIONAL; KINETICS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MOLECULAR PROBES; PEPTIDE HYDROLASES; REPRODUCIBILITY OF RESULTS; TRANSFECTION;

EID: 79957619035     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0020114     Document Type: Article

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