메뉴 건너뛰기




Volumn 1808, Issue 11, 2011, Pages 2638-2645

In search of a novel target - Phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy

Author keywords

Cancer plasma membrane; Peptide target; Phosphatidylserine exposure; Tumor marker

Indexed keywords

ANTINEOPLASTIC AGENT; ONOSMA PANICULATUM EXTRACT; PHOSPHATIDYLSERINE; PLANT EXTRACT; UNCLASSIFIED DRUG;

EID: 80255124055     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2011.07.026     Document Type: Article
Times cited : (272)

References (45)
  • 1
    • 8744280019 scopus 로고    scopus 로고
    • The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies
    • DOI 10.1016/j.clon.2004.06.007, PII S0936655504002225
    • G. Morgan, R. Ward, and M. Barton The contribution of cytotoxic chemotherapy to 5-year survival in adult malignancies Clin. Oncol. (R. Coll. Radiol.) 16 2004 549 560 (Pubitemid 39517664)
    • (2004) Clinical Oncology , vol.16 , Issue.8 , pp. 549-560
    • Morgan, G.W.1    Ward, R.2    Barton, M.3
  • 2
    • 0029852111 scopus 로고    scopus 로고
    • Regulatory mechanisms in maintenance and modulation of transmembrane lipid asymmetry: Pathophysiological implications
    • E.M. Bevers, P. Comfurius, and R.F. Zwaal Regulatory mechanisms in maintenance and modulation of transmembrane lipid asymmetry: pathophysiological implications Lupus 5 1996 480 487 (Pubitemid 26354072)
    • (1996) Lupus , vol.5 , Issue.5 , pp. 480-487
    • Bevers, E.M.1    Comfurius, P.2    Zwaal, R.F.A.3
  • 4
    • 18544381354 scopus 로고    scopus 로고
    • Surface exposure of phosphatidylserine in pathological cells
    • DOI 10.1007/s00018-005-4527-3
    • R.F. Zwaal, P. Comfurius, and E.M. Bevers Surface exposure of phosphatidylserine in pathological cells Cell Mol. Life Sci. 62 2005 971 988 (Pubitemid 40655614)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.9 , pp. 971-988
    • Zwaal, R.F.A.1    Comfurius, P.2    Bevers, E.M.3
  • 5
    • 0031043059 scopus 로고    scopus 로고
    • Pathophysiologic implications of membrane phospholipid asymmetry in blood cells
    • R.F. Zwaal, and A.J. Schroit Pathophysiologic implications of membrane phospholipid asymmetry in blood cells Blood 89 1997 1121 1132 (Pubitemid 27079974)
    • (1997) Blood , vol.89 , Issue.4 , pp. 1121-1132
    • Zwaal, R.F.A.1    Schroit, A.J.2
  • 6
    • 0026508561 scopus 로고
    • Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
    • V.A. Fadok, D.R. Voelker, P.A. Campbell, J.J. Cohen, D.L. Bratton, and P.M. Henson Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages J. Immunol. 148 1992 2207 2216
    • (1992) J. Immunol. , vol.148 , pp. 2207-2216
    • Fadok, V.A.1    Voelker, D.R.2    Campbell, P.A.3    Cohen, J.J.4    Bratton, D.L.5    Henson, P.M.6
  • 7
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phophatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Ab1
    • S. Martin, C.P. Reutelingsperger, A. McGahon, J. Rader, R. van Schie, D. La Face, and D.R. Green Early redistribution of plasma membrane phophatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Ab1 J. Exp. Med. 182 1995 1545 1556
    • (1995) J. Exp. Med. , vol.182 , pp. 1545-1556
    • Martin, S.1    Reutelingsperger, C.P.2    McGahon, A.3    Rader, J.4    Van Schie, R.5    La Face, D.6    Green, D.R.7
  • 9
    • 0345112372 scopus 로고
    • Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: Quantitative assessment of outer-leaflet lipid by prothrombinase complex formation
    • DOI 10.1073/pnas.86.9.3184
    • J. Connor, C. Bucana, I.J. Fidler, and A.J. Schroit Differentiation- dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation Proc. Natl. Acad. Sci. U.S.A. 86 1989 3184 3188 (Pubitemid 19129581)
    • (1989) Proceedings of the National Academy of Sciences of the United States of America , vol.86 , Issue.9 , pp. 3184-3188
    • Connor, J.1    Bucana, C.2    Fidler, I.J.3    Schroit, A.J.4
  • 10
    • 27544478703 scopus 로고    scopus 로고
    • The NK-lysin derived peptide NK-2 preferentially kills cancer cells with increased surface levels of negatively charged phosphatidylserine
    • DOI 10.1016/j.febslet.2005.09.084, PII S0014579305012081
    • H. Schroder-Borm, R. Bakalova, and J. Andrä The NK-lysin derived peptide NK-2 preferentially kills cancer cells with increased surface levels of negatively charged phosphatidylserine FEBS Lett. 579 2005 6128 6134 (Pubitemid 41546259)
    • (2005) FEBS Letters , vol.579 , Issue.27 , pp. 6128-6134
    • Schroder-Borm, H.1    Bakalova, R.2    Andra, J.3
  • 11
    • 0025743796 scopus 로고
    • Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes
    • T. Utsugi, A.J. Schroit, J. Connor, C.D. Bucana, and I.J. Fidler Elevated expression of phosphatidylserine in the outer membrane leaflet of human tumor cells and recognition by activated human blood monocytes Cancer Res. 51 1991 3062 3066
    • (1991) Cancer Res. , vol.51 , pp. 3062-3066
    • Utsugi, T.1    Schroit, A.J.2    Connor, J.3    Bucana, C.D.4    Fidler, I.J.5
  • 12
    • 0346256782 scopus 로고    scopus 로고
    • Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)
    • DOI 10.1042/BJ20030886
    • H. Woehlecke, A. Pohl, N. Alder-Baerens, H. Lage, and A. Herrmann Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2) Biochem. J. 376 2003 489 495 (Pubitemid 38010534)
    • (2003) Biochemical Journal , vol.376 , Issue.2 , pp. 489-495
    • Woehlecke, H.1    Pohl, A.2    Alder-Baerens, N.3    Lage, H.4    Herrmann, A.5
  • 13
    • 0036829110 scopus 로고    scopus 로고
    • Increased exposure of anionic phospholipids on the surface of tumor blood vessels
    • S. Ran, A. Downes, and P.E. Thorpe Increased exposure of anionic phospholipids on the surface of tumor blood vessels Cancer Res. 62 2002 6132 6140 (Pubitemid 35244462)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6132-6140
    • Ran, S.1    Downes, A.2    Thorpe, P.E.3
  • 14
    • 0033968762 scopus 로고    scopus 로고
    • Flow cytometric estimation of the plasma membrane diversity of transplantable melanomas, using annexin V
    • M. Cichorek, K. Kozlowska, J.M. Witkowski, and M. Zarzeczna Flow cytometric estimation of the plasma membrane diversity of transplantable melanomas, using annexin V Folia Histochem. Cytobiol. 38 2000 41 43 (Pubitemid 30063971)
    • (2000) Folia Histochemica et Cytobiologica , vol.38 , Issue.1 , pp. 41-43
    • Cichorek, M.1    Kozlowska, K.2    Witkowski, J.M.3    Zarzeczna, M.4
  • 15
    • 33744916273 scopus 로고    scopus 로고
    • Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide
    • DOI 10.1158/0008-5472.CAN-05-4569
    • N. Papo, D. Seger, A. Makovitzki, V. Kalchenko, Z. Eshhar, H. Degani, and Y. Shai Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide Cancer Res. 66 2006 5371 5378 (Pubitemid 43844963)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5371-5378
    • Papo, N.1    Seger, D.2    Makovitzki, A.3    Kalchenko, V.4    Eshhar, Z.5    Degani, H.6    Shai, Y.7
  • 16
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I- restricted CTLS
    • DOI 10.1038/32183
    • M.L. Albert, B. Sauter, and N. Bhardwaj Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs Nature 392 1998 86 89 (Pubitemid 28150594)
    • (1998) Nature , vol.392 , Issue.6671 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 18
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • T. Miyashita, and J.C. Reed Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line Blood 81 1993 151 157 (Pubitemid 23013689)
    • (1993) Blood , vol.81 , Issue.1 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 19
    • 4143110396 scopus 로고    scopus 로고
    • Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: Membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion
    • DOI 10.1158/0008-5472.CAN-04-1438
    • N. Papo, A. Braunstein, Z. Eshhar, and Y. Shai Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide: membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion Cancer Res. 64 2004 5779 5786 (Pubitemid 39095578)
    • (2004) Cancer Research , vol.64 , Issue.16 , pp. 5779-5786
    • Papo, N.1    Braunstein, A.2    Eshhar, Z.3    Shai, Y.4
  • 20
    • 0036793131 scopus 로고    scopus 로고
    • Enhanced antitumor activity and selectivity of lactoferrin-derived peptides
    • DOI 10.1034/j.1399-3011.2002.21008.x
    • N. Yang, W. Stensen, J.S. Svendsen, and O. Rekdal Enhanced antitumor activity and selectivity of lactoferrin-derived peptides J. Pept. Res. 60 2002 187 197 (Pubitemid 35155428)
    • (2002) Journal of Peptide Research , vol.60 , Issue.4 , pp. 187-197
    • Yang, N.1    Rekdal, O.2    Stensen, W.3    Svendsen, J.S.4
  • 21
    • 28344438950 scopus 로고    scopus 로고
    • Lactoferricin: A lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties
    • DOI 10.1007/s00018-005-5373-z
    • J.L. Gifford, H.N. Hunter, and H.J. Vogel Lactoferricin: a lactoferrin-derived peptide with antimicrobial, antiviral, antitumor and immunological properties Cell Mol. Life Sci. 62 2005 2588 2598 (Pubitemid 41721232)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.22 , pp. 2588-2598
    • Gifford, J.L.1    Hunter, H.N.2    Vogel, H.J.3
  • 22
    • 0031034840 scopus 로고    scopus 로고
    • Differential scanning microcalorimetry indicates that human defensin, HNP-2, interacts specifically with biomembrane mimetic systems
    • DOI 10.1021/bi961300p
    • K. Lohner, A. Latal, R.I. Lehrer, and T. Ganz Differential scanning microcalorimetry indicates that human defensin, HNP-2, interacts specifically with biomembrane mimetic systems Biochemistry 36 1997 1525 1531 (Pubitemid 27074977)
    • (1997) Biochemistry , vol.36 , Issue.6 , pp. 1525-1531
    • Lohner, K.1    Latal, A.2    Lehrer, R.I.3    Ganz, T.4
  • 23
    • 18544366816 scopus 로고    scopus 로고
    • Host defense peptides as new weapons in cancer treatment
    • DOI 10.1007/s00018-005-4560-2
    • N. Papo, and Y. Shai Host defense peptides as new weapons in cancer treatment Cell Mol. Life Sci. 62 2005 784 790 (Pubitemid 40655628)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.7-8 , pp. 784-790
    • Papo, N.1    Shai, Y.2
  • 24
    • 38349009178 scopus 로고    scopus 로고
    • Studies on anticancer activities of antimicrobial peptides
    • D.W. Hoskin, and A. Ramamoorthy Studies on anticancer activities of antimicrobial peptides Biochim. Biophys. Acta 1778 2008 357 375
    • (2008) Biochim. Biophys. Acta , vol.1778 , pp. 357-375
    • Hoskin, D.W.1    Ramamoorthy, A.2
  • 25
    • 0036185339 scopus 로고    scopus 로고
    • Towards a structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides
    • DOI 10.1139/o01-213
    • H.J. Vogel, D.J. Schibli, W. Jing, E.M. Lohmeier-Vogel, R.F. Epand, and R.M. Epand Towards a structure-function analysis of bovine lactoferricin and related tryptophan- and arginine-containing peptides Biochem. Cell Biol. 80 2002 49 63 (Pubitemid 34194228)
    • (2002) Biochemistry and Cell Biology , vol.80 , Issue.1 , pp. 49-63
    • Vogel, H.J.1    Schibli, D.J.2    Jing, W.3    Lohmeier-Vogel, E.M.4    Epand, R.F.5    Epand, R.M.6
  • 26
    • 0035989171 scopus 로고    scopus 로고
    • Expression and functional activity of the ABC-transporter proteins P-glycoprotein and multidrug-resistance protein 1 in human brain tumor cells and astrocytes
    • DOI 10.1023/A:1015735815111
    • S. Spiegl-Kreinecker, J. Buchroithner, L. Elbling, E. Steiner, G. Wurm, A. Bodenteich, J. Fischer, M. Micksche, and W. Berger Expression and functional activity of the ABC-transporter proteins P-glycoprotein and multidrug-resistance protein 1 in human brain tumor cells and astrocytes J. Neurooncol. 57 2002 27 36 (Pubitemid 34692611)
    • (2002) Journal of Neuro-Oncology , vol.57 , Issue.1 , pp. 27-36
    • Spiegl-Kreinecker, S.1    Buchroithner, J.2    Elbling, L.3    Steiner, E.4    Wurm, G.5    Bodenteich, A.6    Fischer, J.7    Micksche, M.8    Berger, W.9
  • 29
    • 0035336409 scopus 로고    scopus 로고
    • Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells
    • M. Nesbit, H. Schaider, T.H. Miller, and M. Herlyn Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells J. Immunol. 166 2001 6483 6490 (Pubitemid 32467185)
    • (2001) Journal of Immunology , vol.166 , Issue.11 , pp. 6483-6490
    • Nesbit, M.1    Schaider, H.2    Miller, T.H.3    Herlyn, M.4
  • 32
    • 0014402405 scopus 로고
    • Phospholipids in tissues of the eye. I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids
    • R.M. Broekhuyse Phospholipids in tissues of the eye. I. Isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids Biochim. Biophys Acta 152 1968 307 315
    • (1968) Biochim. Biophys Acta , vol.152 , pp. 307-315
    • Broekhuyse, R.M.1
  • 33
    • 0025301753 scopus 로고    scopus 로고
    • Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase
    • P. Comfurius, J.M. Senden, R.H. Tilly, A.J. Schroit, E.M. Bevers, and R.F. Zwaal Loss of membrane phospholipid asymmetry in platelets and red cells may be associated with calcium-induced shedding of plasma membrane and inhibition of aminophospholipid translocase Biochim. Biophys. Acta 1026 2005 153 160
    • (2005) Biochim. Biophys. Acta , vol.1026 , pp. 153-160
    • Comfurius, P.1    Senden, J.M.2    Tilly, R.H.3    Schroit, A.J.4    Bevers, E.M.5    Zwaal, R.F.6
  • 34
    • 0025101650 scopus 로고
    • Role of calcium and calpain in complement-induced vesiculation of the platelet plasma membrane and in the exposure of the platelet factor Va receptor
    • DOI 10.1021/bi00455a005
    • T. Wiedmer, S.J. Shattil, M. Cunningham, and P.J. Sims Role of calcium and calpain in complement-induced vesiculation of the platelet plasma membrane and in the exposure of the platelet factor Va receptor Biochemistry 29 1990 623 632 (Pubitemid 20041941)
    • (1990) Biochemistry , vol.29 , Issue.3 , pp. 623-632
    • Wiedmer, T.1    Shattil, S.J.2    Cunningham, M.3    Sims, P.J.4
  • 35
    • 59449104221 scopus 로고    scopus 로고
    • Nanotubes, exosomes, and nucleic acid-binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: Implications in health and disease
    • M. Belting, and A. Wittrup Nanotubes, exosomes, and nucleic acid-binding peptides provide novel mechanisms of intercellular communication in eukaryotic cells: implications in health and disease J. Cell Biol. 183 2008 1187 1191
    • (2008) J. Cell Biol. , vol.183 , pp. 1187-1191
    • Belting, M.1    Wittrup, A.2
  • 36
    • 81155162004 scopus 로고    scopus 로고
    • Phosphatidylserine selective peptides as novel anti-cancer agents
    • Y. Manavbasi, D. Zweytick, R. Willumeit, and K. Lohner Phosphatidylserine selective peptides as novel anti-cancer agents Biophys. J. 96 2009 157
    • (2009) Biophys. J. , vol.96 , pp. 157
    • Manavbasi, Y.1    Zweytick, D.2    Willumeit, R.3    Lohner, K.4
  • 37
    • 80255137748 scopus 로고    scopus 로고
    • Targeting the cancer cell membrane specifically with human lactoferricin derivatives
    • S. Riedl, B. Rinner, S. Tumer, H. Schaider, K. Lohner, and D. Zweytick Targeting the cancer cell membrane specifically with human lactoferricin derivatives Ann. Oncol. 22 Suppl. 3 2011 33
    • (2011) Ann. Oncol. , vol.22 , Issue.SUPPL. 3 , pp. 33
    • Riedl, S.1    Rinner, B.2    Tumer, S.3    Schaider, H.4    Lohner, K.5    Zweytick, D.6
  • 38
    • 33744916273 scopus 로고    scopus 로고
    • Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide
    • DOI 10.1158/0008-5472.CAN-05-4569
    • N. Papo, D. Seger, A. Makovitzki, V. Kalchenko, Z. Eshhar, H. Degani, and Y. Shai Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide Cancer Res. 66 2006 5371 5378 (Pubitemid 43844963)
    • (2006) Cancer Research , vol.66 , Issue.10 , pp. 5371-5378
    • Papo, N.1    Seger, D.2    Makovitzki, A.3    Kalchenko, V.4    Eshhar, Z.5    Degani, H.6    Shai, Y.7
  • 39
    • 16844362681 scopus 로고    scopus 로고
    • Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibiotics
    • DOI 10.2174/1386207053764576
    • K. Lohner, and S.E. Blondelle Molecular mechanisms of membrane perturbation by antimicrobial peptides and the use of biophysical studies in the design of novel peptide antibiotics Comb. Chem. High Throughput Screen. 8 2005 241 256 (Pubitemid 40488604)
    • (2005) Combinatorial Chemistry and High Throughput Screening , vol.8 , Issue.3 , pp. 241-256
    • Lohner, K.1    Blondelle, S.E.2
  • 40
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • DOI 10.1038/415389a
    • M. Zasloff Antimicrobial peptides of multicellular organisms Nature 415 2002 389 395 (Pubitemid 34100944)
    • (2002) Nature , vol.415 , Issue.6870 , pp. 389-395
    • Zasloff, M.1
  • 41
    • 0034824597 scopus 로고    scopus 로고
    • From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides
    • DOI 10.1016/S0196-9781(01)00498-3, PII S0196978101004983
    • Y. Shai, and Z. Oren From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides Peptides 22 2001 1629 1641 (Pubitemid 32918242)
    • (2001) Peptides , vol.22 , Issue.10 , pp. 1629-1641
    • Shai, Y.1    Oren, Z.2
  • 42
    • 78649813603 scopus 로고    scopus 로고
    • Optimization and high-throughput screening of antimicrobial peptides
    • S.E. Blondelle, and K. Lohner Optimization and high-throughput screening of antimicrobial peptides Curr. Pharm. Des. 16 2010 3204 3211
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 3204-3211
    • Blondelle, S.E.1    Lohner, K.2
  • 43
    • 0037961563 scopus 로고    scopus 로고
    • MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain
    • K.J. Hallock, D.K. Lee, and A. Ramamoorthy MSI-78, an analogue of the magainin antimicrobial peptides, disrupts lipid bilayer structure via positive curvature strain Biophys. J. 84 2005 3052 3060 (Pubitemid 36531755)
    • (2003) Biophysical Journal , vol.84 , Issue.5 , pp. 3052-3060
    • Hallock, K.J.1    Lee, D.-K.2    Ramamoorthy, A.3
  • 44
    • 0042573730 scopus 로고    scopus 로고
    • New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells
    • DOI 10.1021/bi027212o
    • N. Papo, and Y. Shai New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells Biochemistry 42 2003 9346 9354 (Pubitemid 36959242)
    • (2003) Biochemistry , vol.42 , Issue.31 , pp. 9346-9354
    • Papo, N.1    Shai, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.