Hallmarks of senescence in carcinogenesis and cancer therapy

Oncogene

Volumn 23, Issue 16 REV. ISS. 2, 2004, Pages 2919-2933

  Shay, Jerry W ^a   Roninson, Igor B ^b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b ORDWAY RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; Chemotherapy; Mitotic catastrophe; Replicative senescence; STASIS; Telomeres

Indexed keywords

ANTIESTROGEN; ANTINEOPLASTIC AGENT; APHIDICOLIN; BUTYRIC ACID; CISPLATIN; CONNECTIVE TISSUE GROWTH FACTOR; CYTARABINE; DOXORUBICIN; ETOPOSIDE; MASPIN; MITOGEN ACTIVATED PROTEIN KINASE; PACLITAXEL; PROTEIN BCL 2; PROTEIN DERIVATIVE; PROTEIN P16; PROTEIN P53; RETINOID; TRANSCRIPTION FACTOR E2F1; VINCRISTINE; H2AFX PROTEIN, HUMAN; HISTONE; TELOMERASE;

CANCER RADIOTHERAPY; CANCER THERAPY; CARCINOGENESIS; CELL AGING; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL DIVISION; CELL FUNCTION; CELL PROLIFERATION; CELL STIMULATION; DNA DAMAGE; DNA REPAIR; FIBROBLAST; FRAGMENTATION REACTION; GENE DELETION; GENE MUTATION; GENE OVEREXPRESSION; GENE REPLICATION; GENE TRANSLOCATION; HUMAN; KNOCKOUT GENE; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SENESCENCE; SIGNAL TRANSDUCTION; TELOMERE; TUMOR CELL; ANIMAL; GENE EXPRESSION REGULATION; MOUSE; NEOPLASM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL AGING; DNA REPAIR; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HUMANS; MICE; NEOPLASMS; RETINOIDS; SIGNAL TRANSDUCTION; TELOMERASE; TELOMERE;

EID: 2342570379     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207518     Document Type: Review

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