Necrosis avidity of 99mTc(CO)3-labeled pamoic acid derivatives: Synthesis and preliminary biological evaluation in animal models of necrosis

Bioconjugate Chemistry

Volumn 18, Issue 6, 2007, Pages 1924-1934

  Fonge, Humphrey ^a   Chitneni, Satish K ^a   Lixin, Jin ^a   Vunckx, Kathleen ^b   Prinsen, Kristof ^a   Nuyts, Johan ^b   Mortelmans, Luc ^a   Bormans, Guy ^a   Ni, Yicheng ^b   Verbruggen, Alfons ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

RADIOGRAPHY; RATS; SYNTHESIS (CHEMICAL);

ACID DERIVATIVE; ANIMAL MODEL; BIOLOGICAL EVALUATION; DERIVATIVE SYNTHESIS; IN-VITRO; IN-VIVO; NECROTIC TISSUE; POST INJECTION; PROPERTY; RADIOLABELLING;

TISSUE;

ALCOHOL; EMBONIC ACID; EOSIN; HEMATOXYLIN; HISTIDINE; N,N' BIS(DIETHYLENETRIAMINOPENTAACETATO) 4,4' METHYLENE BIS(2 HYDROXY 3 NAPHTHOIC HYDRAZIDE); TRACER; TRICARBONYL TC 99M; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG; [N (5 AMINOPENTYL)PYRIDIN 2 YL METHYLAMINO]METHYLACETO 4,4' METHYLENE 2 HYDROXY 3 NAPTHALENECARBOXAMIDE (2' HYDROXY 3' NAPHTHOIC ACID METHYLESTER);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG BINDING; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SPECIFICITY; DRUG STABILITY; DRUG STORAGE; DRUG SYNTHESIS; DRUG TISSUE LEVEL; DRUG UPTAKE; EX VIVO STUDY; HISTOCHEMISTRY; IN VIVO STUDY; INFARCTION; ISOTOPE LABELING; KIDNEY CLEARANCE; LIPOPHILICITY; LIVER; LIVER CLEARANCE; LIVER NECROSIS; MUSCLE NECROSIS; NECROSIS; NONHUMAN; PLASMA; PLASMA CLEARANCE; QUANTITATIVE ANALYSIS; RADIOCHEMISTRY; RAT; ROOM TEMPERATURE; TISSUE SECTION; URINE;

ANIMALIA; MUS; RATTUS;

EID: 36849080452     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc700236j     Document Type: Article

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