Activatable molecular systems using homologous near-infrared fluorescent Probes for monitoring enzyme activities in vitro, in pCellulo, and in vivo

Molecular Pharmaceutics

Volumn 6, Issue 2, 2009, Pages 416-427

  Zhang, Zongren ^a   Fan, Jinda ^a   Cheney, Philip P ^a   Berezin, Mikhail Y ^a   Edwards, W Barry ^a   Akers, Walter J ^a   Shen, Duanwen ^a   Liang, Kexian ^a   Culver, Joseph P ^a   Achilefu, Samuel ^a,b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activatable probes; Caspase; Enzyme; FRET; Kinetics; Near infrared fluorescence; Quenching mechanism

Indexed keywords

CASPASE 3; CYANINE DYE; FLUORESCENT DYE; PACLITAXEL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; MOLECULAR MODEL; MOLECULAR PROBE; MOUSE; NEAR INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CASPASE 3; ENZYME ACTIVATION; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; HUMANS; KINETICS; LUNG NEOPLASMS; MALE; MICE; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; PACLITAXEL; TUMOR CELLS, CULTURED;

EID: 64649101405     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp800264k     Document Type: Article

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