-
1
-
-
0036463649
-
Apoptosis-based therapies
-
Reed JC (2002) Apoptosis-based therapies. Nat Rev Drug Discov 1:111-121.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 111-121
-
-
Reed, J.C.1
-
2
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0034544590
-
Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma
-
Chang J, et al. (2000) Apoptosis and proliferation as predictors of chemotherapy response in patients with breast carcinoma. Cancer 89:2145-2152.
-
(2000)
Cancer
, vol.89
, pp. 2145-2152
-
-
Chang, J.1
-
4
-
-
0031886737
-
In vitro radiation-induced apoptosis and early response to low-dose radiotherapy in non-Hodgkin's lymphomas
-
DOI 10.1016/S0167-8140(97)00148-5, PII S0167814097001485
-
Dubray B, et al. (1998) In vitro radiation-induced apoptosis and early response to low-dose radiotherapy in non-Hodgkin's lymphomas. Radiother Oncol 46:185-191. (Pubitemid 28109177)
-
(1998)
Radiotherapy and Oncology
, vol.46
, Issue.2
, pp. 185-191
-
-
Dubray, B.1
Breton, C.2
Delic, J.3
Klijanienko, J.4
Maciorowski, Z.5
Vielh, P.6
Fourquet, A.7
Dumont, J.8
Magdelenat, H.9
Cosset, J.-M.10
-
5
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
Eisenhauer EA, et al. (2009) New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer 45:228-247.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
-
7
-
-
0344142396
-
Emerging roles of caspase-3 in apoptosis
-
Porter AG, Janicke RU (1999) Emerging roles of caspase-3 in apoptosis. Cell Death Differ 6:99-104.
-
(1999)
Cell Death Differ
, vol.6
, pp. 99-104
-
-
Porter, A.G.1
Janicke, R.U.2
-
8
-
-
28144443339
-
N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: Synthesis, in vitro activity, and molecular modeling studies
-
DOI 10.1021/jm0506625
-
Chu W, et al. (2005) N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies J Med Chem 48:7637-7647. (Pubitemid 41698804)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.24
, pp. 7637-7647
-
-
Chu, W.1
Zhang, J.2
Zeng, C.3
Rothfuss, J.4
Tu, Z.5
Chu, Y.6
Reichert, D.E.7
Welch, M.J.8
Mach, R.H.9
-
9
-
-
0034717269
-
Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality
-
DOI 10.1074/jbc.275.21.16007
-
Lee D, et al. (2000) Potent and selective nonpeptide inhibitors of caspases 3 and 7 inhibit apoptosis and maintain cell functionality. J Biol Chem 275:16007-16014. (Pubitemid 30366906)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.21
, pp. 16007-16014
-
-
Lee, D.1
Long, S.A.2
Adams, J.L.3
Chan, G.4
Vaidya, K.S.5
Francis, T.A.6
Kikly, K.7
Winkler, J.D.8
Sung, C.-M.9
Debouck, C.10
Richardson, S.11
Levy, M.A.12
Dewolf Jr., W.E.13
Keller, P.M.14
Tomaszek, T.15
Head, M.S.16
Ryan, M.D.17
Haltiwanger, R.C.18
Liang, P.-H.19
Janson, C.A.20
McDevitt, P.J.21
Johanson, K.22
Concha, N.O.23
Chan, W.24
Abdel-Meguid, S.S.25
Badger, A.M.26
Lark, M.W.27
Nadeau, D.P.28
Suva, L.J.29
Gowen, M.30
Nuttall, M.E.31
more..
-
10
-
-
34249719936
-
18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent
-
Faust A, et al. (2007) The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)s ulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent. Q J Nucl Med Mol Imaging 51:67-73. (Pubitemid 46824663)
-
(2007)
Quarterly Journal of Nuclear Medicine and Molecular Imaging
, vol.51
, Issue.1
, pp. 67-73
-
-
Faust, A.1
Wagner, S.2
Law, M.P.3
Hermann, S.4
Schnockel, U.5
Keul, P.6
Schober, O.7
Schafers, M.8
Levkau, B.9
Kopka, K.10
-
11
-
-
33750976699
-
5-Pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis
-
DOI 10.1021/jm051217c
-
Kopka K, et al. (2006) 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis. J Med Chem 49:6704-6715. (Pubitemid 44749738)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.23
, pp. 6704-6715
-
-
Kopka, K.1
Faust, A.2
Keul, P.3
Wagner, S.4
Breyholz, H.-J.5
Holtke, C.6
Schober, O.7
Schafers, M.8
Levkau, B.9
-
12
-
-
66749110952
-
[18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: Synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98
-
Zhou D, et al. (2009) [18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: Synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98. Org Biomol Chem 7:1337-1348.
-
(2009)
Org Biomol Chem
, vol.7
, pp. 1337-1348
-
-
Zhou, D.1
-
13
-
-
66749129069
-
Fluorinated isatin derivatives. Part 2: New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis
-
Podichetty AK, et al. (2009) Fluorinated isatin derivatives. Part 2: New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis. J Med Chem 52:3484-3495.
-
(2009)
J Med Chem
, vol.52
, pp. 3484-3495
-
-
Podichetty, A.K.1
-
14
-
-
62949137154
-
Fluorinated isatin derivatives. Part 1: Synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatins as potent caspase-3 and -7 inhibitors
-
Podichetty AK, et al. (2009) Fluorinated isatin derivatives. Part 1: Synthesis of new N-substituted (S)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl] isatins as potent caspase-3 and -7 inhibitors. Bioorg Med Chem 17:2680-2688.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 2680-2688
-
-
Podichetty, A.K.1
-
15
-
-
33747355468
-
18F-labeled isatin analog for imaging caspase-3 activation in apoptosis
-
DOI 10.1016/j.bmcl.2006.07.045, PII S0960894X06008195
-
Zhou D, et al. (2006) Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis. Bioorg Med Chem Lett 16:5041-5046. (Pubitemid 44247712)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.19
, pp. 5041-5046
-
-
Zhou, D.1
Chu, W.2
Rothfuss, J.3
Zeng, C.4
Xu, J.5
Jones, L.6
Welch, M.J.7
Mach, R.H.8
-
16
-
-
0037339961
-
Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: Early assessment predicts clinical response
-
Davis DW, et al. (2003) Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response. Clin Cancer Res 9:955-960.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 955-960
-
-
Davis, D.W.1
-
17
-
-
20244378529
-
Neoadjuvant trastuzumab induces apoptosis in primary breast cancers
-
Mohsin SK, et al. (2005) Neoadjuvant trastuzumab induces apoptosis in primary breast cancers. J Clin Oncol 23:2460-2468.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2460-2468
-
-
Mohsin, S.K.1
-
18
-
-
58149090677
-
Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide
-
Smith G, et al. (2008) Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide. J Med Chem 51:8057-8067.
-
(2008)
J Med Chem
, vol.51
, pp. 8057-8067
-
-
Smith, G.1
-
19
-
-
69049090660
-
MCF-7 breast carcinoma cells do not express caspase-3
-
Janicke RU (2008) MCF-7 breast carcinoma cells do not express caspase-3. Breast Cancer Res Treat.
-
(2008)
Breast Cancer Res Treat
-
-
Janicke, R.U.1
-
20
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
Cohen GM (1997) Caspases: The executioners of apoptosis. Biochem J 326:1-16.
-
(1997)
Biochem J
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
21
-
-
45449097463
-
No death without life: Vital functions of apoptotic effectors
-
DOI 10.1038/cdd.2008.28, PII CDD200828, Special Issue to celebrate Richard Lockshin's 70th Birthday
-
Galluzzi L, et al. (2008) No death without life: Vital functions of apoptotic effectors. Cell Death Differ 15:1113-1123. (Pubitemid 351850963)
-
(2008)
Cell Death and Differentiation
, vol.15
, Issue.7
, pp. 1113-1123
-
-
Galluzzi, L.1
Joza, N.2
Tasdemir, E.3
Maiuri, M.C.4
Hengartner, M.5
Abrams, J.M.6
Tavernarakis, N.7
Penninger, J.8
Madeo, F.9
Kroemer, G.10
-
22
-
-
22544432640
-
Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death
-
DOI 10.1038/sj.cdd.4401724, PII 4401724
-
Kroemer G, et al. (2009) Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ 16:3-11. (Pubitemid 41553979)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.SUPPL. 2
, pp. 1463-1467
-
-
Kroemer, G.1
El-Deiry, W.S.2
Golstein, P.3
Peter, M.E.4
Vaux, D.5
Vandenabeele, P.6
Zhivotovsky, B.7
Blagosklonny, M.V.8
Malorni, W.9
Knight, R.A.10
Piacentini, M.11
Nagata, S.12
Melino, G.13
-
23
-
-
39749123276
-
Apoptosis and necrosis: Detection, discrimination and phagocytosis
-
DOI 10.1016/j.ymeth.2007.12.001, PII S1046202308000029
-
Krysko DV, Vanden Berghe T, D'Herde K, Vandenabeele P (2008) Apoptosis and necrosis: Detection, discrimination and phagocytosis. Methods 44:205-221. (Pubitemid 351296447)
-
(2008)
Methods
, vol.44
, Issue.3
, pp. 205-221
-
-
Krysko, D.V.1
Vanden Berghe, T.2
D'Herde, K.3
Vandenabeele, P.4
-
24
-
-
0035821595
-
Potent and selective nonpeptide inhibitors of caspases 3 and 7
-
DOI 10.1021/jm0100537
-
Lee D, et al. (2001) Potent and selective nonpeptide inhibitors of caspases 3 and 7. J Med Chem 44:2015-2026. (Pubitemid 32884524)
-
(2001)
Journal of Medicinal Chemistry
, vol.44
, Issue.12
, pp. 2015-2026
-
-
Lee, D.1
Long, S.A.2
Murray, J.H.3
Adams, J.L.4
Nuttall, M.E.5
Nadeau, D.P.6
Kikly, K.7
Winkler, J.D.8
Sung, C.-M.9
Ryan, M.D.10
Levy, M.A.11
Keller, P.M.12
Dewolf Jr., W.E.13
-
25
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
Browder T, et al. (2000) Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 60:1878-1886. (Pubitemid 30207647)
-
(2000)
Cancer Research
, vol.60
, Issue.7
, pp. 1878-1886
-
-
Browder, T.1
Butterfield, C.E.2
Kraling, B.M.3
Shi, B.4
Marshall, B.5
O'Reilly, M.S.6
Folkman, J.7
-
26
-
-
0034022634
-
Tissue transglutaminase in the small intestine of the mouse as a marker for apoptotic cells. Colocalization with DNA fragmentation
-
Aschoff AP, Gunther E, Jirikowski GF (2000) Tissue transglutaminase in the small intestine of the mouse as a marker for apoptotic cells. Colocalization with DNA fragmentation. Histochem Cell Biol 113:313-317. (Pubitemid 30256974)
-
(2000)
Histochemistry and Cell Biology
, vol.113
, Issue.4
, pp. 313-317
-
-
Aschoff, A.P.1
Gunther, E.2
Jirikowski, G.F.3
-
27
-
-
21244495995
-
1H MRS-visible lipids accumulate during apoptosis of lymphoma cells in vitro and in vivo
-
DOI 10.1002/mrm.20529
-
Schmitz JE, Kettunen MI, Hu DE, Brindle KM (2005) 1H MRS-visible lipids accumulate during apoptosis of lymphoma cells in vitro and in vivo. Magn Reson Med 54:43-50. (Pubitemid 40898395)
-
(2005)
Magnetic Resonance in Medicine
, vol.54
, Issue.1
, pp. 43-50
-
-
Schmitz, J.E.1
Kettunen, M.I.2
Hu, D.-E.3
Brindle, K.M.4
-
28
-
-
0030047282
-
1H-NMR spectroscopy in a murine tumour in vivo
-
Zhao M, Pipe JG, Bonnett J, Evelhoch JL (1996) Early detection of treatment response by diffusion-weighted 1H-NMR spectroscopy in a murine tumour in vivo. Br J Cancer 73:61-64. (Pubitemid 126422064)
-
(1996)
British Journal of Cancer
, vol.73
, Issue.1
, pp. 61-64
-
-
Zhao, M.1
Pipe, J.G.2
Bonnett, J.3
Evelhoch, J.L.4
-
29
-
-
40949121437
-
Detection of cell death in tumors by using MR imaging and a gadolinium-based targeted contrast agent
-
Krishnan AS, et al. (2008) Detection of cell death in tumors by using MR imaging and a gadolinium-based targeted contrast agent. Radiology 246:854-862.
-
(2008)
Radiology
, vol.246
, pp. 854-862
-
-
Krishnan, A.S.1
-
30
-
-
54249113290
-
Ultrasound imaging of apoptosis in tumor response: Novel preclinical monitoring of photodynamic therapy effects
-
Banihashemi B, et al. (2008) Ultrasound imaging of apoptosis in tumor response: novel preclinical monitoring of photodynamic therapy effects. Cancer Res 68:8590-8596.
-
(2008)
Cancer Res
, vol.68
, pp. 8590-8596
-
-
Banihashemi, B.1
-
31
-
-
34250667135
-
Radiolabeling of HYNIC-annexin V with technetium-99m for in vivo imaging of apoptosis
-
Blankenberg FG, Vanderheyden JL, Strauss HW, Tait JF (2006) Radiolabeling of HYNIC-annexin V with technetium-99m for in vivo imaging of apoptosis. Nat Protoc 1:108-110.
-
(2006)
Nat Protoc
, vol.1
, pp. 108-110
-
-
Blankenberg, F.G.1
Vanderheyden, J.L.2
Strauss, H.W.3
Tait, J.F.4
-
32
-
-
0242329769
-
In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope
-
Collingridge DR, et al. (2003) In vitro selectivity, in vivo biodistribution and tumour uptake of annexin V radiolabelled with a positron emitting radioisotope Br J Cancer 89:1327-1333.
-
(2003)
Br J Cancer
, vol.89
, pp. 1327-1333
-
-
Collingridge, D.R.1
-
33
-
-
60649115423
-
Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis
-
Grimberg H, et al. (2009) Monitoring of tumor response to chemotherapy in vivo by a novel small-molecule detector of apoptosis. Apoptosis 14:257-267.
-
(2009)
Apoptosis
, vol.14
, pp. 257-267
-
-
Grimberg, H.1
-
34
-
-
0037742189
-
18f]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography
-
Barthel H, et al. (2003) 3-′-deoxy-3′-[18F]fluorothymidine as a new marker for monitoring tumor response to antiproliferative therapy in vivo with positron emission tomography. Cancer Res 63:3791-3798. (Pubitemid 36793068)
-
(2003)
Cancer Research
, vol.63
, Issue.13
, pp. 3791-3798
-
-
Barthel, H.1
Cleij, M.C.2
Collingridge, D.R.3
Hutchinson, O.C.4
Osman, S.5
He, Q.6
Luthra, S.K.7
Brady, F.8
Price, P.M.9
Aboagye, E.O.10
-
35
-
-
34548173711
-
18F]fluorothymidine positron emission tomography
-
DOI 10.1007/s00259-007-0379-4
-
Kenny L, et al. (2007) Imaging early changes in proliferation at 1 week post chemotherapy: A pilot study in breast cancer patients with 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography. Eur J Nucl Med Mol Imaging 34:1339-1347. (Pubitemid 47312585)
-
(2007)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.34
, Issue.9
, pp. 1339-1347
-
-
Kenny, L.1
Coombes, R.C.2
Vigushin, D.M.3
Al-Nahhas, A.4
Shousha, S.5
Aboagye, E.O.6
-
36
-
-
20144366731
-
18F]fluorothymidine positron emission tomography: The effect of cisplatin on a fibrosarcoma tumor model in vivo
-
DOI 10.1158/0008-5472.CAN-04-4008
-
Leyton J, et al. (2005) Early detection of tumor response to chemotherapy by 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography: The effect of cisplatin on a fibrosarcoma tumor model in vivo. Cancer Res 65:4202-4210. (Pubitemid 40775658)
-
(2005)
Cancer Research
, vol.65
, Issue.10
, pp. 4202-4210
-
-
Leyton, J.1
Latigo, J.R.2
Perumal, M.3
Dhaliwal, H.4
He, Q.5
Aboagye, E.O.6
-
37
-
-
1642368865
-
Thrombospondin-1 Associated with Tumor Microenvironment Contributes to Low-Dose Cyclophosphamide-Mediated Endothelial Cell Apoptosis and Tumor Growth Suppression
-
DOI 10.1158/0008-5472.CAN-03-3126
-
Hamano Y, et al. (2004) Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res 64:1570-1574. (Pubitemid 38428672)
-
(2004)
Cancer Research
, vol.64
, Issue.5
, pp. 1570-1574
-
-
Hamano, Y.1
Sugimoto, H.2
Soubasakos, M.A.3
Kieran, M.4
Olsen, B.R.5
Lawler, J.6
Sudhakar, A.7
Kalluri, R.8
|