Pretargeting of necrotic tumors with biotinylated hypericin using 123I-labeled avidin: Evaluation of a twostep strategy

Investigational New Drugs

Volumn 30, Issue 6, 2012, Pages 2132-2140

  Marysael, Thierry ^a   Bauwens, Matthias ^b   Ni, Yicheng ^b   Bormans, Guy ^b   Rozenski, Jef ^b   De Witte, Peter ^a  

^a Faculteit Farmaceutische Wetenschappen   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Avidin; Biotin; Hypericin; Pretargeting; Tumor necrosis therapy

Indexed keywords

AVIDIN; AVIDIN I 123; BIOTIN DERIVATIVE; DICYCLOHEXYLCARBODIIMIDE; ETHYLENEDIAMINE; HYPERICIN; HYPERICIN BIOTIN; N HYDROXYSUCCINIMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG TARGETING; FEASIBILITY STUDY; FEMALE; FLUORESCENCE MICROSCOPY; LIVER NECROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR NECROSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; AVIDIN; BIOTIN; BIOTINYLATION; CELL LINE, TUMOR; CONTRAST MEDIA; ETHANOL; FEMALE; IODINE RADIOISOTOPES; MICE; MICE, INBRED C3H; NECROSIS; NEOPLASMS; PERYLENE; TISSUE DISTRIBUTION;

EID: 84875521135     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-011-9778-2     Document Type: Article

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