SCOPUS 정보 검색 플랫폼

Comprehensive Natural Products II: Chemistry and Biology

Volumn 1, Issue , 2010, Pages 385-452

Type I modular PKS

(2) Hill, Alison M a Staunton, James b

a UNIVERSITY OF EXETER (United Kingdom)

b UNIVERSITY OF CAMBRIDGE (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79954961819 PISSN: None EISSN: None Source Type: Book
DOI: None Document Type: Chapter

Times cited : (5)

References (240)

1
- 0000809097
- J. N. Collie; W. S. Myers, J. Chem. Soc. 1893, 63, 122.
- (1893) J. Chem. Soc , vol.63 , pp. 122
- Collie, J.N.¹ Myers, W.S.²

2
- 34848847286
- J. N. Collie, J. Chem. Soc. 1907, 91, 1806.
- (1907) J. Chem. Soc , vol.91 , pp. 1806
- Collie, J.N.¹

3
- 84970596098
- A. J. Birch; P. A. Massy-Westropp; C. J. Moye, Aus. J. Chem. 1955, 8, 539.
- (1955) Aus. J. Chem , vol.8 , pp. 539
- Birch, A.J.¹ Massy-westropp, P.A.² Moye, C.J.³

4
- 0034887171
- J. Staunton; K. J. Weissman, Nat. Prod. Rep. 2001, 18, 380.
- (2001) Nat. Prod. Rep , vol.18 , pp. 380
- Staunton, J.¹ Weissman, K.J.²

5
- 84906296138
- A. M. Hill, Nat. Prod. Rep. 2006, 23, 139.
- (2006) Nat. Prod. Rep , vol.23 , pp. 139
- Hill, A.M.¹

6
- 84906286148
- Polyketide Biosynthesis, Modular Polyketide Synthases
- T. P. Begly, Ed.; John Wiley and Sons, doi: 10.1002/9780470048672.wecb459
- T. J. Buchholz; J. D. Kittendorf; D. H. Sherman, Polyketide Biosynthesis, Modular Polyketide Synthases. In Wiley Encyclopedia of Chemical Biology; T. P. Begly, Ed.; John Wiley and Sons, 2008, doi: 10.1002/9780470048672.wecb459.
- (2008) Wiley Encyclopedia of Chemical Biology
- Buchholz, T.J.¹ Kittendorf, J.D.² Sherman, D.H.³

7
- 0037398774
- B. Shen, Curr. Opin. Chem. Biol. 2003, 7, 285.
- (2003) Curr. Opin. Chem. Biol , vol.7 , pp. 285
- Shen, B.¹

8
- 44649201476
- S. G. Van Lanen; B. Shen, Curr. Top. Med. Chem. 2008, 8, 448.
- (2008) Curr. Top. Med. Chem , vol.8 , pp. 448
- Van Lanen, S.G.¹ Shen, B.²

9
- 36348982083
- S. C. Wenzel; R. Müller, Nat. Prod. Rep. 2007, 24, 1211.
- (2007) Nat. Prod. Rep , vol.24 , pp. 1211
- Wenzel, S.C.¹ Müller, R.²

10
- 33846923183
- C. Hertweck; A. Luzhetsky; Y. Rebets; A. Bechthold, Nat. Prod. Rep. 2007, 24, 162.
- (2007) Nat. Prod. Rep , vol.24 , pp. 162
- Hertweck, C.¹ Luzhetsky, A.² Rebets, Y.³ Bechthold, A.⁴

11
- 84906290432
- K. Watanabe; A. P. Praseuth; C. C. Wang, Curr. Opin. Chem. Biol. 2007, 279.
- (2007) Curr. Opin. Chem. Biol , pp. 279
- Watanabe, K.¹ Praseuth, A.P.² Wang, C.C.³

12
- 34547129927
- R. O. Brady, Proc. Natl. Acad. Sci. U.S.A. 1958, 44, 993.
- (1958) Proc. Natl. Acad. Sci. U.S.A , vol.44 , pp. 993
- Brady, R.O.¹

13
- 84906293425
- S. J. Wakil, J. Am. Chem. Soc. 1958, 880, 6465.
- (1958) J. Am. Chem. Soc , vol.880 , pp. 6465
- Wakil, S.J.¹

14
- 0037965730
- S. J. Wakil, J. Lipid Res. 1961, 2, 1.
- (1961) J. Lipid Res , vol.2 , pp. 1
- Wakil, S.J.¹

15
- 34848843433
- S. Smith; S.-C. Tsai, Nat. Prod. Rep. 2007, 24, 1041.
- (2007) Nat. Prod. Rep , vol.24 , pp. 1041
- Smith, S.¹ Tsai, S.-C.²

16
- 33746776204
- Y. Tang; C.-Y. Kim; I. I. Matthews; D. E. Cane; C. Khosla, Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 11124.
- (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 11124
- Tang, Y.¹ Kim, C.-Y.² Matthews, I.I.³ Cane, D.E.⁴ Khosla, C.⁵

17
- 0041317602
- M. A. Reed; M. Schweizer; A. E. Szafranska; C. Arthur; T. P. Nicholson; R. J. Cox; J. Crosby; M. P. Crump; T. J. Simpson, Org. Biol. Chem. 2003, 1, 463.
- (2003) Org. Biol. Chem , vol.1 , pp. 463
- Reed, M.A.¹ Schweizer, M.² Szafranska, A.E.³ Arthur, C.⁴ Nicholson, T.P.⁵ Cox, R.J.⁶ Crosby, J.⁷ Crump, M.P.⁸ Simpson, T.J.⁹

18
- 34447516335
- Y. Y. Tang; A. Y. Chen; C. Y. Kim; D. E. Cane; C. Khosla, Chem. Biol. 2007, 14, 931.
- (2007) Chem. Biol , vol.14 , pp. 931
- Tang, Y.Y.¹ Chen, A.Y.² Kim, C.Y.³ Cane, D.E.⁴ Khosla, C.⁵

19
- 0000032793
- S. I. Chang; C. G. Hammes, Acc. Chem. Res. 1990, 23, 363.
- (1990) Acc. Chem. Res , vol.23 , pp. 363
- Chang, S.I.¹ Hammes, C.G.²

20
- 0031424745
- A. Witkowski; A. Joshi; K. S. Smith, Biochemistry 1997, 36, 16338.
- (1997) Biochemistry , vol.36 , pp. 16338
- Witkowski, A.¹ Joshi, A.² Smith, K.S.³

21
- 0017805075
- C. Y. Lin; S. Smith, J. Biol. Chem. 1978, 253, 1954.
- (1978) J. Biol. Chem , vol.253 , pp. 1954
- Lin, C.Y.¹ Smith, S.²

22
- 34247353309
- M. Leibundgut; S. Jenni; C. Frick; N. Ban, Science 2007, 316, 288.
- (2007) Science , vol.316 , pp. 288
- Leibundgut, M.¹ Jenni, S.² Frick, C.³ Ban, N.⁴

23
- 0014056841
- J. R. Martin; W. Rosenbrook, Biochemistry 1967, 6, 435.
- (1967) Biochemistry , vol.6 , pp. 435
- Martin, J.R.¹ Rosenbrook, W.²

24
- 34547930907
- C. Khosla; Y. Tang; A. Y. Chen; N. A. Schnarr; D. E. Cane, Annu. Rev. Biochem. 2007, 76, 195.
- (2007) Annu. Rev. Biochem , vol.76 , pp. 195
- Khosla, C.¹ Tang, Y.² Chen, A.Y.³ Schnarr, N.A.⁴ Cane, D.E.⁵

25
- 0031271543
- J. Staunton; B. Wilkinson, Chem. Rev. 1997, 97, 2611.
- (1997) Chem. Rev , vol.97 , pp. 2611
- Staunton, J.¹ Wilkinson, B.²

26
- 0035043763
- B. J. Rawlings, Nat. Prod. Rep. 2001, 18, 190.
- (2001) Nat. Prod. Rep , vol.18 , pp. 190
- Rawlings, B.J.¹

27
- 0021052357
- D. E. Cane; H. Hasler; P. B. Taylor; T. C. Liang, Tetrahedron 1983, 39, 3449.
- (1983) Tetrahedron , vol.39 , pp. 3449
- Cane, D.E.¹ Hasler, H.² Taylor, P.B.³ Liang, T.C.⁴

28
- 0013533182
- S. M. Friedman; J. W. Corcoran; T. Kaneda, J. Biol. Chem. 1964, 239, 2386.
- (1964) J. Biol. Chem , vol.239 , pp. 2386
- Friedman, S.M.¹ Corcoran, J.W.² Kaneda, T.³

29
- 0343122173
- T. Kaneda; J. C. Butte; S. B. Taubman; J. W. Corcoran, J. Biol. Chem. 1962, 237, 322.
- (1962) J. Biol. Chem , vol.237 , pp. 322
- Kaneda, T.¹ Butte, J.C.² Taubman, S.B.³ Corcoran, J.W.⁴

30
- 0023098840
- D. E. Cane; C. C. Yang, J. Am. Chem. Soc. 1987, 109, 1255.
- (1987) J. Am. Chem. Soc , vol.109 , pp. 1255
- Cane, D.E.¹ Yang, C.C.²

31
- 17944390314
- P. Dimroth; H. Walter; F. Lynen, Eur. J. Biochem. 1970, 13, 98.
- (1970) Eur. J. Biochem , vol.13 , pp. 98
- Dimroth, P.¹ Walter, H.² Lynen, F.³

32
- 0027530225
- P. M. Schoolingin-Jordan; J. B. Spencer, Biochem. Soc. Trans. 1993, 21, 222.
- (1993) Biochem. Soc. Trans , vol.21 , pp. 222
- Schoolingin-jordan, P.M.¹ Spencer, J.B.²

33
- 0027054628
- J. B. Spencer; P. M. Schoolingin-Jordan, Biochem. J. 1992, 288, 839.
- (1992) Biochem. J , vol.288 , pp. 839
- Spencer, J.B.¹ Schoolingin-jordan, P.M.²

34
- 0029775915
- C. J. Child; J. B. Spencer; P. Bhogal; P. M. Schoolingin-Jordan, Biochemistry 1996, 35, 12267.
- (1996) Biochemistry , vol.35 , pp. 12267
- Child, C.J.¹ Spencer, J.B.² Bhogal, P.³ Schoolingin-jordan, P.M.⁴

35
- 0021238139
- F. H. Malpartida; D. A. Hopwood, Nature 1984, 309, 462.
- (1984) Nature , vol.309 , pp. 462
- Malpartida, F.H.¹ Hopwood, D.A.²

36
- 0004269298
- D. A. Hopwood; D. H. Sherman, Annu. Rev. Genet. 1990, 24, 67.
- (1990) Annu. Rev. Genet , vol.24 , pp. 67
- Hopwood, D.A.¹ Sherman, D.H.²

37
- 0001747786
- D. A. Hopwood, Chem. Rev. 1997, 97, 2465.
- (1997) Chem. Rev , vol.97 , pp. 2465
- Hopwood, D.A.¹

38
- 0023121014
- F. Malpartida; S. E. Halla; H. M. Kieser; H. Motamedi; C. R. Hutchinson; M. J. Butler; D. A. Sugden; M. Warren; C. McKillop; C. R. Bailey; G. O. Humphreys; D. A. Hopwood, Nature 1987, 325, 818.
- (1987) Nature , vol.325 , pp. 818
- Malpartida, F.¹ Halla, S.E.² Kieser, H.M.³ Motamedi, H.⁴ Hutchinson, C.R.⁵ Butler, M.J.⁶ Sugden, D.A.⁷ Warren, M.⁸ McKillop, C.⁹ Bailey, C.R.¹⁰ Humphreys, G.O.¹¹ Hopwood, D.A.¹²

39
- 0020367857
- C. J. Thompson; J. M. Ward; D. A. Hopwood, J. Bacteriol. 1982, 151, 668.
- (1982) J. Bacteriol , vol.151 , pp. 668
- Thompson, C.J.¹ Ward, J.M.² Hopwood, D.A.³

40
- 0025081416
- J. Cortés; S. F. Haydock; G. A. Roberts; D. J. Bevitt; P. F. Leadlay, Nature 1990, 348, 176.
- (1990) Nature , vol.348 , pp. 176
- Cortés, J.¹ Haydock, S.F.² Roberts, G.A.³ Bevitt, D.J.⁴ Leadlay, P.F.⁵

41
- 0026415106
- S. Donadio; M. J. Staver; J. B. McAlpine; S. J. Swanson; L. Katz, Science 1991, 252, 675.
- (1991) Science , vol.252 , pp. 675
- Donadio, S.¹ Staver, M.J.² McAlpine, J.B.³ Swanson, S.J.⁴ Katz, L.⁵

42
- 84906288992
- D. J. Bevitt; J. Cortés; S. F. Haydock; P. F. Leadlay, Eur. J. Biochem. 1992, 111, 51.
- (1992) Eur. J. Biochem , vol.111 , pp. 51
- Bevitt, D.J.¹ Cortés, J.² Haydock, S.F.³ Leadlay, P.F.⁴

43
- 0026559262
- S. Donadio; L. Katz, Gene 1992, 111, 51.
- (1992) Gene , vol.111 , pp. 51
- Donadio, S.¹ Katz, L.²

44
- 0025335890
- J. S. Tuan; J. M. Weber; M. J. Staver; J. O. Leung; S. Donadio; L. Katz, Gene 1990, 90, 21.
- (1990) Gene , vol.90 , pp. 21
- Tuan, J.S.¹ Weber, J.M.² Staver, M.J.³ Leung, J.O.⁴ Donadio, S.⁵ Katz, L.⁶

45
- 44049083124
- K. J. Weissman; R. Müller, ChemBioChem 2008, 9, 826.
- (2008) ChemBioChem , vol.9 , pp. 826
- Weissman, K.J.¹ Müller, R.²

46
- 0026697224
- P. Caffrey; D. J. Bevitt; J. Staunton; P. F. Leadlay, FEBS Lett. 1992, 304, 225.
- (1992) FEBS Lett , vol.304 , pp. 225
- Caffrey, P.¹ Bevitt, D.J.² Staunton, J.³ Leadlay, P.F.⁴

47
- 0029027352
- J. Cortés; K. E. H. Weismann; G. A. Roberts; M. J. B. Brown; J. Staunton; P. F. Leadlay, Science 1995, 268, 1487.
- (1995) Science , vol.268 , pp. 1487
- Cortés, J.¹ Weismann, K.E.H.² Roberts, G.A.³ Brown, M.J.B.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

48
- 0028857296
- C. M. Kao; G. Luo; L. Katz; D. E. Cane; C. Khosla, J. Am. Chem. Soc. 1995, 117, 9105.
- (1995) J. Am. Chem. Soc , vol.117 , pp. 9105
- Kao, C.M.¹ Luo, G.² Katz, L.³ Cane, D.E.⁴ Khosla, C.⁵

49
- 0029360426
- K. E. H. Weismann; J. Cortés; M. J. B. Brown; A. L. Cutter; J. Staunton; P. F. Leadlay, Chem. Biol. 1995, 2, 583.
- (1995) Chem. Biol , vol.2 , pp. 583
- Weismann, K.E.H.¹ Cortés, J.² Brown, M.J.B.³ Cutter, A.L.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

50
- 0032146228
- I. Böhm; I. E. Holzbaur; U. Hanefield; J. Cortés; J. Staunton; P. F. Leadlay, Chem. Biol. 1998, 5, 407.
- (1998) Chem. Biol , vol.5 , pp. 407
- Böhm, I.¹ Holzbaur, I.E.² Hanefield, U.³ Cortés, J.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

51
- 0029804299
- C. M. Kao; G. Luo; L. Katz; D. E. Cane; C. Khosla, J. Am. Chem. Soc. 1996, 118, 9184.
- (1996) J. Am. Chem. Soc , vol.118 , pp. 9184
- Kao, C.M.¹ Luo, G.² Katz, L.³ Cane, D.E.⁴ Khosla, C.⁵

52
- 0028857296
- C. M. Kao; G. Luo; L. Katz; D. E. Cane; C. Khosla, J. Am. Chem. Soc. 1995, 117, 9105.
- (1995) J. Am. Chem. Soc , vol.117 , pp. 9105
- Kao, C.M.¹ Luo, G.² Katz, L.³ Cane, D.E.⁴ Khosla, C.⁵

53
- 0030723673
- C. M. Kao; M. McPherson; R. N. McDaniel; H. Fu; D. E. Cane; C. Khosla, J. Am. Chem. Soc. 1997, 119, 11337.
- (1997) J. Am. Chem. Soc , vol.119 , pp. 11337
- Kao, C.M.¹ McPherson, M.² McDaniel, R.N.³ Fu, H.⁴ Cane, D.E.⁵ Khosla, C.⁶

54
- 0030902054
- R. McDaniel; C. M. Kao; H. Fu; P. Hevezi; C. Gustafsson; M. Betlach; G. Ashley; D. E. Cane; C. Khosla, J. Am. Chem. Soc. 1997, 119, 4309.
- (1997) J. Am. Chem. Soc , vol.119 , pp. 4309
- McDaniel, R.¹ Kao, C.M.² Fu, H.³ Hevezi, P.⁴ Gustafsson, C.⁵ Betlach, M.⁶ Ashley, G.⁷ Cane, D.E.⁸ Khosla, C.⁹

55
- 0031239838
- R. McDaniel; C. M. Kao; S. J. Hwang; D. E. Cane; C. Khosla, Chem. Biol. 1997, 4, 667.
- (1997) Chem. Biol , vol.4 , pp. 667
- McDaniel, R.¹ Kao, C.M.² Hwang, S.J.³ Cane, D.E.⁴ Khosla, C.⁵

56
- 0030266007
- M. Oliynyk; M. J. B. Brown; J. Cortés; J. Staunton; P. F. Leadlay, Chem. Biol. 1996, 3, 833.
- (1996) Chem. Biol , vol.3 , pp. 833
- Oliynyk, M.¹ Brown, M.J.B.² Cortés, J.³ Staunton, J.⁴ Leadlay, P.F.⁵

57
- 42549165756
- H. Zhang; Y. Wang; B. A. Pfeifer, Mol. Pharm. 2008, 5, 212.
- (2008) Mol. Pharm , vol.5 , pp. 212
- Zhang, H.¹ Wang, Y.² Pfeifer, B.A.³

58
- 84906286144
- S. C. Wenzel; R. Müller, Curr. Opin. Biotechnol. 2005, 16, 6828.
- (2005) Curr. Opin. Biotechnol , vol.16 , pp. 6828
- Wenzel, S.C.¹ Müller, R.²

59
- 0029087375
- M. J. B. Brown; J. Cortés; A. L. Cutter; P. F. Leadlay; J. Staunton, J. Chem. Soc. Chem. Commun. 1995, 1517.
- (1995) J. Chem. Soc. Chem. Commun , pp. 1517
- Brown, M.J.B.¹ Cortés, J.² Cutter, A.L.³ Leadlay, P.F.⁴ Staunton, J.⁵

60
- 0037435553
- G. F. Liou; J. Lau; D. E. Cane; C. Khosla, Biochemistry 2003, 42, 200.
- (2003) Biochemistry , vol.42 , pp. 200
- Liou, G.F.¹ Lau, J.² Cane, D.E.³ Khosla, C.⁴

61
- 18944399910
- H. Hong; A. N. Appleyard; A. P. Siskos; J. Carcia-Bernado; J. Staunton; P. F. Leadlay, FEBS J. 2005, 272, 2373.
- (2005) FEBS J , vol.272 , pp. 2373
- Hong, H.¹ Appleyard, A.N.² Siskos, A.P.³ Carcia-bernado, J.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

62
- 0037176911
- L. H. Østergaard; L. Kellenberger; J. Cortés; M. P. Roddis; M. Deacon; J. Staunton; P. F. Leadlay, Biochemistry 2002, 41, 2719.
- (2002) Biochemistry , vol.41 , pp. 2719
- Østergaard, L.H.¹ Kellenberger, L.² Cortés, J.³ Roddis, M.P.⁴ Deacon, M.⁵ Staunton, J.⁶ Leadlay, P.F.⁷

63
- 0004273864
- W. D. Celmer, J. Am. Chem. Soc. 1965, 87, 1799.
- (1965) J. Am. Chem. Soc , vol.87 , pp. 1799
- Celmer, W.D.¹

64
- 33947490731
- W. D. Celmer, J. Am. Chem. Soc. 1965, 87, 1801.
- (1965) J. Am. Chem. Soc , vol.87 , pp. 1801
- Celmer, W.D.¹

65
- 0032495764
- M. McPherson; C. Khosla; D. E. Cane, J. Am. Chem. Soc. 1998, 120, 3267.
- (1998) J. Am. Chem. Soc , vol.120 , pp. 3267
- McPherson, M.¹ Khosla, C.² Cane, D.E.³

66
- 0042307438
- P. Caffrey, ChemBioChem 2003, 4, 654.
- (2003) ChemBioChem , vol.4 , pp. 654
- Caffrey, P.¹

67
- 0037435603
- R. Reid; M. Piagentini; E. Rodriguez; G. Ashley; N. Viswanathan; J. Carney; D. V. Santi; C. R. Hutchinson; R. McDaniel, Biochemistry 2003, 42, 72.
- (2003) Biochemistry , vol.42 , pp. 72
- Reid, R.¹ Piagentini, M.² Rodriguez, E.³ Ashley, G.⁴ Viswanathan, N.⁵ Carney, J.⁶ Santi, D.V.⁷ Hutchinson, C.R.⁸ McDaniel, R.⁹

68
- 0026415106
- S. Donadio; M. J. Staver; J. B. McAlpine; S. J. Swanson; L. Katz, Science 1991, 252, 675.
- (1991) Science , vol.252 , pp. 675
- Donadio, S.¹ Staver, M.J.² McAlpine, J.B.³ Swanson, S.J.⁴ Katz, L.⁵

69
- 0028181428
- A. F. A. Marsden; P. Caffrey; J. P. Aparicio; M. S. Loughran; J. Staunton; P. F. Leadlay, Science 1994, 263, 378.
- (1994) Science , vol.263 , pp. 378
- Marsden, A.F.A.¹ Caffrey, P.² Aparicio, J.P.³ Loughran, M.S.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

70
- 0030678504
- K. J. Weissman; M. Timoney; M. Bycroft; P. Grice; U. Hanefield; J. Staunton; P. F. Leadlay, Biochemistry 1997, 36, 13849.
- (1997) Biochemistry , vol.36 , pp. 13849
- Weissman, K.J.¹ Timoney, M.² Bycroft, M.³ Grice, P.⁴ Hanefield, U.⁵ Staunton, J.⁶ Leadlay, P.F.⁷

71
- 0033117371
- I. E. Holzbauer; R. C. Harris; M. Bycroft; J. Cortés; C. Bisang; J. Staunton; B. A. M. Rudd; P. F. Leadlay, Chem. Biol. 1999, 6, 189.
- (1999) Chem. Biol , vol.6 , pp. 189
- Holzbauer, I.E.¹ Harris, R.C.² Bycroft, M.³ Cortés, J.⁴ Bisang, C.⁵ Staunton, J.⁶ Rudd, B.A.M.⁷ Leadlay, P.F.⁸

72
- 8344270313
- C. Y. Kim; V. Y. Alekseyev; A. Y. Chen; Y. Y. Tang; D. E. Cane; C. Khosla, Biochemistry 2004, 43, 13892.
- (2004) Biochemistry , vol.43 , pp. 13892
- Kim, C.Y.¹ Alekseyev, V.Y.² Chen, A.Y.³ Tang, Y.Y.⁴ Cane, D.E.⁵ Khosla, C.⁶

73
- 36048958284
- R. Castonguay; W. G. He; A. Y. Chen; C. Khosla; D. E. Cane, J. Am. Chem. Soc. 2007, 129, 13758.
- (2007) J. Am. Chem. Soc , vol.129 , pp. 13758
- Castonguay, R.¹ He, W.G.² Chen, A.Y.³ Khosla, C.⁴ Cane, D.E.⁵

74
- 34447547495
- A. Y. Chen; D. E. Cane; C. Khosla, Chem. Biol. 2007, 14, 784.
- (2007) Chem. Biol , vol.14 , pp. 784
- Chen, A.Y.¹ Cane, D.E.² Khosla, C.³

75
- 23444460405
- S. Weist; R. D. Süssmuth, Appl. Microbiol. Biotechnol. 2005, 68, 141.
- (2005) Appl. Microbiol. Biotechnol , vol.68 , pp. 141
- Weist, S.¹ Süssmuth, R.D.²

76
- 33947160920
- K. J. Weissman, Trends Biotechnol. 2007, 25, 139.
- (2007) Trends Biotechnol , vol.25 , pp. 139
- Weissman, K.J.¹

77
- 77956933919
- Structure and Mechanism of Fatty Acid Synthetase
- P. D. Boyer, Ed.; Academic Press: New York
- S. J. Wakil; J. K. Stoops, Structure and Mechanism of Fatty Acid Synthetase. In The Enzymes; P. D. Boyer, Ed.; Academic Press: New York, 1983; Vol. XVI, p 3.
- (1983) The Enzymes , vol.16 , pp. 3
- Wakil, S.J.¹ Stoops, J.K.²

78
- 0019888073
- J. K. Stoops; S. J. Wakil, J. Biol. Chem. 1981, 256, 5128.
- (1981) J. Biol. Chem , vol.256 , pp. 5128
- Stoops, J.K.¹ Wakil, S.J.²

79
- 0023664701
- J. K. Stoops; S. J. Wakil; E. C. Uberbacher; G. J. Bunick, J. Biol. Chem. 1987, 262, 10246.
- (1987) J. Biol. Chem , vol.262 , pp. 10246
- Stoops, J.K.¹ Wakil, S.J.² Uberbacher, E.C.³ Bunick, G.J.⁴

80
- 0029816829
- A. Witkowski; A. K. Joshi; S. Smith, Biochemistry 1996, 35, 10569.
- (1996) Biochemistry , vol.35 , pp. 10569
- Witkowski, A.¹ Joshi, A.K.² Smith, S.³

81
- 0031050460
- A. K. Joshi; A. Witkowski; S. Smith, Biochemistry 1997, 36, 2316.
- (1997) Biochemistry , vol.36 , pp. 2316
- Joshi, A.K.¹ Witkowski, A.² Smith, S.³

82
- 0032562216
- A. K. Joshi; A. Witkowski; S. Smith, Biochemistry 1998, 36, 2515.
- (1998) Biochemistry , vol.36 , pp. 2515
- Joshi, A.K.¹ Witkowski, A.² Smith, S.³

83
- 0032570557
- A. K. Joshi; V. S. Rangan; S. Smith, J. Biol. Chem. 1998, 273, 4937.
- (1998) J. Biol. Chem , vol.273 , pp. 4937
- Joshi, A.K.¹ Rangan, V.S.² Smith, S.³

84
- 0033597208
- A. Witlowski; A. K. Joshi; V. S. Rangan; A. M. Falick; H. E. Witkowska; S. Smith, J. Biol. Chem. 1999, 274, 11557.
- (1999) J. Biol. Chem , vol.274 , pp. 11557
- Witlowski, A.¹ Joshi, A.K.² Rangan, V.S.³ Falick, A.M.⁴ Witkowska, H.E.⁵ Smith, S.⁶

85
- 0035845638
- V. S. Rangan; A. K. Joshi; S. Smith, Biochemistry 2001, 40, 10792.
- (2001) Biochemistry , vol.40 , pp. 10792
- Rangan, V.S.¹ Joshi, A.K.² Smith, S.³

86
- 0037330531
- A. K. Joshi; V. S. Rangan; A. Witkowski; S. Smith, Chem. Biol. 2003, 10, 169.
- (2003) Chem. Biol , vol.10 , pp. 169
- Joshi, A.K.¹ Rangan, V.S.² Witkowski, A.³ Smith, S.⁴

87
- 33644697200
- T. Maier; S. Jenni; N. Ban, Science 2006, 311, 1258.
- (2006) Science , vol.311 , pp. 1258
- Maier, T.¹ Jenni, S.² Ban, N.³

88
- 51149098989
- T. Maier; N. Leibunggut; N. Ban, Science 2008, 321, 1315.
- (2008) Science , vol.321 , pp. 1315
- Maier, T.¹ Leibunggut, N.² Ban, N.³

89
- 22244466130
- S. W. White; J. Zheng; Y. M. Zhang; C. O. Rock, Annu. Rev. Biochem. 2005, 74, 791.
- (2005) Annu. Rev. Biochem , vol.74 , pp. 791
- White, S.W.¹ Zheng, J.² Zhang, Y.M.³ Rock, C.O.⁴

90
- 34247383568
- S. Jenni; M. Leibundgut; D. Boehringer; C. Frick; B. Mikolasek; N. Ban, Science 2007, 316, 254.
- (2007) Science , vol.316 , pp. 254
- Jenni, S.¹ Leibundgut, M.² Boehringer, D.³ Frick, C.⁴ Mikolasek, B.⁵ Ban, N.⁶

91
- 34147098650
- I. B. Lomakin; Y. Xiong; T. A. Steiz, Cell 2007, 129, 319.
- (2007) Cell , vol.129 , pp. 319
- Lomakin, I.B.¹ Xiong, Y.² Steiz, T.A.³

92
- 34247353309
- M. Leibundgut; S. Jenni; C. Frick; N. Ban, Science 2007, 316, 288.
- (2007) Science , vol.316 , pp. 288
- Leibundgut, M.¹ Jenni, S.² Frick, C.³ Ban, N.⁴

93
- 38049136859
- E. Plokson; C. J. Arthur; S. E. Evans; C. Williams; J. Crosby; T. J. Simpson; M. P. Crump, J. Biol. Chem. 2008, 283, 518.
- (2008) J. Biol. Chem , vol.283 , pp. 518
- Plokson, E.¹ Arthur, C.J.² Evans, S.E.³ Williams, C.⁴ Crosby, J.⁵ Simpson, T.J.⁶ Crump, M.P.⁷

94
- 36049041632
- G. Bunkoczi; S. Pasta; A. Joshi; X. Q. Wu; K. L. Kavanough; S. Smith; U. Opperman, Chem. Biol. 2007, 14, 1243.
- (2007) Chem. Biol , vol.14 , pp. 1243
- Bunkoczi, G.¹ Pasta, S.² Joshi, A.³ Wu, X.Q.⁴ Kavanough, K.L.⁵ Smith, S.⁶ Opperman, U.⁷

95
- 8144227950
- B. Chakravarty; Z. Gu; S. S. Chirala; S. J. Wakil; F. A. Quiocho, Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 15567.
- (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 15567
- Chakravarty, B.¹ Gu, Z.² Chirala, S.S.³ Wakil, S.J.⁴ Quiocho, F.A.⁵

96
- 34547672758
- C. W. Pemble L. C. Johnson; S. J. Kridel; W. T. Lowther, Nat. Struct. Mol. Biol. 2007, 14, 704.
- (2007) Nat. Struct. Mol. Biol , vol.14 , pp. 704
- Pemble, C.W.¹ Johnson, L.C.² Kridel, S.J.³ Lowther, W.T.⁴

97
- 57049083416
- M. Leibundgut; T. Maier; S. Jenni; N. Ban, Curr. Opin. Struct. Biol. 2008, 18, 714.
- (2008) Curr. Opin. Struct. Biol , vol.18 , pp. 714
- Leibundgut, M.¹ Maier, T.² Jenni, S.³ Ban, N.⁴

98
- 33644687879
- S. Smith, Science 2006, 311, 1251.
- (2006) Science , vol.311 , pp. 1251
- Smith, S.¹

99
- 33646053163
- C. A. Townsend; J. M. Crawford; T. Bililign, Chem. Biol. 2006, 13, 349.
- (2006) Chem. Biol , vol.13 , pp. 349
- Townsend, C.A.¹ Crawford, J.M.² Bililign, T.³

100
- 0027415391
- P. F. Leadlay; J. Staunton; J. F. Aparicio; D. J. Bevitt; P. Caffrey; J. Cortes; A. Marsden; G. A. Roberts, Biochem. Soc. Trans. 1993, 21, 218.
- (1993) Biochem. Soc. Trans , vol.21 , pp. 218
- Leadlay, P.F.¹ Staunton, J.² Aparicio, J.F.³ Bevitt, D.J.⁴ Caffrey, P.⁵ Cortes, J.⁶ Marsden, A.⁷ Roberts, G.A.⁸

101
- 0027318089
- G. A. Roberts; J. Staunton; P. F. Leadlay, Eur. J. Biochem. 1993, 214, 305.
- (1993) Eur. J. Biochem , vol.214 , pp. 305
- Roberts, G.A.¹ Staunton, J.² Leadlay, P.F.³

102
- 0028365063
- J. F. Aparicio; P. Caffrey; A. F. A. Marsden; J. Staunton; P. F. Leadlay, J. Biol. Chem. 1994, 269, 8524.
- (1994) J. Biol. Chem , vol.269 , pp. 8524
- Aparicio, J.F.¹ Caffrey, P.² Marsden, A.F.A.³ Staunton, J.⁴ Leadlay, P.F.⁵

103
- 0030065324
- J. Staunton; P. Caffrey; J. F. Aparicio; G. A. Roberts; S. S. Bethel; P. F. Leadlay, Nat. Struct. Biol. 1996, 3, 188.
- (1996) Nat. Struct. Biol , vol.3 , pp. 188
- Staunton, J.¹ Caffrey, P.² Aparicio, J.F.³ Roberts, G.A.⁴ Bethel, S.S.⁵ Leadlay, P.F.⁶

104
- 0029797581
- C. M. Kao; R. Pieper; D. E. Cane; C. Khosla, Biochemistry 1996, 35, 12363.
- (1996) Biochemistry , vol.35 , pp. 12363
- Kao, C.M.¹ Pieper, R.² Cane, D.E.³ Khosla, C.⁴

105
- 0032562129
- R. S. Gokhale; J. Lau; D. E. Cane; C. Khosla, Biochemistry 1998, 37, 2524.
- (1998) Biochemistry , vol.37 , pp. 2524
- Gokhale, R.S.¹ Lau, J.² Cane, D.E.³ Khosla, C.⁴

106
- 0041412707
- R. W. Broadhurst; D. Nietlispach; M. P. Wheatcroft; P. F. Leadlay; K. J. Weissman, Chem. Biol. 2003, 10, 723.
- (2003) Chem. Biol , vol.10 , pp. 723
- Broadhurst, R.W.¹ Nietlispach, D.² Wheatcroft, M.P.³ Leadlay, P.F.⁴ Weissman, K.J.⁵

107
- 0344443723
- C. M. Squire; R. J. M. Goss; H. Hong; P. F. Leadlay; J. Staunton, ChemBioChem 2003, 4, 1225.
- (2003) ChemBioChem , vol.4 , pp. 1225
- Squire, C.M.¹ Goss, R.J.M.² Hong, H.³ Leadlay, P.F.⁴ Staunton, J.⁵

108
- 0031239838
- R. Mc.Daniel; C. M. Kao; S. J. Hwang; C. Khosla, Chem. Biol. 1997, 4, 667.
- (1997) Chem. Biol , vol.4 , pp. 667
- McDaniel, R.¹ Kao, C.M.² Hwang, S.J.³ Khosla, C.⁴

109
- 33644931877
- K. J. Weissman, ChemBioChem 2006, 7, 485.
- (2006) ChemBioChem , vol.7 , pp. 485
- Weissman, K.J.¹

110
- 33748577348
- K. J. Weissman, ChemBioChem 2006, 7, 1334.
- (2006) ChemBioChem , vol.7 , pp. 1334
- Weissman, K.J.¹

111
- 34547933299
- V. Y. Alekseyev; C. W. Liu; D. E. Cane; J. D. Puglisi; C. Khosla, Protein Sci. 2007, 16, 2093.
- (2007) Protein Sci , vol.16 , pp. 2093
- Alekseyev, V.Y.¹ Liu, C.W.² Cane, D.E.³ Puglisi, J.D.⁴ Khosla, C.⁵

112
- 34447516335
- Y. Y. Tang; A. Y. Chen; C. Y. Kim; D. E. Cane; C. Khosla, Chem. Biol. 2007, 14, 931.
- (2007) Chem. Biol , vol.14 , pp. 931
- Tang, Y.Y.¹ Chen, A.Y.² Kim, C.Y.³ Cane, D.E.⁴ Khosla, C.⁵

113
- 33746776204
- Y. Tang; C. Y. Kim; I. I. Mathews; D. E. Cane; C. Khosla, Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 11124.
- (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 11124
- Tang, Y.¹ Kim, C.Y.² Mathews, I.I.³ Cane, D.E.⁴ Khosla, C.⁵

114
- 33645962845
- A. T. Keatinge-Clay; R. M. Stroud, Structure 2006, 14, 737.
- (2006) Structure , vol.14 , pp. 737
- Keatinge-clay, A.T.¹ Stroud, R.M.²

115
- 34547945950
- A. T. Keatinge-Clay, Chem. Biol. 2007, 14, 898.
- (2007) Chem. Biol , vol.14 , pp. 898
- Keatinge-clay, A.T.¹

116
- 34247326876
- C. D. Richter; D. A. Stanmore; R. N. Miguel; M. C. Moncrieffe; L. Tran; S. Brewerton; F. Meersman; R. W. Broadhurst; K. J. Weissman, FEBS J. 2007, 274, 2196.
- (2007) FEBS J , vol.274 , pp. 2196
- Richter, C.D.¹ Stanmore, D.A.² Miguel, R.N.³ Moncrieffe, M.C.⁴ Tran, L.⁵ Brewerton, S.⁶ Meersman, F.⁷ Broadhurst, R.W.⁸ Weissman, K.J.⁹

117
- 59649102440
- E. J. Brignole; S. Smith; F. J. Asturias, Nat. Struct. Mol. Biol. 2009, 16, 190.
- (2009) Nat. Struct. Mol. Biol , vol.16 , pp. 190
- Brignole, E.J.¹ Smith, S.² Asturias, F.J.³

118
- 0035675996
- P. F. Leadlay; J. Staunton; M. Oliynyk; C. Bisang; J. Cortés; E. Frost; Z. A. Hughes-Thomas; M. A. Jones; S. G. Kendrew; J. B. Lester; P. F. Long; H. A. I. McArthur; E. L. McCormick; Z. Oliynyk; C. B. W. Stark; C. J. Wilkinson, J. Indus. Microb. Biotechnol. 2001, 27, 360.
- (2001) J. Indus. Microb. Biotechnol , vol.27 , pp. 360
- Leadlay, P.F.¹ Staunton, J.² Oliynyk, M.³ Bisang, C.⁴ Cortés, J.⁵ Frost, E.⁶ Hughes-thomas, Z.A.⁷ Jones, M.A.⁸ Kendrew, S.G.⁹ Lester, J.B.¹⁰ Long, P.F.¹¹ McArthur, H.A.I.¹² McCormick, E.L.¹³ Oliynyk, Z.¹⁴ Stark, C.B.W.¹⁵ Wilkinson, C.J.¹⁶

119
- 0141789847
- M. Oliynyk; C. B. W. Stark; A. Bhatt; M. A. Jones; Z. A. Hughes-Thomas; C. Wilkinson; Z. Oliynyk; Y. Demydchuk; J. Staunton; P. F. Leadlay, Mol. Microbiol. 2003, 49, 1179.
- (2003) Mol. Microbiol , vol.49 , pp. 1179
- Oliynyk, M.¹ Stark, C.B.W.² Bhatt, A.³ Jones, M.A.⁴ Hughes-thomas, Z.A.⁵ Wilkinson, C.⁶ Oliynyk, Z.⁷ Demydchuk, Y.⁸ Staunton, J.⁹ Leadlay, P.F.¹⁰

120
- 0029098323
- T. Schwecke; J. F. Aparicio; I. Molnár; A. König; L. E. Khaw; S. F. Haydock; M. Oliynyk; P. Caffrey; J. Cortés; J. B. Lester; G. A. Böhm; J. Staunton; P. F. Leadlay, Proc. Natl. Acad. Sci. U.S.A. 1995, 92, 7839.
- (1995) Proc. Natl. Acad. Sci. U.S.A , vol.92 , pp. 7839
- Schwecke, T.¹ Aparicio, J.F.² Molnár, I.³ König, A.⁴ Khaw, L.E.⁵ Haydock, S.F.⁶ Oliynyk, M.⁷ Caffrey, P.⁸ Cortés, J.⁹ Lester, J.B.¹⁰ Böhm, G.A.¹¹ Staunton, J.¹² Leadlay, P.F.¹³

121
- 0029872079
- J. F. Aparicio; I. Molnár; T. Schwecke; A. König; S. F. Haydock; L. E. Khaw; J. Staunton; P. F. Leadlay, Gene 1996, 169, 9.
- (1996) Gene , vol.169 , pp. 9
- Aparicio, J.F.¹ Molnár, I.² Schwecke, T.³ König, A.⁴ Haydock, S.F.⁵ Khaw, L.E.⁶ Staunton, J.⁷ Leadlay, P.F.⁸

122
- 10744229306
- T. P. Stinear; A. Mve-Obiang; P. L. C. Small; W. Frigui; M. L. Pryor; R. Brosch; G. A. Jenkin; P. D. R. Johnson; J. K. Davies; R. E. Lee; S. Adusumilli; T. Garnier; S. F. Haydock; P. F. Leadlay; S. T. Cole, Proc. Natl. Acad. Sci. U.S A. 2004, 191, 1345.
- (2004) Proc. Natl. Acad. Sci. U.S A , vol.191 , pp. 1345
- Stinear, T.P.¹ Mve-obiang, A.² Small, P.L.C.³ Frigui, W.⁴ Pryor, M.L.⁵ Brosch, R.⁶ Jenkin, G.A.⁷ Johnson, P.D.R.⁸ Davies, J.K.⁹ Lee, R.E.¹⁰ Adusumilli, S.¹¹ Garnier, T.¹² Haydock, S.F.¹³ Leadlay, P.F.¹⁴ Cole, S.T.¹⁵

123
- 42449158575
- C. P. Ridley; H. Y. Lee; C. Khosla, Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 4595.
- (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 4595
- Ridley, C.P.¹ Lee, H.Y.² Khosla, C.³

124
- 44249084709
- H. Hong; C. Demangel; S. J. Pidot; P. F. Leadlay; T. Stinear, Nat. Prod. Rep. 2008, 25, 447.
- (2008) Nat. Prod. Rep , vol.25 , pp. 447
- Hong, H.¹ Demangel, C.² Pidot, S.J.³ Leadlay, P.F.⁴ Stinear, T.⁵

125
- 84906286145
- Polyketide Biosynthesis, Polyethers
- T. D. Begley, Ed.; John Wiley and Sons, doi: 10.1002/9780470048672.wecb460
- A. M. Hill, Polyketide Biosynthesis, Polyethers. In Wiley Encyclopedia of Chemical Biology; T. D. Begley, Ed.; John Wiley and Sons, 2008, doi: 10.1002/9780470048672.wecb460.
- (2008) Wiley Encyclopedia of Chemical Biology
- Hill, A.M.¹

126
- 0001111131
- F. G. Riddell, Chem. Br. 1992, 28, 533.
- (1992) Chem. Br , vol.28 , pp. 533
- Riddell, F.G.¹

127
- 34250309503
- B. M. Harvey; T. Mironenko; Y. H. Sun; H. Hong; Z. X. Deng; P. F. Leadlay; K. J. Weissman; S. F. Haydock, Chem. Biol. 2007, 14, 703.
- (2007) Chem. Biol , vol.14 , pp. 703
- Harvey, B.M.¹ Mironenko, T.² Sun, Y.H.³ Hong, H.⁴ Deng, Z.X.⁵ Leadlay, P.F.⁶ Weissman, K.J.⁷ Haydock, S.F.⁸

128
- 0037846116
- Y. Sun; X. Zhou; H. Dong; G. Tu; M. Wang; B. Wang; Z. Deng, Chem. Biol. 2003, 10, 431.
- (2003) Chem. Biol , vol.10 , pp. 431
- Sun, Y.¹ Zhou, X.² Dong, H.³ Tu, G.⁴ Wang, M.⁵ Wang, B.⁶ Deng, Z.⁷

129
- 33748528639
- T. Liu; D. You; C. Valenzano; Y. Sun; J. Li; Q. Yu; X. Zhou; D. E. Cane; Z. Deng, Chem. Biol. 2006, 13, 945.
- (2006) Chem. Biol , vol.13 , pp. 945
- Liu, T.¹ You, D.² Valenzano, C.³ Sun, Y.⁴ Li, J.⁵ Yu, Q.⁶ Zhou, X.⁷ Cane, D.E.⁸ Deng, Z.⁹

130
- 46649112563
- Y. Demydchuk; Y. H. Sun; H. Hong; J. Staunton; J. B. Spencer; P. F. Leadlay, ChemBioChem 2008, 9, 1136.
- (2008) ChemBioChem , vol.9 , pp. 1136
- Demydchuk, Y.¹ Sun, Y.H.² Hong, H.³ Staunton, J.⁴ Spencer, J.B.⁵ Leadlay, P.F.⁶

131
- 0013294451
- B. Shen; H.-J. Kwon, Chem. Rec. 2002, 2, 389.
- (2002) Chem. Rec , vol.2 , pp. 389
- Shen, B.¹ Kwon, H.-J.²

132
- 0037162840
- H.-J. Kwon; W. C. Smith; J. Scharon; S. H. Hwang; M. J. Kurth; B. Shen, Science 2002, 297, 1327.
- (2002) Science , vol.297 , pp. 1327
- Kwon, H.-J.¹ Smith, W.C.² Scharon, J.³ Hwang, S.H.⁴ Kurth, M.J.⁵ Shen, B.⁶

133
- 0141473478
- Polyether Antibiotics - Biosynthesis
- J. W. Corcoran, Ed., Springer-Verlag: New York
- J. W. Westley, Polyether Antibiotics - Biosynthesis. In Antibiotics IV; J. W. Corcoran, Ed., Springer-Verlag: New York; 1981, pp 41-73.
- (1981) Antibiotics IV , pp. 41-73
- Westley, J.W.¹

134
- 0020424744
- D. E. Cane; T. C. Liang; H. C. Hasler, J. Am. Chem. Soc. 1982, 104, 7274.
- (1982) J. Am. Chem. Soc , vol.104 , pp. 7274
- Cane, D.E.¹ Liang, T.C.² Hasler, H.C.³

135
- 0020774684
- D. E. Cane; W. D. Celmer; J. W. Westley, J. Am. Chem. Soc. 1983, 105, 3594.
- (1983) J. Am. Chem. Soc , vol.105 , pp. 3594
- Cane, D.E.¹ Celmer, W.D.² Westley, J.W.³

136
- 33748550675
- B. M. Harvey; H. Hong; M. A. Jones; Z. A. Hughes-Thomas; R. M. Goss; M. L. Heathcote; V. M. Bolanos-Garcia; W. Kroutil; J. Staunton; P. F. Leadlay; J. B. Spencer, ChemBioChem 2006, 7, 1435.
- (2006) ChemBioChem , vol.7 , pp. 1435
- Harvey, B.M.¹ Hong, H.² Jones, M.A.³ Hughes-thomas, Z.A.⁴ Goss, R.M.⁵ Heathcote, M.L.⁶ Bolanos-garcia, V.M.⁷ Kroutil, W.⁸ Staunton, J.⁹ Leadlay, P.F.¹⁰ Spencer, J.B.¹¹

137
- 27744442699
- A. Bhatt; C. B. W. Stark; B. M. Harvey; A. R. Gallimore; Y. A. Demydchuk; J. B. Spencer; J. Staunton; P. F. Leadlay, Angew. Chem. Int. Ed. 2005, 44, 7075.
- (2005) Angew. Chem. Int. Ed , vol.44 , pp. 7075
- Bhatt, A.¹ Stark, C.B.W.² Harvey, B.M.³ Gallimore, A.R.⁴ Demydchuk, Y.A.⁵ Spencer, J.B.⁶ Staunton, J.⁷ Leadlay, P.F.⁸

138
- 33646059885
- A. R. Gallimore; C. B. W. Stark; A. Bhatt; B. M. Harvey; Y. Demydchuck; V. Bolanos-Garcia; D. J. Fowler; J. Staunton; P. F. Leadlay; J. B. Spencer, Chem. Biol. 2006, 13, 453.
- (2006) Chem. Biol , vol.13 , pp. 453
- Gallimore, A.R.¹ Stark, C.B.W.² Bhatt, A.³ Harvey, B.M.⁴ Demydchuck, Y.⁵ Bolanos-garcia, V.⁶ Fowler, D.J.⁷ Staunton, J.⁸ Leadlay, P.F.⁹ Spencer, J.B.¹⁰

139
- 0344361923
- J. E. Baldwin, J. Chem. Soc. Chem. Commun. 1976, 11, 734.
- (1976) J. Chem. Soc. Chem. Commun , vol.11 , pp. 734
- Baldwin, J.E.¹

140
- 84906286146
- W. Hüttel; J. E. Davies; J. B. Spencer; P. F. Leadlay, Unpublished results
- W. Hüttel; J. E. Davies; J. B. Spencer; P. F. Leadlay, Unpublished results.

141
- 0033619244
- C. Bisang; P. F. Long; J. Cortés; J. Westcott; J. Crosby; A. L. Matharu; R. J. Cox; T. J. Simpson; J. Staunton; P. F. Leadlay, Nature 1999, 401, 502.
- (1999) Nature , vol.401 , pp. 502
- Bisang, C.¹ Long, P.F.² Cortés, J.³ Westcott, J.⁴ Crosby, J.⁵ Matharu, A.L.⁶ Cox, R.J.⁷ Simpson, T.J.⁸ Staunton, J.⁹ Leadlay, P.F.¹⁰

142
- 0036223415
- P. F. Long; C. J. Wilkinson; C. P. Bisang; J. Cortés; N. Dunster; M. Oliynyk; E. McCormick; H. McArthur; C. Mendez; J. A. Salas; J. Staunton; P. F. Leadlay, Mol. Microbiol. 2002, 43, 1215.
- (2002) Mol. Microbiol , vol.43 , pp. 1215
- Long, P.F.¹ Wilkinson, C.J.² Bisang, C.P.³ Cortés, J.⁴ Dunster, N.⁵ Oliynyk, M.⁶ McCormick, E.⁷ McArthur, H.⁸ Mendez, C.⁹ Salas, J.A.¹⁰ Staunton, J.¹¹ Leadlay, P.F.¹²

143
- 0026059342
- A. G. DiLella; R. J. Craig, Biochemistry 1991, 30, 8512.
- (1991) Biochemistry , vol.30 , pp. 8512
- DiLella, A.G.¹ Craig, R.J.²

144
- 0028360374
- E. J. Brown; M. W. Albers; T. B. Shin; K. Ichikawa; C. T. Keith; W. S. Cane; S. L. Schreiber, Nature 1994, 369, 756.
- (1994) Nature , vol.369 , pp. 756
- Brown, E.J.¹ Albers, M.W.² Shin, T.B.³ Ichikawa, K.⁴ Keith, C.T.⁵ Cane, W.S.⁶ Schreiber, S.L.⁷

145
- 0035804386
- P. A. S. Lowden; B. Wilkinson; G. A. Böhm; S. Handa; H. G. Floss; P. F. Leadlay; J. Staunton, Angew. Chem. Int. Ed. 2001, 40, 777.
- (2001) Angew. Chem. Int. Ed , vol.40 , pp. 777
- Lowden, P.A.S.¹ Wilkinson, B.² Böhm, G.A.³ Handa, S.⁴ Floss, H.G.⁵ Leadlay, P.F.⁶ Staunton, J.⁷

146
- 0025973839
- N. L. Paiva; A. L. Demain; M. F. Roberts, J. Nat. Prod. 1991, 54, 167.
- (1991) J. Nat. Prod , vol.54 , pp. 167
- Paiva, N.L.¹ Demain, A.L.² Roberts, M.F.³

147
- 0030872295
- A. König; T. Schwecke; I. Molnár; G. A. Böhm; P. A. S. Lowden; J. Staunton; P. F. Leadlay, Eur. J. Biochem. 1997, 247, 526.
- (1997) Eur. J. Biochem , vol.247 , pp. 526
- König, A.¹ Schwecke, T.² Molnár, I.³ Böhm, G.A.⁴ Lowden, P.A.S.⁵ Staunton, J.⁶ Leadlay, P.F.⁷

148
- 0029883934
- I. Molnár; J. F. Aparicio; S. F. Haydock; L. E. Khaw; T. Schwecke; A. König; J. Staunton; P. F. Leadlay, Gene 1996, 169, 1.
- (1996) Gene , vol.169 , pp. 1
- Molnár, I.¹ Aparicio, J.F.² Haydock, S.F.³ Khaw, L.E.⁴ Schwecke, T.⁵ König, A.⁶ Staunton, J.⁷ Leadlay, P.F.⁸

149
- 2642591970
- L. E. Khaw; G. A. Böhm; S. Metcalfe; J. Staunton; P. F. Leadlay, J. Bacteriol. 1998, 180, 809.
- (1998) J. Bacteriol , vol.180 , pp. 809
- Khaw, L.E.¹ Böhm, G.A.² Metcalfe, S.³ Staunton, J.⁴ Leadlay, P.F.⁵

150
- 33645392725
- G. J. Gatto, Jr.; M. T. Boyne; N. L. Kelleher; C. T. Walsh, J. Am. Chem. Soc. 2006, 128, 3838.
- (2006) J. Am. Chem. Soc , vol.128 , pp. 3838
- Gatto Jr., G.J.¹ Boyne, M.T.² Kelleher, N.L.³ Walsh, C.T.⁴

151
- 4544267423
- M. A. Gregory; S. Gaisser; R. E. Lill; H. Hong; R. M. Sheridan; B. Wilkinson; H. Petkovic; A. J. Weston; I. Carletti; H.-L. Lee; J. Staunton; P. F. Leadlay, Angew. Chem. Int. Ed. 2004, 43, 2551.
- (2004) Angew. Chem. Int. Ed , vol.43 , pp. 2551
- Gregory, M.A.¹ Gaisser, S.² Lill, R.E.³ Hong, H.⁴ Sheridan, R.M.⁵ Wilkinson, B.⁶ Petkovic, H.⁷ Weston, A.J.⁸ Carletti, I.⁹ Lee, H.-L.¹⁰ Staunton, J.¹¹ Leadlay, P.F.¹²

152
- 33749238417
- M. A. Gregory; H. Hong; R. E. Lill; S. Gaisser; H. Petkovic; L. Low; L. S. Sheehan; I. Carletti; S. J. Ready; M. J. Ward; A. L. Kaya; A. J. Weston; I. R. Challis; P. F. Leadlay; C. J. Martin; B. Wilkinson; R. M. Sheridan, Org. Biomol. Chem. 2006, 4, 3565.
- (2006) Org. Biomol. Chem , vol.4 , pp. 3565
- Gregory, M.A.¹ Hong, H.² Lill, R.E.³ Gaisser, S.⁴ Petkovic, H.⁵ Low, L.⁶ Sheehan, L.S.⁷ Carletti, I.⁸ Ready, S.J.⁹ Ward, M.J.¹⁰ Kaya, A.L.¹¹ Weston, A.J.¹² Challis, I.R.¹³ Leadlay, P.F.¹⁴ Martin, C.J.¹⁵ Wilkinson, B.¹⁶ Sheridan, R.M.¹⁷

153
- 23044465228
- M. A. Gregory; H. Petkovic; R. E. Lill; S. J. Moss; B. Wilkinson; S. Gaisser; P. F. Leadlay; R. M. Sheridan, Angew. Chem. Int. Ed. 2005, 44, 4757.
- (2005) Angew. Chem. Int. Ed , vol.44 , pp. 4757
- Gregory, M.A.¹ Petkovic, H.² Lill, R.E.³ Moss, S.J.⁴ Wilkinson, B.⁵ Gaisser, S.⁶ Leadlay, P.F.⁷ Sheridan, R.M.⁸

154
- 3042748791
- J. M. Cassady; K. K. Chan; H. G. Floss; E. Leistner, Chem. Pharm. Bull. 2004, 52, 1.
- (2004) Chem. Pharm. Bull , vol.52 , pp. 1
- Cassady, J.M.¹ Chan, K.K.² Floss, H.G.³ Leistner, E.⁴

155
- 14844356959
- H. G. Floss; T.-W. Yu, Chem. Rev. 2005, 105, 621.
- (2005) Chem. Rev , vol.105 , pp. 621
- Floss, H.G.¹ Yu, T.-W.²

156
- 13144258781
- P. R. August; L. Tang; Y. J. Yoon; S. Ning; R. Müller; T.-W. Yu; M. Taylor; D. Hoffman; C.-G. Kim; X. Zhang; C. R. Hutchinson; H. G. Floss, Chem. Biol. 1998, 5, 69.
- (1998) Chem. Biol , vol.5 , pp. 69
- August, P.R.¹ Tang, L.² Yoon, Y.J.³ Ning, S.⁴ Müller, R.⁵ Yu, T.-W.⁶ Taylor, M.⁷ Hoffman, D.⁸ Kim, C.-G.⁹ Zhang, X.¹⁰ Hutchinson, C.R.¹¹ Floss, H.G.¹²

157
- 0032519914
- T. Schupp; C. Toupet; N. Engel; S. Goff, FEMS Microbiol. Lett. 1998, 159, 201.
- (1998) FEMS Microbiol. Lett , vol.159 , pp. 201
- Schupp, T.¹ Toupet, C.² Engel, N.³ Goff, S.⁴

158
- 0041691117
- K. Watanabe; M. A. Rude; C. T. Walsh; C. Khosla, Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 9774.
- (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 9774
- Watanabe, K.¹ Rude, M.A.² Walsh, C.T.³ Khosla, C.⁴

159
- 23844557104
- J. Xu; E. Wan; C.-J. Tam; H. G. Floss, Microbiology 2005, 151, 2515.
- (2005) Microbiology , vol.151 , pp. 2515
- Xu, J.¹ Wan, E.² Tam, C.-J.³ Floss, H.G.⁴

160
- 0033529935
- T.-W. Yu; Y. Shen; Y. Doi-Katayama; L. Tang; C. Park; B. S. Moore; C. R. Hutchison; H. G. Floss, Proc. Natl. Acad. Sci. U.S.A. 1996, 96, 9051.
- (1996) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 9051
- Yu, T.-W.¹ Shen, Y.² Doi-katayama, Y.³ Tang, L.⁴ Park, C.⁵ Moore, B.S.⁶ Hutchison, C.R.⁷ Floss, H.G.⁸

161
- 0033376447
- A. Stratmann; C. Toupet; W. Schilling; R. Traber; L. Oberer; T. Schupp, Microbiology 1999, 145, 3365.
- (1999) Microbiology , vol.145 , pp. 3365
- Stratmann, A.¹ Toupet, C.² Schilling, W.³ Traber, R.⁴ Oberer, L.⁵ Schupp, T.⁶

162
- 0038183856
- A. El Sayed; J. Hothersall; S. M. Cooper; E. Stephens; T. J. Simpson; C. M. Thomas, Chem. Biol. 2003, 10, 419.
- (2003) Chem. Biol , vol.10 , pp. 419
- El Sayed, A.¹ Hothersall, J.² Cooper, S.M.³ Stephens, E.⁴ Simpson, T.J.⁵ Thomas, C.M.⁶

163
- 0037195174
- J. Piel, Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 14002.
- (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 14002
- Piel, J.¹

164
- 0347717826
- J. Piel; G. P. Wen; M. Platzer; D. Q. Hui, ChemBioChem 2004, 5, 93.
- (2004) ChemBioChem , vol.5 , pp. 93
- Piel, J.¹ Wen, G.P.² Platzer, M.³ Hui, D.Q.⁴

165
- 33846807734
- R. A. Butcher; F. C. Schroeder; M. A. Fisbach; P. D. Straight; R. Kolter; C. T. Walsh; J. Clardy, Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 1506.
- (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 1506
- Butcher, R.A.¹ Schroeder, F.C.² Fisbach, M.A.³ Straight, P.D.⁴ Kolter, R.⁵ Walsh, C.T.⁶ Clardy, J.⁷

166
- 36048989307
- J. Moldenhauer; X. H. Chen; R. Borriss; J. Piel, Angew. Chem. Int. Ed. 2007, 46, 8195.
- (2007) Angew. Chem. Int. Ed , vol.46 , pp. 8195
- Moldenhauer, J.¹ Chen, X.H.² Borriss, R.³ Piel, J.⁴

167
- 14844301665
- A. S. Rahman; J. Hothersall; J. Crosby; T. J. Simpson; C. M. Thomas, J. Biol. Chem. 2005, 280, 6399.
- (2005) J. Biol. Chem , vol.280 , pp. 6399
- Rahman, A.S.¹ Hothersall, J.² Crosby, J.³ Simpson, T.J.⁴ Thomas, C.M.⁵

168
- 64049116672
- Polyketide Biosynthesis, Fungi
- T. D. Begley, Ed.; John Wiley and Sons, doi: 10.1002/9780470048672.wecb458
- T. J. Simpson; R. J. Cox, Polyketide Biosynthesis, Fungi. In Wiley Encyclopedia of Chemical Biology; T. D. Begley, Ed.; John Wiley and Sons, 2008, doi: 10.1002/9780470048672.wecb458.
- (2008) Wiley Encyclopedia of Chemical Biology
- Simpson, T.J.¹ Cox, R.J.²

169
- 37049087634
- F. M. Martin; T. J. Simpson, J. Chem. Soc. Perkin Trans. I 1989, 207.
- (1989) J. Chem. Soc. Perkin Trans , vol.1 , pp. 207
- Martin, F.M.¹ Simpson, T.J.²

170
- 34250776587
- J. Wu; S. M. Cooper; R. J. Cox; J. Crosby; M. P. Crump; J. Hothersall; T. J. Simpson; C. M. Thomas; C. L. Willis, Chem. Commun. 2007, 2040.
- (2007) Chem. Commun , pp. 2040
- Wu, J.¹ Cooper, S.M.² Cox, R.J.³ Crosby, J.⁴ Crump, M.P.⁵ Hothersall, J.⁶ Simpson, T.J.⁷ Thomas, C.M.⁸ Willis, C.L.⁹

171
- 34447532448
- J. Hothersall; J. Wu; A. S. Ratiman; J. A. Shields; J. Haddock; N. Johnson; S. M. Cooper; E. R. Stephens; R. J. Cox; J. Cosby; C. L. Willis; T. J. Simpson; C. M. Thomas, J. Biol. Chem. 2007, 282, 15451.
- (2007) J. Biol. Chem , vol.282 , pp. 15451
- Hothersall, J.¹ Wu, J.² Ratiman, A.S.³ Shields, J.A.⁴ Haddock, J.⁵ Johnson, N.⁶ Cooper, S.M.⁷ Stephens, E.R.⁸ Cox, R.J.⁹ Cosby, J.¹⁰ Willis, C.L.¹¹ Simpson, T.J.¹² Thomas, C.M.¹³

172
- 15444381232
- S. M. Cooper; R. J. Cox; J. Crosby; M. P. Crump; J. Hothersall; W. Laosripaiboon; T. J. Simpson; C. M. Thomas, Chem. Commun. 2005, 1179.
- (2005) Chem. Commun , pp. 1179
- Cooper, S.M.¹ Cox, R.J.² Crosby, J.³ Crump, M.P.⁴ Hothersall, J.⁵ Laosripaiboon, W.⁶ Simpson, T.J.⁷ Thomas, C.M.⁸

173
- 22544461948
- S. M. Cooper; W. Laosripaiboon; A. S. Rahman; J. Hothersall; A. K. El-Sayed; C. Winfield; J. Crosby; R. J. Cox; T. J. Simpson; C. M. Thomas, Chem. Biol. 2005, 12, 825.
- (2005) Chem. Biol , vol.12 , pp. 825
- Cooper, S.M.¹ Laosripaiboon, W.² Rahman, A.S.³ Hothersall, J.⁴ El-sayed, A.K.⁵ Winfield, C.⁶ Crosby, J.⁷ Cox, R.J.⁸ Simpson, T.J.⁹ Thomas, C.M.¹⁰

174
- 49249099787
- J. Wu; J. Hothersall; C. Mazzetti; Y. O'Connel; J. A. Shields; A. S. Rahman; R. J. Cox; J. Crosby; T. J. Simpson; C. M. Thomas; C. L. Willis, ChemBioChem 2008, 9, 1500.
- (2008) ChemBioChem , vol.9 , pp. 1500
- Wu, J.¹ Hothersall, J.² Mazzetti, C.³ O'Connel, Y.⁴ Shields, J.A.⁵ Rahman, A.S.⁶ Cox, R.J.⁷ Crosby, J.⁸ Simpson, T.J.⁹ Thomas, C.M.¹⁰ Willis, C.L.¹¹

175
- 0032514668
- Y. Xue; L. Zhao; H.-W. Liu; D. H. Sherman, Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 12111.
- (1998) Proc. Natl. Acad. Sci. U.S.A , vol.95 , pp. 12111
- Xue, Y.¹ Zhao, L.² Liu, H.-W.³ Sherman, D.H.⁴

176
- 28244440471
- J. Wu; W. He; C. Khosla; D. E. Cane, Angew. Chem. Int. Ed. 2005, 44, 7557.
- (2005) Angew. Chem. Int. Ed , vol.44 , pp. 7557
- Wu, J.¹ He, W.² Khosla, C.³ Cane, D.E.⁴

177
- 0034598743
- Y. Xue; D. H. Sherman, Nature 2000, 403, 571.
- (2000) Nature , vol.403 , pp. 571
- Xue, Y.¹ Sherman, D.H.²

178
- 0035068571
- M. L. Heathcote; J. Staunton; P. F. Leadlay, Chem. Biol. 2001, 8, 207.
- (2001) Chem. Biol , vol.8 , pp. 207
- Heathcote, M.L.¹ Staunton, J.² Leadlay, P.F.³

179
- 84906297211
- B. J. Beck; Y. J. Yoon; K. A. Reynolds; D. H. Sherman, Chem. Biol. 2002, 7, 907.
- (2002) Chem. Biol , vol.7 , pp. 907
- Beck, B.J.¹ Yoon, Y.J.² Reynolds, K.A.³ Sherman, D.H.⁴

180
- 0035989968
- I. Thomas; C. J. Martin; C. J. Wilkinson; J. Staunton; P. F. Leadlay, Chem. Biol. 2002, 9, 781.
- (2002) Chem. Biol , vol.9 , pp. 781
- Thomas, I.¹ Martin, C.J.² Wilkinson, C.J.³ Staunton, J.⁴ Leadlay, P.F.⁵

181
- 20444455807
- C. C. Aldrich; B. J. Beck; R. A. Fecik; D. H. Sherman, J. Am. Chem. Soc. 2005, 127, 8441.
- (2005) J. Am. Chem. Soc , vol.127 , pp. 8441
- Aldrich, C.C.¹ Beck, B.J.² Fecik, R.A.³ Sherman, D.H.⁴

182
- 34547953900
- J. Kittendorf; B. J. Beck; T. J. Buchholz; W. Seufert; D. H. Sherman, Chem. Biol. 2007, 14, 944.
- (2007) Chem. Biol , vol.14 , pp. 944
- Kittendorf, J.¹ Beck, B.J.² Buchholz, T.J.³ Seufert, W.⁴ Sherman, D.H.⁵

183
- 7744235042
- S. J. Moss; C. J. Martin; B. Wilkinson, Nat. Prod. Rep. 2004, 21, 575.
- (2004) Nat. Prod. Rep , vol.21 , pp. 575
- Moss, S.J.¹ Martin, C.J.² Wilkinson, B.³

184
- 1142281943
- C. Olano; B. Wilkinson; C. Sánchez; S. J. Moss; R. Sheridan; V. Math; A. J. Weston; A. F. Braña; C. J. Martin; M. Oliynyk; C. Méndez; P. F. Leadlay; J. A. Salas, Chem. Biol. 2004, 11, 87.
- (2004) Chem. Biol , vol.11 , pp. 87
- Olano, C.¹ Wilkinson, B.² Sánchez, C.³ Moss, S.J.⁴ Sheridan, R.⁵ Math, V.⁶ Weston, A.J.⁷ Braña, A.F.⁸ Martin, C.J.⁹ Oliynyk, M.¹⁰ Méndez, C.¹¹ Leadlay, P.F.¹² Salas, J.A.¹³

185
- 0344099408
- C. Olano; B. Wilkinson; S. J. Moss; A. F. Braña; C. Méndez; P. F. Leadlay; J. A. Salas, Chem. Commun. 2003, 2780.
- (2003) Chem. Commun , pp. 2780
- Olano, C.¹ Wilkinson, B.² Moss, S.J.³ Braña, A.F.⁴ Méndez, C.⁵ Leadlay, P.F.⁶ Salas, J.A.⁷

186
- 33947303415
- S. W. Haynes; G. L. Challis, Curr. Opin. Drug. Discovery Dev. 2007, 10, 203.
- (2007) Curr. Opin. Drug. Discovery Dev , vol.10 , pp. 203
- Haynes, S.W.¹ Challis, G.L.²

187
- 0037066791
- N. Gaitatzis; B. Silakowski; B. Kunze; G. Nordsiek; H. Blocker; G. Höfle; R. Müller, J. Biol. Chem. 2002, 277, 13082.
- (2002) J. Biol. Chem , vol.277 , pp. 13082
- Gaitatzis, N.¹ Silakowski, B.² Kunze, B.³ Nordsiek, G.⁴ Blocker, H.⁵ Höfle, G.⁶ Müller, R.⁷

188
- 0346968190
- J. He; C. Hertweck, Chem. Biol. 2003, 10, 1225.
- (2003) Chem. Biol , vol.10 , pp. 1225
- He, J.¹ Hertweck, C.²

189
- 21044447751
- J. He; C. Hertweck, ChemBioChem 2005, 6, 908.
- (2005) ChemBioChem , vol.6 , pp. 908
- He, J.¹ Hertweck, C.²

190
- 0034141311
- B. Wilkinson; G. Foster; B. A. M. Rudd; N. L. Taylor; A. P. Blackaby; P. J. Sidebottom; D. J. Cooper; M. J. Dawson; A. D. Buss; S. Gaisser; I. U. Böhm; C. J. Rowe; J. Cortés; P. F. Leadlay; J. Staunton, Chem. Biol. 2000, 7, 111.
- (2000) Chem. Biol , vol.7 , pp. 111
- Wilkinson, B.¹ Foster, G.² Rudd, B.A.M.³ Taylor, N.L.⁴ Blackaby, A.P.⁵ Sidebottom, P.J.⁶ Cooper, D.J.⁷ Dawson, M.J.⁸ Buss, A.D.⁹ Gaisser, S.¹⁰ Böhm, I.U.¹¹ Rowe, C.J.¹² Cortés, J.¹³ Leadlay, P.F.¹⁴ Staunton, J.¹⁵

191
- 3042594469
- C. Olano; S. J. Moss; A. F. Braña; R. M. Sheridan; V. Math; A. J. Weston; C. Méndez; P. F. Leadlay; B. Wilkinson; J. A. Salas, Mol. Microbiol. 2004, 52, 1745.
- (2004) Mol. Microbiol , vol.52 , pp. 1745
- Olano, C.¹ Moss, S.J.² Braña, A.F.³ Sheridan, R.M.⁴ Math, V.⁵ Weston, A.J.⁶ Méndez, C.⁷ Leadlay, P.F.⁸ Wilkinson, B.⁹ Salas, J.A.¹⁰

192
- 30544434619
- K. J. Weissman; P. F. Leadlay, Nat. Rev. Microbiol. 2005, 3, 925.
- (2005) Nat. Rev. Microbiol , vol.3 , pp. 925
- Weissman, K.J.¹ Leadlay, P.F.²

193
- 34948842023
- A. Kirschning; F. Taft; T. Knobloch, Org. Biomol. Chem. 2007, 5, 3245.
- (2007) Org. Biomol. Chem , vol.5 , pp. 3245
- Kirschning, A.¹ Taft, F.² Knobloch, T.³

194
- 37549071045
- M.-Q. Zhang; B. Wilkinson, Curr. Opin. Biotechnol. 2007, 18, 478.
- (2007) Curr. Opin. Biotechnol , vol.18 , pp. 478
- Zhang, M.-Q.¹ Wilkinson, B.²

195
- 34250704344
- H. G. Menzelles; C. D. Reeves, Curr. Opin. Microbiol. 2007, 10, 238.
- (2007) Curr. Opin. Microbiol , vol.10 , pp. 238
- Menzelles, H.G.¹ Reeves, C.D.²

196
- 27844461167
- S. C. Wenzel; R. Müller, Curr. Opin. Biotechnol. 2005, 16, 594.
- (2005) Curr. Opin. Biotechnol , vol.16 , pp. 594
- Wenzel, S.C.¹ Müller, R.²

197
- 27944487132
- G. Schneider, Curr. Opin. Struct. Biol. 2005, 15, 629.
- (2005) Curr. Opin. Struct. Biol , vol.15 , pp. 629
- Schneider, G.¹

198
- 0345839252
- C. T. Walsh, Nat. Rev. Microbiol. 2003, 1, 65.
- (2003) Nat. Rev. Microbiol , vol.1 , pp. 65
- Walsh, C.T.¹

199
- 0027908014
- R. McDaniel; S. Ebert-Khosla; D. A. Hopwood; C. Khosla, Science 1993, 262, 1546.
- (1993) Science , vol.262 , pp. 1546
- McDaniel, R.¹ Ebert-khosla, S.² Hopwood, D.A.³ Khosla, C.⁴

200
- 0032921036
- R. Ziermann; M. C. Batlach, Biotechniques 1999, 26, 106.
- (1999) Biotechniques , vol.26 , pp. 106
- Ziermann, R.¹ Batlach, M.C.²

201
- 0033180108
- B. J. Rawlings, Nat. Prod. Rep. 1999, 16, 425.
- (1999) Nat. Prod. Rep , vol.16 , pp. 425
- Rawlings, B.J.¹

202
- 42549165756
- H. Zhang; Y. Wang; B. A. Pfeiffer, Mol. Pharmacol. 2008, 5, 212.
- (2008) Mol. Pharmacol , vol.5 , pp. 212
- Zhang, H.¹ Wang, Y.² Pfeiffer, B.A.³

203
- 0035793858
- B. A. Pfeifer; S. J. Admiraal; H. Gramajo; D. E. Cane; C. Khosla, Science 2001, 291, 1790.
- (2001) Science , vol.291 , pp. 1790
- Pfeifer, B.A.¹ Admiraal, S.J.² Gramajo, H.³ Cane, D.E.⁴ Khosla, C.⁵

204
- 0033574768
- R. S. Gokhale; S. Y. Tsuji; D. E. Cane; C. Khosla, Science 1999, 284, 482.
- (1999) Science , vol.284 , pp. 482
- Gokhale, R.S.¹ Tsuji, S.Y.² Cane, D.E.³ Khosla, C.⁴

205
- 0032738419
- Q. Xue; G. Ashley; C. R. Hutchinson; D. V. Santi, Proc. Natl. Acad. Sci. U.S.A. 1999, 96, 11740.
- (1999) Proc. Natl. Acad. Sci. U.S.A , vol.96 , pp. 11740
- Xue, Q.¹ Ashley, G.² Hutchinson, C.R.³ Santi, D.V.⁴

206
- 84906293973
- E. S. Sattely; M. A. Fischbach; C. T. Walsh, Nat. Prod. Rep. 2008, 25, 257.
- (2008) Nat. Prod. Rep , vol.25 , pp. 257
- Sattely, E.S.¹ Fischbach, M.A.² Walsh, C.T.³

207
- 34249661567
- S. Mutak, J. Antibiot. 2007, 60, 85.
- (2007) J. Antibiot , vol.60 , pp. 85
- Mutak, S.¹

208
- 33644921212
- S. Pal, Tetrahedron 2006, 62, 3171.
- (2006) Tetrahedron , vol.62 , pp. 3171
- Pal, S.¹

209
- 0026024283
- E. W. Hafner; B. W. Holley; K. S. Holdom; S. E. Lee; R. G. Wax; D. Beck; H. A. I. McArthur; W. C. Wernau, J. Antbiot. 1991, 44, 349.
- (1991) J. Antbiot , vol.44 , pp. 349
- Hafner, E.W.¹ Holley, B.W.² Holdom, K.S.³ Lee, S.E.⁴ Wax, R.G.⁵ Beck, D.⁶ McArthur, H.A.I.⁷ Wernau, W.C.⁸

210
- 0025981514
- C. J. Dutton; S. P. Gibson; A. C. Goudie; K. S. Holdom; M. S. Pacey; J. C. Ruddock; J. D. Bu'Lock; M. K. Richards, J. Antibiot. 1991, 44, 357.
- (1991) J. Antibiot , vol.44 , pp. 357
- Dutton, C.J.¹ Gibson, S.P.² Goudie, A.C.³ Holdom, K.S.⁴ Pacey, M.S.⁵ Ruddock, J.C.⁶ Bu'Lock, J.D.⁷ Richards, M.K.⁸

211
- 0032498205
- A. F. A. Marsden; B. Wilkinson; J. Cortés; N. J. Dunster; J. Staunton; P. F. Leadlay, Science 1998, 279, 199.
- (1998) Science , vol.279 , pp. 199
- Marsden, A.F.A.¹ Wilkinson, B.² Cortés, J.³ Dunster, N.J.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

212
- 0033578297
- H. Ikeda; T. Nonomiya; M. Usami; T. Ohta; S. Omura, Proc. Natl. Acad. Sci. U.S.A. 1999, 17, 9509.
- (1999) Proc. Natl. Acad. Sci. U.S.A , vol.17 , pp. 9509
- Ikeda, H.¹ Nonomiya, T.² Usami, M.³ Ohta, T.⁴ Omura, S.⁵

213
- 0013033285
- M. S. Pacey; J. P. Dirlam; R. W. Geldart; P. F. Leadlay; H. A. I. McArthur; E. L. McCormick; R. A. Monday; T. N. O'Connell; J. Staunton; T. J. Winchester, J. Antibiot. 1998, 51, 1029.
- (1998) J. Antibiot , vol.51 , pp. 1029
- Pacey, M.S.¹ Dirlam, J.P.² Geldart, R.W.³ Leadlay, P.F.⁴ McArthur, H.A.I.⁵ McCormick, E.L.⁶ Monday, R.A.⁷ O'Connell, T.N.⁸ Staunton, J.⁹ Winchester, T.J.¹⁰

214
- 0033017326
- I. C. Parsons; J. R. Everett; M. S. Pacey; J. C. Ruddock; A. G. Swanson; C. M. Thompson, J. Antibiot. 1999, 52, 190.
- (1999) J. Antibiot , vol.52 , pp. 190
- Parsons, I.C.¹ Everett, J.R.² Pacey, M.S.³ Ruddock, J.C.⁴ Swanson, A.G.⁵ Thompson, C.M.⁶

215
- 0032861758
- M. S. Brown; J. P. Dirlam; H. A. I. McArtur; E. L. McCormick; B. K. Morse; P. A. Murphy; T. N. O'Connell; M. Pacey; D. M. Rescek; J. Ruddock; R. G. Wax, J. Antibiot. 1999, 52, 742.
- (1999) J. Antibiot , vol.52 , pp. 742
- Brown, M.S.¹ Dirlam, J.P.² McArtur, H.A.I.³ McCormick, E.L.⁴ Morse, B.K.⁵ Murphy, P.A.⁶ O'Connell, T.N.⁷ Pacey, M.⁸ Rescek, D.M.⁹ Ruddock, J.¹⁰ Wax, R.G.¹¹

216
- 0030875774
- J. R. Jacobsen; C. R. Hutchinson; D. E. Cane; C. Khosla, Science 1997, 277, 367.
- (1997) Science , vol.277 , pp. 367
- Jacobsen, J.R.¹ Hutchinson, C.R.² Cane, D.E.³ Khosla, C.⁴

217
- 0035951074
- C. D. Reeves; S. Murli; G. W. Ashley; M. Piagentini; C. R. Hutchinson; R. McDaniel, Biochemistry 2001, 40, 15464.
- (2001) Biochemistry , vol.40 , pp. 15464
- Reeves, C.D.¹ Murli, S.² Ashley, G.W.³ Piagentini, M.⁴ Hutchinson, C.R.⁵ McDaniel, R.⁶

218
- 0037094002
- Y. Kato; L. Bai; Q. Xue; W. P. Revill; T.-W. Yu; H. G. Floss, J. Am. Chem. Soc. 2002, 124, 5268.
- (2002) J. Am. Chem. Soc , vol.124 , pp. 5268
- Kato, Y.¹ Bai, L.² Xue, Q.³ Revill, W.P.⁴ Yu, T.-W.⁵ Floss, H.G.⁶

219
- 0037062404
- T.-W. Yu; L. Bai; D. Clade; D. Hoffman; S. Toelzer; K. Q. Trinh; J. Xu; S. J. Moss; E. Leistner; H. G. Floss, Proc. Natl. Acad. Sci. U.S.A. 2002, 99, 7968.
- (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 7968
- Yu, T.-W.¹ Bai, L.² Clade, D.³ Hoffman, D.⁴ Toelzer, S.⁵ Trinh, K.Q.⁶ Xu, J.⁷ Moss, S.J.⁸ Leistner, E.⁹ Floss, H.G.¹⁰

220
- 0034643859
- K. Wu; L. Chung; W. P. Revill; L. Katz; C. D. Reeves, Gene 2000, 251, 81.
- (2000) Gene , vol.251 , pp. 81
- Wu, K.¹ Chung, L.² Revill, W.P.³ Katz, L.⁴ Reeves, C.D.⁵

221
- 33750730955
- S. C. Wenzel; R. M. Williamson; C. Grunanger; J. Xu; K. Gerth; R. A. Martinez; S. J. Moss; B. J. Carroll; S. Grond; C. J. Unkefen; R. Müller; H. G. Floss, J. Am. Chem. Soc. 2006, 128, 14325.
- (2006) J. Am. Chem. Soc , vol.128 , pp. 14325
- Wenzel, S.C.¹ Williamson, R.M.² Grunanger, C.³ Xu, J.⁴ Gerth, K.⁵ Martinez, R.A.⁶ Moss, S.J.⁷ Carroll, B.J.⁸ Grond, S.⁹ Unkefen, C.J.¹⁰ Müller, R.¹¹ Floss, H.G.¹²

222
- 33749249749
- Y. A. Chan; M. P. Boyne; A. M. Podevels; A. K. Klimowicz; J. Handelsman; N. L. Kelleher; M. G. Thomas, Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 14349.
- (2006) Proc. Natl. Acad. Sci. U.S.A , vol.103 , pp. 14349
- Chan, Y.A.¹ Boyne, M.P.² Podevels, A.M.³ Klimowicz, A.K.⁴ Handelsman, J.⁵ Kelleher, N.L.⁶ Thomas, M.G.⁷

223
- 4544238933
- P. A. Lowden; G. A. Böhm; S. Metcalfe; J. Staunton; P. F. Leadlay, ChemBioChem 2004, 5, 535.
- (2004) ChemBioChem , vol.5 , pp. 535
- Lowden, P.A.¹ Böhm, G.A.² Metcalfe, S.³ Staunton, J.⁴ Leadlay, P.F.⁵

224
- 33750505007
- R. J. M. Goss; S. E. Lanceron; N. J. Wise; S. J. Moss, Org. Biomol. Chem. 2006, 4, 4071.
- (2006) Org. Biomol. Chem , vol.4 , pp. 4071
- Goss, R.J.M.¹ Lanceron, S.E.² Wise, N.J.³ Moss, S.J.⁴

225
- 0141854979
- E. I. Graziani; F. V. Ritacio; M. Y. Summers; T. M. Zabriskie; K. Yu; V. S. Bernan; M. Greenstain; G. T. Carter, Org. Lett. 2003, 5, 2385.
- (2003) Org. Lett , vol.5 , pp. 2385
- Graziani, E.I.¹ Ritacio, F.V.² Summers, M.Y.³ Zabriskie, T.M.⁴ Yu, K.⁵ Bernan, V.S.⁶ Greenstain, M.⁷ Carter, G.T.⁸

226
- 17444433008
- F. V. Titacco; E. I. Graziani; M. Y. Summers; T. M. Zabriskie; K. Yu; V. S. Bernan; G. T. Carter; M. Greenstain, Appl. Environ. Microbiol. 2005, 71, 1971.
- (2005) Appl. Environ. Microbiol , vol.71 , pp. 1971
- Titacco, F.V.¹ Graziani, E.I.² Summers, M.Y.³ Zabriskie, T.M.⁴ Yu, K.⁵ Bernan, V.S.⁶ Carter, G.T.⁷ Greenstain, M.⁸

227
- 0343371621
- C. J. Rowe; I. U. Böhm; I. P. Thomas; B. Wilkinson; B. A. M. Rudd; G. Foster; A. P. Blackaby; P. J. Sidebottom; Y. Roddis; A. D. Buss; J. Staunton; P. F. Leadlay, Chem. Biol. 2001, 8, 475.
- (2001) Chem. Biol , vol.8 , pp. 475
- Rowe, C.J.¹ Böhm, I.U.² Thomas, I.P.³ Wilkinson, B.⁴ Rudd, B.A.M.⁵ Foster, G.⁶ Blackaby, A.P.⁷ Sidebottom, P.J.⁸ Roddis, Y.⁹ Buss, A.D.¹⁰ Staunton, J.¹¹ Leadlay, P.F.¹²

228
- 0035909913
- S.-C. Tsai; L. J. W. Miercke; J. Krudinksi; R. Gokhale; J. C.-H. Chen; P. G. Foster; D. E. Cane; C. Khosla; R. M. Stroud, Proc. Natl. Acad. Sci. U.S.A. 2001, 98, 14808.
- (2001) Proc. Natl. Acad. Sci. U.S.A , vol.98 , pp. 14808
- Tsai, S.-C.¹ Miercke, L.J.W.² Krudinksi, J.³ Gokhale, R.⁴ Chen, J.C.-H.⁵ Foster, P.G.⁶ Cane, D.E.⁷ Khosla, C.⁸ Stroud, R.M.⁹

229
- 42449119258
- F. Pankewitz; M. Hilker, Biol. Rev. 2008, 83, 209.
- (2008) Biol. Rev , vol.83 , pp. 209
- Pankewitz, F.¹ Hilker, M.²

230
- 34247465977
- L. Fieseler; U. Hentschel; L. Grozdanov; A. Schirmer; G. P. Wen; M. Platzer; S. Hrvatin; D. Butzke; K. Zimmerman; J. Piel, Appl. Environ. Microbiol. 2007, 73, 2144.
- (2007) Appl. Environ. Microbiol , vol.73 , pp. 2144
- Fieseler, L.¹ Hentschel, U.² Grozdanov, L.³ Schirmer, A.⁴ Wen, G.P.⁵ Platzer, M.⁶ Hrvatin, S.⁷ Butzke, D.⁸ Zimmerman, K.⁹ Piel, J.¹⁰

231
- 85047689741
- J. Piel, Curr. Med. Chem. 2006, 13, 39.
- (2006) Curr. Med. Chem , vol.13 , pp. 39
- Piel, J.¹

232
- 33846294808
- L. P. Partida-Martinez; C. Hertweck, ChemBioChem 2007, 8, 41.
- (2007) ChemBioChem , vol.8 , pp. 41
- Partida-martinez, L.P.¹ Hertweck, C.²

233
- 9244230571
- J. Piel; D. Hui; G. Wen; D. Butzke; M. Platzer; N. Fusetani; S. Matsunaga, Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 16222.
- (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 16222
- Piel, J.¹ Hui, D.² Wen, G.³ Butzke, D.⁴ Platzer, M.⁵ Fusetani, N.⁶ Matsunaga, S.⁷

234
- 0034141305
- I. Molnár; T. Schupp; M. Ono; R. E. Zirckle; M. Milnamow; B. Nowak-Thompson; N. Engel; C. Toupet; A. Stratmann; D. D. Cyr; J. Gorlach; J. M. Mayo; A. Hu; S. Goff; J. Schmid; J. M. Ligon, Chem. Biol. 2000, 7, 97.
- (2000) Chem. Biol , vol.7 , pp. 97
- Molnár, I.¹ Schupp, T.² Ono, M.³ Zirckle, R.E.⁴ Milnamow, M.⁵ Nowak-thompson, B.⁶ Engel, N.⁷ Toupet, C.⁸ Stratmann, A.⁹ Cyr, D.D.¹⁰ Gorlach, J.¹¹ Mayo, J.M.¹² Hu, A.¹³ Goff, S.¹⁴ Schmid, J.¹⁵ Ligon, J.M.¹⁶

235
- 0034723333
- L. Tang; S. Shah; R. Zimmerman; R. Goldman; L. Katz; B. Julien, Science 2000, 287, 640.
- (2000) Science , vol.287 , pp. 640
- Tang, L.¹ Shah, S.² Zimmerman, R.³ Goldman, R.⁴ Katz, L.⁵ Julien, B.⁶

236
- 34848911303
- S. Donadio; P. Mociardini; M. Sosio, Nat. Prod. Rep. 2007, 24, 1073.
- (2007) Nat. Prod. Rep , vol.24 , pp. 1073
- Donadio, S.¹ Mociardini, P.² Sosio, M.³

237
- 33748631825
- M. A. Fischbach; C. T. Walsh, Chem. Rev. 2006, 106, 3468.
- (2006) Chem. Rev , vol.106 , pp. 3468
- Fischbach, M.A.¹ Walsh, C.T.²

238
- 84906286139
- Y.-Q. Cheng; G.-L. Tang; B. Shen, J. Bacteriol. 2002, 184, 7103.
- (2002) J. Bacteriol , vol.184 , pp. 7103
- Cheng, Y.-Q.¹ Tang, G.-L.² Shen, B.³

239
- 0037452928
- Y.-Q. Cheng; G.-L. Tang; B. Shen, Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 3149.
- (2003) Proc. Natl. Acad. Sci. U.S.A , vol.100 , pp. 3149
- Cheng, Y.-Q.¹ Tang, G.-L.² Shen, B.³

240
- 58149095417
- Y. A. Chan; A. M. Podevels; B. M. Kevany; M. G. Thomas, Nat. Prod. Rep. 2009, 26, 90.
- (2009) Nat. Prod. Rep , vol.26 , pp. 90
- Chan, Y.A.¹ Podevels, A.M.² Kevany, B.M.³ Thomas, M.G.⁴

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