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ChemBioChem

Volumn 7, Issue 9, 2006, Pages 1334-1342

Single amino acid substitutions alter the efficiency of docking in modular polyketide biosynthesis

(1) Weissman, Kira J a

a UNIVERSITY OF CAMBRIDGE (United Kingdom)

Author keywords

Biosynthesis; Docking domains; Erythromycin; Polyketides; Protein protein recognition

Indexed keywords

ACYL CARRIER PROTEIN; ACYLTRANSFERASE; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; ERYTHROMYCIN; IMMUNOSUPPRESSIVE AGENT; LACTONE; MACROLIDE; OLEANDOMYCIN; PIKROMYCIN; POLYKETIDE; POLYKETIDE SYNTHASE;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIOPHAGE; BIOSYNTHESIS; ESCHERICHIA COLI; NONHUMAN; PLASMID; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STREPTOMYCES;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ESCHERICHIA COLI; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LACTONES; MACROLIDES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; POLYKETIDE SYNTHASES; PROTEIN ENGINEERING; PROTEIN STRUCTURE, TERTIARY; SACCHAROPOLYSPORA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFORMATION, GENETIC;

EID: 33748577348 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.200600185 Document Type: Article

Times cited : (20)

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