The pipecolate-incorporating enzyme for the biosynthesis of the immunosuppressant rapamycin - Nucleotide sequence analysis, disruption and heterologous expression of rapP from Streptomyces hygroscopicus

European Journal of Biochemistry

Volumn 247, Issue 2, 1997, Pages 526-534

  König, Ariane ^a   Schwecke, Torsten ^a   Molnár, István ^a   Böhm, Günter A ^a   Lowden, Philip A S ^a   Staunton, James ^a   Leadlay, Peter F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Non ribosomal peptide synthetase; Pipecolate incorporating enzyme; Polyketide biosynthesis; Rapamycin; Streptomyces hygroscopicus

Indexed keywords

PEPTIDE SYNTHASE; PIPECOLIC ACID; RAPAMYCIN;

AMINO ACID SEQUENCE; ARTICLE; BACTERIOPHAGE; BIOSYNTHESIS; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; GENE EXPRESSION; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STREPTOMYCES COELICOLOR; STREPTOMYCES HYGROSCOPICUS;

ESCHERICHIA COLI; STREPTOMYCES COELICOLOR; STREPTOMYCES HYGROSCOPICUS;

EID: 0030872295     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00526.x     Document Type: Article

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