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ChemBioChem

Volumn 5, Issue 4, 2004, Pages 535-538

New rapamycin derivatives by precursor-directed biosynthesis

(5) Lowden, Philip A S a,b Böhm, Günter A c Metcalfe, Su d Staunton, James c Leadlay, Peter F c

a UNIVERSITY OF EXETER (United Kingdom)

b UNIVERSITY OF LONDON (United Kingdom)

c UNIVERSITY OF CAMBRIDGE (United Kingdom)

d UNIVERSITY OF CAMBRIDGE (United Kingdom)

Author keywords

Biosynthesis; Loading module; Polyketides; Rapamycin

Indexed keywords

ASCOMYCIN; RAPAMYCIN; TACROLIMUS; CARBOXYLIC ACID; MULTIENZYME COMPLEX; PRODRUG; SOLVENT;

ARTICLE; DRUG SYNTHESIS; ENZYME ACTIVITY; GENETIC CODE; HYDROXYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRECURSOR; PRIORITY JOURNAL; CHEMICAL STRUCTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERISM; METABOLISM; STREPTOMYCES;

CARBOXYLIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ISOMERISM; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; PRODRUGS; SIROLIMUS; SOLVENTS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STREPTOMYCES;

EID: 4544238933 PISSN: 14394227 EISSN: None Source Type: Journal
DOI: 10.1002/cbic.200300758 Document Type: Article

Times cited : (46)

References (28)

1
- 0005937477
- A. B. Smith, S. M. Condon, J. A. McCauley, Acc. Chem. Res. 1998, 31, 31.
- (1998) Acc. Chem. Res. , vol.31 , pp. 31
- Smith, A.B.¹ Condon, S.M.² McCauley, J.A.³

2
- 15844391440
- a) F. J. Dumont, Q. X. Su, Life Sci. 1995, 58, 373;
- (1995) Life Sci. , vol.58 , pp. 373
- Dumont, F.J.¹ Su, Q.X.²

3
- 0034891425
- b) J. Mann, Nat. Prod. Rep. 2001, 18, 417.
- (2001) Nat. Prod. Rep. , vol.18 , pp. 417
- Mann, J.¹

4
- 0025973839
- N. L. Paiva, A. L. Demain, M. F. Roberts, J. Nat. Prod. 1991, 54, 167.
- (1991) J. Nat. Prod. , vol.54 , pp. 167
- Paiva, N.L.¹ Demain, A.L.² Roberts, M.F.³

5
- 0027845217
- N. L. Paiva, M. F. Roberts, A. L. Demain, J. Ind. Microbiol. 1993, 12, 423.
- (1993) J. Ind. Microbiol. , vol.12 , pp. 423
- Paiva, N.L.¹ Roberts, M.F.² Demain, A.L.³

6
- 0029098323
- a) T. Schwecke, J. F. Aparicio, I. Molnár, A. König, L. E. Khaw, S. F. Haydock, M. Oliynyk, P. Caffrey, J. Cortes, J. B. Lester, G. A. Böhm, J. Staunton, P. F. Leadlay, Proc. Natl. Acad. Sci. USA 1995, 92, 7839;
- (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7839
- Schwecke, T.¹ Aparicio, J.F.² Molnár, I.³ König, A.⁴ Khaw, L.E.⁵ Haydock, S.F.⁶ Oliynyk, M.⁷ Caffrey, P.⁸ Cortes, J.⁹ Lester, J.B.¹⁰ Böhm, G.A.¹¹ Staunton, J.¹² Leadlay, P.F.¹³

7
- 0029883934
- b) I. Molnár, J. F. Aparicio, S. F. Haydock, L. E. Khaw, T. Schwecke, A. König, J. Staunton, P. F. Leadlay, Gene 1996, 169, 1;
- (1996) Gene , vol.169 , pp. 1
- Molnár, I.¹ Aparicio, J.F.² Haydock, S.F.³ Khaw, L.E.⁴ Schwecke, T.⁵ König, A.⁶ Staunton, J.⁷ Leadlay, P.F.⁸

8
- 0029872079
- c) J. F. Aparicio, I. Molnár, T. Schwecke, A. König, S. F. Haydock, L. E. Khaw, J. Staunton, P. F. Leadlay, Gene 1996, 169, 9.
- (1996) Gene , vol.169 , pp. 9
- Aparicio, J.F.¹ Molnár, I.² Schwecke, T.³ König, A.⁴ Haydock, S.F.⁵ Khaw, L.E.⁶ Staunton, J.⁷ Leadlay, P.F.⁸

9
- 0030872295
- A. König, T. Schwecke, I. Molnár, G. A. Böhm, P. A. S. Lowden, J. Staunton, P. F. Leadlay, Eur J. Biochem. 1997, 247, 526.
- (1997) Eur J. Biochem. , vol.247 , pp. 526
- König, A.¹ Schwecke, T.² Molnár, I.³ Böhm, G.A.⁴ Lowden, P.A.S.⁵ Staunton, J.⁶ Leadlay, P.F.⁷

10
- 0030266007
- a) M. Oliynyk, M. J. B. Brown, J. Cortes, J. Staunton, P. F. Leadlay, Chem. Biol. 1996, 3, 833;
- (1996) Chem. Biol. , vol.3 , pp. 833
- Oliynyk, M.¹ Brown, M.J.B.² Cortes, J.³ Staunton, J.⁴ Leadlay, P.F.⁵

11
- 0033515090
- b) R. McDaniel, A. Thamchaipenet, C. Gustafsson, H. Fu, M. Betlach, G. Ashley, Proc. Natl. Acad. Sci. USA 1999, 96, 1846.
- (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1846
- McDaniel, R.¹ Thamchaipenet, A.² Gustafsson, C.³ Fu, H.⁴ Betlach, M.⁵ Ashley, G.⁶

12
- 0033215222
- a) A. Ranganathan, M. Timoney, M. Bycroft, J. Cortes, I. P. Thomas, B. Wilkinson, L. Kellenberger, U. Hanefeld, I. S. Galloway, J. Staunton, P. F. Leadlay, Chem. Biol. 1999, 6, 731;
- (1999) Chem. Biol. , vol.6 , pp. 731
- Ranganathan, A.¹ Timoney, M.² Bycroft, M.³ Cortes, J.⁴ Thomas, I.P.⁵ Wilkinson, B.⁶ Kellenberger, L.⁷ Hanefeld, U.⁸ Galloway, I.S.⁹ Staunton, J.¹⁰ Leadlay, P.F.¹¹

13
- 0343371621
- b) C. J. Rowe, I. U. Böhm, I. P.Thomas, B. Wilkinson, B. A. Rudd, G. Foster, A. P. Blackaby, P. J. Sidebottom, Y. Roddis, A. D. Buss, J. Staunton, P. F. Leadlay, Chem. Biol. 2001, 8, 475.
- (2001) Chem. Biol. , vol.8 , pp. 475
- Rowe, C.J.¹ Böhm, I.U.² Thomas, I.P.³ Wilkinson, B.⁴ Rudd, B.A.⁵ Foster, G.⁶ Blackaby, A.P.⁷ Sidebottom, P.J.⁸ Roddis, Y.⁹ Buss, A.D.¹⁰ Staunton, J.¹¹ Leadlay, P.F.¹²

14
- 0035027745
- L. Chung, L. Liu, S. Patel, J. R. Carney, C. D. Reeves, J. Antibiot. 2001, 54, 250.
- (2001) J. Antibiot. , vol.54 , pp. 250
- Chung, L.¹ Liu, L.² Patel, S.³ Carney, J.R.⁴ Reeves, C.D.⁵

15
- 0042530620
- P. A. S. Lowden, B. Wilkinson, G. A. Böhm, S. Handa, H. G. Floss, P. F. Leadlay, J. Staunton, Angew. Chem. 2001, 113, 799; Angew. Chem. Int. Ed. 2001, 40, 777.
- (2001) Angew. Chem. , vol.113 , pp. 799
- Lowden, P.A.S.¹ Wilkinson, B.² Böhm, G.A.³ Handa, S.⁴ Floss, H.G.⁵ Leadlay, P.F.⁶ Staunton, J.⁷

16
- 0035804386
- P. A. S. Lowden, B. Wilkinson, G. A. Böhm, S. Handa, H. G. Floss, P. F. Leadlay, J. Staunton, Angew. Chem. 2001, 113, 799; Angew. Chem. Int. Ed. 2001, 40, 777.
- (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 777

17
- 4544250356
- P. A. S. Lowden, G. A. Böhm, P. F. Leadlay, J. Staunton, Angew. Chem. 1996, 108, 3295; Angew. Chem. Int. Ed. Engl. 1996, 35, 2249.
- (1996) Angew. Chem. , vol.108 , pp. 3295
- Lowden, P.A.S.¹ Böhm, G.A.² Leadlay, P.F.³ Staunton, J.⁴

18
- 0030460449
- P. A. S. Lowden, G. A. Böhm, P. F. Leadlay, J. Staunton, Angew. Chem. 1996, 108, 3295; Angew. Chem. Int. Ed. Engl. 1996, 35, 2249.
- (1996) Angew. Chem. Int. Ed. Engl. , vol.35 , pp. 2249

19
- 0027618546
- R. Thiericke, J. Rohr, Nat. Prod. Rep. 1993, 10, 265.
- (1993) Nat. Prod. Rep. , vol.10 , pp. 265
- Thiericke, R.¹ Rohr, J.²

20
- 0036007875
- B. S. Moore, C. Hertweck, Nat. Prod. Rep. 2002, 19, 70.
- (2002) Nat. Prod. Rep. , vol.19 , pp. 70
- Moore, B.S.¹ Hertweck, C.²

21
- 0029111959
- a) H. Nishida, T. Sakakibara, F. Aoki, T. Saito, K. Ichikawa, T. Inagaki, Y. Kojima, Y. Yamauchi, L. H. Huang, M. A. Guadliana, T. Kaneko, N. Kojima, J. Antibiot. 1995, 48, 657;
- (1995) J. Antibiot. , vol.48 , pp. 657
- Nishida, H.¹ Sakakibara, T.² Aoki, F.³ Saito, T.⁴ Ichikawa, K.⁵ Inagaki, T.⁶ Kojima, Y.⁷ Yamauchi, Y.⁸ Huang, L.H.⁹ Guadliana, M.A.¹⁰ Kaneko, T.¹¹ Kojima, N.¹²

22
- 0141854979
- b) E. I. Graziani, F. V. Ritacco, M. Y. Summers, T. M. Zabriskie, K. Yu, V. S. Bernan, M. Greenstein, G. T. Carter, Org. Lett. 2003, 5, 2385.
- (2003) Org. Lett. , vol.5 , pp. 2385
- Graziani, E.I.¹ Ritacco, F.V.² Summers, M.Y.³ Zabriskie, T.M.⁴ Yu, K.⁵ Bernan, V.S.⁶ Greenstein, M.⁷ Carter, G.T.⁸

23
- 2642591970
- L. E. Khaw, G. A. Böhm, S. Metcalfe, J. Staunton, P. F. Leadlay, J. Bacteriol. 1998, 180, 809.
- (1998) J. Bacteriol. , vol.180 , pp. 809
- Khaw, L.E.¹ Böhm, G.A.² Metcalfe, S.³ Staunton, J.⁴ Leadlay, P.F.⁵

24
- 0025876348
- J. B. McAlpine, S. J. Swanson, M. Jackson, D. N. Whittern, J. Antibiot. 1991, 44, 688.
- (1991) J. Antibiot. , vol.44 , pp. 688
- McAlpine, J.B.¹ Swanson, S.J.² Jackson, M.³ Whittern, D.N.⁴

25
- 0026697506
- P. Hughes, J. Musser, M. Conklin, R. Russo, Tetrahedron Lett. 1992, 33, 4739.
- (1992) Tetrahedron Lett. , vol.33 , pp. 4739
- Hughes, P.¹ Musser, J.² Conklin, M.³ Russo, R.⁴

26
- 0030694253
- S. Metcalfe, C. E. Canman, J. Milner, R. E. Morris, S. Goldman, M. B. Kastan, Oncogens 1997, 15, 1635.
- (1997) Oncogens , vol.15 , pp. 1635
- Metcalfe, S.¹ Canman, C.E.² Milner, J.³ Morris, R.E.⁴ Goldman, S.⁵ Kastan, M.B.⁶

27
- 0032498205
- a) A. F. A. Marsden, B. Wilkinson, J. Cortes, N. J. Dunster, J. Staunton, P.F. Leadlay, Science 1998, 279, 199;
- (1998) Science , vol.279 , pp. 199
- Marsden, A.F.A.¹ Wilkinson, B.² Cortes, J.³ Dunster, N.J.⁴ Staunton, J.⁵ Leadlay, P.F.⁶

28
- 0013033285
- b) M. S. Pacey, J. P. Dirlam, R. W. Geldart, P. F. Leadlay, H. A. I. McArthur, E. L. McCormick, R. A. Monday, T. N. O'Connell, J. Staunton, T. J. Winchester, J. Antibiot. 1998, 51, 1029.
- (1998) J. Antibiot. , vol.51 , pp. 1029
- Pacey, M.S.¹ Dirlam, J.P.² Geldart, R.W.³ Leadlay, P.F.⁴ McArthur, H.A.I.⁵ McCormick, E.L.⁶ Monday, R.A.⁷ O'Connell, T.N.⁸ Staunton, J.⁹ Winchester, T.J.¹⁰

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