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Volumn 3, Issue 2, 1996, Pages 188-192

Evidence for a double-helical structure for modular polyketide synthases

Author keywords

[No Author keywords available]

Indexed keywords

DIMER; POLYKETIDE; SYNTHETASE;

EID: 0030065324     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb0296-188     Document Type: Article
Times cited : (118)

References (14)
  • 1
    • 0025081416 scopus 로고
    • An unusually large multifunctional polypeptide in the erythromydn-producing polyketide synthase of Saccharopolyspora erythraea
    • Cortés, J., Haydock, S.F., Roberts, G.A., Bevitt, D.J. & Leadlay, P.P. An unusually large multifunctional polypeptide in the erythromydn-producing polyketide synthase of Saccharopolyspora erythraea. Nature 348, 175-178 (1990).
    • (1990) Nature , vol.348 , pp. 175-178
    • Cortés, J.1    Haydock, S.F.2    Roberts, G.A.3    Bevitt, D.J.4    Leadlay, P.P.5
  • 2
    • 0026415106 scopus 로고
    • Modular organization of genes required for complex polyketide formation
    • Donadio, S., Staver, M.J., McAlpine, J.B., Swanson, S.J. & Katz, L. Modular organization of genes required for complex polyketide formation. Science 252, 675-679 (1991).
    • (1991) Science , vol.252 , pp. 675-679
    • Donadio, S.1    Staver, M.J.2    McAlpine, J.B.3    Swanson, S.J.4    Katz, L.5
  • 3
    • 0026667294 scopus 로고
    • Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase
    • MacNeil, D.J. et al. Complex organization of the Streptomyces avermitilis genes encoding the avermectin polyketide synthase. Gene 115, 119-125 (1992).
    • (1992) Gene , vol.115 , pp. 119-125
    • MacNeil, D.J.1
  • 4
    • 0028044628 scopus 로고
    • Characterization of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence
    • Swan, D.G., Rodriguez. A.M., Vilches, C., Méndez, C. & Salas, J.A. Characterization of a Streptomyces antibioticus gene encoding a type I polyketide synthase which has an unusual coding sequence. Mol. Gen. Genet. 242, 358-362 (1994).
    • (1994) Mol. Gen. Genet. , vol.242 , pp. 358-362
    • Swan, D.G.1    Rodriguez, A.M.2    Vilches, C.3    Méndez, C.4    Salas, J.A.5
  • 5
    • 0029098323 scopus 로고
    • The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin
    • Schwecke, T. et al. The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin. Proc. Natl. Acad. Sci. USA 92, 7839-7843 (1995)
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 7839-7843
    • Schwecke, T.1
  • 6
    • 0028131912 scopus 로고
    • Repeated polyketide synthase modules involved in the biosynthesis of a heptaene macrolide by Streptomyces sp. FR-008
    • Hu, Z.H. et al. Repeated polyketide synthase modules involved in the biosynthesis of a heptaene macrolide by Streptomyces sp. FR-008. Mol. Microbiol. 14, 163-172 (1994).
    • (1994) Mol. Microbiol. , vol.14 , pp. 163-172
    • Hu, Z.H.1
  • 7
    • 0025606149 scopus 로고
    • Molecular genetics of polyketide synthesis and its comparison to fatty acid biosynthesis
    • Hopwood, D.A. & Sherman, D. H. Molecular genetics of polyketide synthesis and its comparison to fatty acid biosynthesis. Annu. Rev. Genet. 24, 37-66 (1990).
    • (1990) Annu. Rev. Genet. , vol.24 , pp. 37-66
    • Hopwood, D.A.1    Sherman, D.H.2
  • 8
    • 0025936455 scopus 로고
    • The extraordinary enzymes involved in erythromycin biosynthesis
    • Staunton, J. The extraordinary enzymes involved in erythromycin biosynthesis. Ang. Chem. Int. Ed. Engl. 30, 1302-1306 (1991).
    • (1991) Ang. Chem. Int. Ed. Engl. , vol.30 , pp. 1302-1306
    • Staunton, J.1
  • 9
    • 0027382486 scopus 로고
    • Polyketide synthesis - Prospects for hybrid antibiotics
    • Katz, L. & Donadio, S. Polyketide synthesis - prospects for hybrid antibiotics. Anna. Rev. Microbiol. 47, 875-912 (1993).
    • (1993) Anna. Rev. Microbiol. , vol.47 , pp. 875-912
    • Katz, L.1    Donadio, S.2
  • 10
    • 0028811381 scopus 로고
    • Polyketide synthase gene manipulation: A structure-function approach in engineering novel antibiotics
    • Hutchinson, C. R. & Fujii, I. Polyketide synthase gene manipulation: a structure-function approach in engineering novel antibiotics. Annu. Rev. Microbiol. 49.201-238 (1995).
    • (1995) Annu. Rev. Microbiol. , vol.49 , pp. 201-238
    • Hutchinson, C.R.1    Fujii, I.2
  • 11
    • 0026511543 scopus 로고
    • 6-deoxyerythronolide B synthase-2 from Saccharopolyspora erythraea -cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme
    • Bevitt, D.J., Cortés, J., Haydock, S.F. & Leadlay, P.F. 6-deoxyerythronolide B synthase-2 from Saccharopolyspora erythraea -cloning of the structural gene, sequence analysis and inferred domain structure of the multifunctional enzyme. Eur. J. Biochem. 204, 39-49 (1992).
    • (1992) Eur. J. Biochem. , vol.204 , pp. 39-49
    • Bevitt, D.J.1    Cortés, J.2    Haydock, S.F.3    Leadlay, P.F.4
  • 12
    • 0024315871 scopus 로고
    • Fatty acid synthase - A proficient multifunctional enzyme
    • Wakil, S.J. Fatty acid synthase - a proficient multifunctional enzyme. Biochemistry 28,4523-4530(1989).
    • (1989) Biochemistry , vol.28 , pp. 4523-4530
    • Wakil, S.J.1
  • 13
    • 0027381395 scopus 로고
    • Construction, expression, and characterization of a mutated animal fatty acid synthase deficient in the dehydrase function
    • Joshi, A.K. & Smith, S. Construction, expression, and characterization of a mutated animal fatty acid synthase deficient in the dehydrase function. J. Biol. Chem. 268, 22508-22513 (1995).
    • (1995) J. Biol. Chem. , vol.268 , pp. 22508-22513
    • Joshi, A.K.1    Smith, S.2
  • 14
    • 0026697224 scopus 로고
    • Identification of DEBS-1, DEBS-2 and DEBS-3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea
    • Caffrey, P., Bevitt, D.J., Staunton, J. & Leadlay, P. F. Identification of DEBS-1, DEBS-2 and DEBS-3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea. FEBS Letters 304, 225-228 (1992).
    • (1992) FEBS Letters , vol.304 , pp. 225-228
    • Caffrey, P.1    Bevitt, D.J.2    Staunton, J.3    Leadlay, P.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.