Analysis of the tetronomycin gene cluster: Insights into the biosynthesis of a polyether tetronate antibiotic

ChemBioChem

Volumn 9, Issue 7, 2008, Pages 1136-1145

  Demydchuk, Yuliya ^a   Sun, Yuhui ^a   Hong, Hui ^a   Staunton, James ^a   Spencer, Jonathan B ^a   Leadlay, Peter F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antibiotics; Biosynthesis; Ionophores; Polyethers; Polyketides

Indexed keywords

ANTIBIOTIC AGENT; CHLOROTHRICIN; POLYETHER TETRONATE ANTIBIOTIC; POLYKETIDE SYNTHASE; TETRONASIN; TETRONOMYCIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; CARBON; CARRIER PROTEIN; ETHER DERIVATIVE; FURAN DERIVATIVE; TETRONIC ACID;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CONTROLLED STUDY; GENE CLUSTER; GENE DELETION; GENE DISRUPTION; GENE LOCUS; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PREDICTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; AMINO ACID SEQUENCE; BIOSYNTHESIS; CHEMISTRY; DNA SEQUENCE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; MUTATION; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; STREPTOMYCES;

STREPTOMYCES SP.;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; CARBON; CARRIER PROTEINS; CLONING, MOLECULAR; ETHERS; FURANS; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTATION; OPEN READING FRAMES; POLYKETIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; STREPTOMYCES;

EID: 46649112563     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200700715     Document Type: Article

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