Solution structure and proposed domain-domain recognition interface of an acyl carrier protein domain from a modular polyketide synthase

Protein Science

Volumn 16, Issue 10, 2007, Pages 2093-2107

  Alekseyev, Viktor Y ^a   Liu, Corey W ^b   Cane, David E ^c   Puglisi, Joseph D ^b   Khosla, Chaitan ^a,d  

^a STANFORD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

^d Stanford University   (United States)

Author keywords

Acyl carrier protein; Electrostatic; Homology modeling; Mutagenesis; NMR; Polyketide; Protein interaction; Structure

Indexed keywords

6 DEOXYERYTHRONOLIDE B SYNTHASE; ACYL CARRIER PROTEIN; ERYTHRONOLIDE B; NATURAL PRODUCT; POLYKETIDE; POLYKETIDE SYNTHASE; POLYPEPTIDE; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; COVALENT BOND; ELECTRICITY; MOLECULAR RECOGNITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSICOCHEMICAL MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; RESIDUE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; STRUCTURAL HOMOLOGY;

ACYL CARRIER PROTEIN; AMINO ACID SEQUENCE; BINDING SITES; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROSTATICS; LACTONES; MIXED FUNCTION OXYGENASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHYLOGENY; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SOLUTIONS; STRUCTURAL HOMOLOGY, PROTEIN;

EID: 34547933299     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.073011407     Document Type: Article

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