-
1
-
-
0036499123
-
Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States: Results from the TRUST Surveillance Program, 1999-2000
-
Thornsberry, C. et al. Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States: results from the TRUST Surveillance Program, 1999-2000. Clin. Infect. Dis. 34, S4-S16 (2002).
-
(2002)
Clin. Infect. Dis.
, vol.34
, pp. S4-S16
-
-
Thornsberry, C.1
-
2
-
-
0035823272
-
Humans as the world's greatest evolutionary force
-
Palumbi, S. R. Humans as the world's greatest evolutionary force. Science 293, 1786-1790 (2001).
-
(2001)
Science
, vol.293
, pp. 1786-1790
-
-
Palumbi, S.R.1
-
3
-
-
0042908666
-
-
ASM Press, Washington DC, USA
-
Walsh, C. T. Antibiotics: Actions, Origins, Resistance. (ASM Press, Washington DC, USA, 2003).
-
(2003)
Antibiotics: Actions, Origins, Resistance
-
-
Walsh, C.T.1
-
4
-
-
0036834373
-
The future challenges facing the development of new antimicrobial drugs
-
Coates, A., Hu, Y, Bax, R. & Page, C. The future challenges facing the development of new antimicrobial drugs. Nature Rev. Drug Discov. 1, 895-910 (2002).
-
(2002)
Nature Rev. Drug Discov.
, vol.1
, pp. 895-910
-
-
Coates, A.1
Hu, Y.2
Bax, R.3
Page, C.4
-
5
-
-
0033790259
-
Development of daptomycin for gram-positive infections
-
Tally, F. P. & DeBruin, M. F. Development of daptomycin for gram-positive infections. J. Antimicrob. Chemother. 46, 523-526 (2000).
-
(2000)
J. Antimicrob. Chemother.
, vol.46
, pp. 523-526
-
-
Tally, F.P.1
Debruin, M.F.2
-
6
-
-
0035079979
-
Expression and isolation of small molecules from soil DNA libraries
-
MacNeil, I. A. et al. Expression and isolation of small molecules from soil DNA libraries. J. Mol. Microbiol. Biotechnol. 3, 301-308 (2001).
-
(2001)
J. Mol. Microbiol. Biotechnol.
, vol.3
, pp. 301-308
-
-
Macneil, I.A.1
-
7
-
-
4244059507
-
Harnessing the biosynthetic potential of modular polyketide synthases
-
Khosla, C. Harnessing the biosynthetic potential of modular polyketide synthases. Chem. Rev. 97, 2577-2590 (1997).
-
(1997)
Chem. Rev.
, vol.97
, pp. 2577-2590
-
-
Khosla, C.1
-
8
-
-
0032475992
-
Harnessing the biosynthetic code; combinations, permutations, and mutations
-
Cane, D. E., Walsh, C. T. & Khosla, C. Harnessing the biosynthetic code; combinations, permutations, and mutations. Science 282, 63-68 (1998).
-
(1998)
Science
, vol.282
, pp. 63-68
-
-
Cane, D.E.1
Walsh, C.T.2
Khosla, C.3
-
9
-
-
0029942660
-
Cotrimoxazole, rationale for re-examining its indications for use
-
Howe, R. A. & Spencer, R. C. Cotrimoxazole, rationale for re-examining its indications for use. Drug Saf. 14, 213-218 (1996).
-
(1996)
Drug Saf
, vol.14
, pp. 213-218
-
-
Howe, R.A.1
Spencer, R.C.2
-
11
-
-
0031105464
-
DNA Gyrase as a drug target
-
Maxwell, A. DNA Gyrase as a drug target. Trends Microbiol 5, 102-109 (1997).
-
(1997)
Trends Microbiol
, vol.5
, pp. 102-109
-
-
Maxwell, A.1
-
12
-
-
0035910436
-
Diversity-based organic synthesis in the era of genomics and proteomics
-
Arya, P D., Chou, T. H. & Baek, M. G. Diversity-based organic synthesis in the era of genomics and proteomics. Angew. Chem. Int. Ed. 40, 339-346 (2001).
-
(2001)
Angew. Chem. Int. Ed.
, vol.40
, pp. 339-346
-
-
Arya, P.D.1
Chou, T.H.2
Baek, M.G.3
-
13
-
-
0036008841
-
Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age
-
Arya, P D., Joseph, R. & Chou, D. T. Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age. Chem. Biol. 9, 145-146 (2002).
-
(2002)
Chem. Biol.
, vol.9
, pp. 145-146
-
-
Arya, P.D.1
Joseph, R.2
Chou, D.T.3
-
14
-
-
0034678033
-
Target-oriented and diversity-oriented organic synthesis in drug discovery
-
Schreiber, S. L. Target-oriented and diversity-oriented organic synthesis in drug discovery. Science 287, 1964-1969 (2000).
-
(2000)
Science
, vol.287
, pp. 1964-1969
-
-
Schreiber, S.L.1
-
15
-
-
0033576601
-
The design of leadlike combinatorial libraries
-
Teague, S., Leason, D., Oprea, P. D. & Davis, T. The design of leadlike combinatorial libraries Angew. Chem. Int. Ed. 38, 3743-3748 (1999).
-
(1999)
Angew. Chem. Int. Ed
, vol.38
, pp. 3743-3748
-
-
Teague, S.1
Leason, D.2
Oprea, P.D.3
Davis, T.4
-
16
-
-
0033515090
-
Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of "unnatural" natural products
-
McDaniel, R. A. et al. Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of "unnatural" natural products. Proc. Natl Acad. Sci. USA 96, 1846-1851 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 1846-1851
-
-
McDaniel, R.A.1
-
17
-
-
0036523418
-
Combinatorial biosynthesis of antibiotics: Challenges and opportunities
-
Walsh, C. T. Combinatorial biosynthesis of antibiotics: challenges and opportunities. Chem. Biochem. 3, 124-134 (2002).
-
(2002)
Chem. Biochem.
, vol.3
, pp. 124-134
-
-
Walsh, C.T.1
-
18
-
-
0034699519
-
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
-
Carter, A. P. et al. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 407, 340-348 (2000).
-
(2000)
Nature
, vol.407
, pp. 340-348
-
-
Carter, A.P.1
-
19
-
-
0036342198
-
The structures of four macrolide antibiotics bound to the large ribosomal subunit
-
Hansen, J. L. et al. The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol. Cell 10, 117-128 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 117-128
-
-
Hansen, J.L.1
-
20
-
-
17744377418
-
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine, and IF3
-
Pioletti, M. et al. Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine, and IF3. EMBO J. 20, 1829-1839 (2001).
-
(2001)
EMBO J
, vol.20
, pp. 1829-1839
-
-
Pioletti, M.1
-
21
-
-
0035950132
-
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
-
Schlunzen, F. R. et al. Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature 413, 814-821 (2001).
-
(2001)
Nature
, vol.413
, pp. 814-821
-
-
Schlunzen, F.R.1
-
22
-
-
0035166979
-
The comprehensive microbial resource
-
Peterson, T. D. et al. The comprehensive microbial resource. Nucl. Acids Res. 29, 123-125 (2001).
-
(2001)
Nucl. Acids Res.
, vol.29
, pp. 123-125
-
-
Peterson, T.D.1
-
23
-
-
0035929121
-
Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
-
Ji, Y. B. et al. Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science 293, 2266-2269 (2001).
-
(2001)
Science
, vol.293
, pp. 2266-2269
-
-
Ji, Y.B.1
-
24
-
-
0035581737
-
Exploiting genomics to discover new antibiotics
-
McDevitt, D. & Rosenberg, M. Exploiting genomics to discover new antibiotics. Trends Microbiol. 9, 611-617 (2001).
-
(2001)
Trends Microbiol
, vol.9
, pp. 611-617
-
-
McDevitt, D.1
Rosenberg, M.2
-
25
-
-
0034835881
-
Better substrates for bacterial transglycosylases
-
Ye, X. Y. et al. Better substrates for bacterial transglycosylases. J. Am. Chem. Soc. 123, 3155-3156 (2001).
-
(2001)
J. Am. Chem. Soc.
, vol.123
, pp. 3155-3156
-
-
Ye, X.Y.1
-
26
-
-
0035805213
-
Crystal structure of the ribosome at 5.5-A resolution
-
Yusupov, M. M. et al. Crystal structure of the ribosome at 5.5-A resolution. Science 292, 883-896 (2001).
-
(2001)
Science
, vol.292
, pp. 883-896
-
-
Yusupov, M.M.1
-
27
-
-
0032969566
-
Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope
-
Navarre, W. W. & Schneewind, O. Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol. Mol. Biol. Rev. 63, 174-229 (1999).
-
(1999)
Microbiol. Mol. Biol. Rev.
, vol.63
, pp. 174-229
-
-
Navarre, W.W.1
Schneewind, O.2
-
28
-
-
0035283213
-
An embarrassment of sortases-a richness of substrates?
-
Pallen, M. J., Lam, A. C., Antonio, M. & Dunbar, K. An embarrassment of sortases-a richness of substrates? Trends Microbiol. 9, 97-102 (2001).
-
(2001)
Trends Microbiol
, vol.9
, pp. 97-102
-
-
Pallen, M.J.1
Lam, A.C.2
Antonio, M.3
Dunbar, K.4
-
29
-
-
0035478823
-
The non-mevalonate pathway of isoprenoids: Genes, enzymes, and intermediates
-
Rohdich, F., Kis, K., Bacher, A. & Eisenreich, W. The non-mevalonate pathway of isoprenoids: genes, enzymes, and intermediates. Curr. Opin. Chem. Biol. 5, 535-540 (2001).
-
(2001)
Curr. Opin. Chem. Biol.
, vol.5
, pp. 535-540
-
-
Rohdich, F.1
Kis, K.2
Bacher, A.3
Eisenreich, W.4
-
30
-
-
0034058528
-
Vancomcyin-resistant enterococcal infections
-
Murray, B. E. Vancomcyin-resistant enterococcal infections New Eng. J. Med. 342, 710-721 (2000).
-
(2000)
New Eng. J. Med
, vol.342
, pp. 710-721
-
-
Murray, B.E.1
-
31
-
-
0030711752
-
Evaluating treatment protocols to prevent antibiotic resistance
-
Bonhoeffer, S., Lipsitch, M. & Levin, B. R. Evaluating treatment protocols to prevent antibiotic resistance. Proc. Natl Acad. Sci. USA 94, 12106-12111 (1997).
-
(1997)
Proc. Natl Acad. Sci
, vol.94
, pp. 12106-12111
-
-
Bonhoeffer, S.1
Lipsitch, M.2
Levin, B.R.3
-
32
-
-
0031225237
-
Guidelines for the prevention of antimicrobial resistance in hospitals
-
Shlaes, D. et al. Guidelines for the prevention of antimicrobial resistance in hospitals. Clin. Infect. Dis. 25, 584-599 (1997).
-
(1997)
Clin. Infect. Dis.
, vol.25
, pp. 584-599
-
-
Shlaes, D.1
|