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Volumn 1, Issue 1, 2003, Pages 65-70

Opinion – anti-infectives: Where will new antibiotics come from?

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BIOLOGICAL PRODUCT;

EID: 0345839252     PISSN: 17401526     EISSN: 17401534     Source Type: Journal    
DOI: 10.1038/nrmicro727     Document Type: Article
Times cited : (636)

References (32)
  • 1
    • 0036499123 scopus 로고    scopus 로고
    • Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States: Results from the TRUST Surveillance Program, 1999-2000
    • Thornsberry, C. et al. Regional trends in antimicrobial resistance among clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis in the United States: results from the TRUST Surveillance Program, 1999-2000. Clin. Infect. Dis. 34, S4-S16 (2002).
    • (2002) Clin. Infect. Dis. , vol.34 , pp. S4-S16
    • Thornsberry, C.1
  • 2
    • 0035823272 scopus 로고    scopus 로고
    • Humans as the world's greatest evolutionary force
    • Palumbi, S. R. Humans as the world's greatest evolutionary force. Science 293, 1786-1790 (2001).
    • (2001) Science , vol.293 , pp. 1786-1790
    • Palumbi, S.R.1
  • 4
    • 0036834373 scopus 로고    scopus 로고
    • The future challenges facing the development of new antimicrobial drugs
    • Coates, A., Hu, Y, Bax, R. & Page, C. The future challenges facing the development of new antimicrobial drugs. Nature Rev. Drug Discov. 1, 895-910 (2002).
    • (2002) Nature Rev. Drug Discov. , vol.1 , pp. 895-910
    • Coates, A.1    Hu, Y.2    Bax, R.3    Page, C.4
  • 5
    • 0033790259 scopus 로고    scopus 로고
    • Development of daptomycin for gram-positive infections
    • Tally, F. P. & DeBruin, M. F. Development of daptomycin for gram-positive infections. J. Antimicrob. Chemother. 46, 523-526 (2000).
    • (2000) J. Antimicrob. Chemother. , vol.46 , pp. 523-526
    • Tally, F.P.1    Debruin, M.F.2
  • 6
    • 0035079979 scopus 로고    scopus 로고
    • Expression and isolation of small molecules from soil DNA libraries
    • MacNeil, I. A. et al. Expression and isolation of small molecules from soil DNA libraries. J. Mol. Microbiol. Biotechnol. 3, 301-308 (2001).
    • (2001) J. Mol. Microbiol. Biotechnol. , vol.3 , pp. 301-308
    • Macneil, I.A.1
  • 7
    • 4244059507 scopus 로고    scopus 로고
    • Harnessing the biosynthetic potential of modular polyketide synthases
    • Khosla, C. Harnessing the biosynthetic potential of modular polyketide synthases. Chem. Rev. 97, 2577-2590 (1997).
    • (1997) Chem. Rev. , vol.97 , pp. 2577-2590
    • Khosla, C.1
  • 8
    • 0032475992 scopus 로고    scopus 로고
    • Harnessing the biosynthetic code; combinations, permutations, and mutations
    • Cane, D. E., Walsh, C. T. & Khosla, C. Harnessing the biosynthetic code; combinations, permutations, and mutations. Science 282, 63-68 (1998).
    • (1998) Science , vol.282 , pp. 63-68
    • Cane, D.E.1    Walsh, C.T.2    Khosla, C.3
  • 9
    • 0029942660 scopus 로고    scopus 로고
    • Cotrimoxazole, rationale for re-examining its indications for use
    • Howe, R. A. & Spencer, R. C. Cotrimoxazole, rationale for re-examining its indications for use. Drug Saf. 14, 213-218 (1996).
    • (1996) Drug Saf , vol.14 , pp. 213-218
    • Howe, R.A.1    Spencer, R.C.2
  • 11
    • 0031105464 scopus 로고    scopus 로고
    • DNA Gyrase as a drug target
    • Maxwell, A. DNA Gyrase as a drug target. Trends Microbiol 5, 102-109 (1997).
    • (1997) Trends Microbiol , vol.5 , pp. 102-109
    • Maxwell, A.1
  • 12
    • 0035910436 scopus 로고    scopus 로고
    • Diversity-based organic synthesis in the era of genomics and proteomics
    • Arya, P D., Chou, T. H. & Baek, M. G. Diversity-based organic synthesis in the era of genomics and proteomics. Angew. Chem. Int. Ed. 40, 339-346 (2001).
    • (2001) Angew. Chem. Int. Ed. , vol.40 , pp. 339-346
    • Arya, P.D.1    Chou, T.H.2    Baek, M.G.3
  • 13
    • 0036008841 scopus 로고    scopus 로고
    • Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age
    • Arya, P D., Joseph, R. & Chou, D. T. Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age. Chem. Biol. 9, 145-146 (2002).
    • (2002) Chem. Biol. , vol.9 , pp. 145-146
    • Arya, P.D.1    Joseph, R.2    Chou, D.T.3
  • 14
    • 0034678033 scopus 로고    scopus 로고
    • Target-oriented and diversity-oriented organic synthesis in drug discovery
    • Schreiber, S. L. Target-oriented and diversity-oriented organic synthesis in drug discovery. Science 287, 1964-1969 (2000).
    • (2000) Science , vol.287 , pp. 1964-1969
    • Schreiber, S.L.1
  • 16
    • 0033515090 scopus 로고    scopus 로고
    • Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of "unnatural" natural products
    • McDaniel, R. A. et al. Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of "unnatural" natural products. Proc. Natl Acad. Sci. USA 96, 1846-1851 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 1846-1851
    • McDaniel, R.A.1
  • 17
    • 0036523418 scopus 로고    scopus 로고
    • Combinatorial biosynthesis of antibiotics: Challenges and opportunities
    • Walsh, C. T. Combinatorial biosynthesis of antibiotics: challenges and opportunities. Chem. Biochem. 3, 124-134 (2002).
    • (2002) Chem. Biochem. , vol.3 , pp. 124-134
    • Walsh, C.T.1
  • 18
    • 0034699519 scopus 로고    scopus 로고
    • Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
    • Carter, A. P. et al. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature 407, 340-348 (2000).
    • (2000) Nature , vol.407 , pp. 340-348
    • Carter, A.P.1
  • 19
    • 0036342198 scopus 로고    scopus 로고
    • The structures of four macrolide antibiotics bound to the large ribosomal subunit
    • Hansen, J. L. et al. The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol. Cell 10, 117-128 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 117-128
    • Hansen, J.L.1
  • 20
    • 17744377418 scopus 로고    scopus 로고
    • Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine, and IF3
    • Pioletti, M. et al. Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine, and IF3. EMBO J. 20, 1829-1839 (2001).
    • (2001) EMBO J , vol.20 , pp. 1829-1839
    • Pioletti, M.1
  • 21
    • 0035950132 scopus 로고    scopus 로고
    • Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
    • Schlunzen, F. R. et al. Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria. Nature 413, 814-821 (2001).
    • (2001) Nature , vol.413 , pp. 814-821
    • Schlunzen, F.R.1
  • 22
    • 0035166979 scopus 로고    scopus 로고
    • The comprehensive microbial resource
    • Peterson, T. D. et al. The comprehensive microbial resource. Nucl. Acids Res. 29, 123-125 (2001).
    • (2001) Nucl. Acids Res. , vol.29 , pp. 123-125
    • Peterson, T.D.1
  • 23
    • 0035929121 scopus 로고    scopus 로고
    • Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA
    • Ji, Y. B. et al. Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA. Science 293, 2266-2269 (2001).
    • (2001) Science , vol.293 , pp. 2266-2269
    • Ji, Y.B.1
  • 24
    • 0035581737 scopus 로고    scopus 로고
    • Exploiting genomics to discover new antibiotics
    • McDevitt, D. & Rosenberg, M. Exploiting genomics to discover new antibiotics. Trends Microbiol. 9, 611-617 (2001).
    • (2001) Trends Microbiol , vol.9 , pp. 611-617
    • McDevitt, D.1    Rosenberg, M.2
  • 25
    • 0034835881 scopus 로고    scopus 로고
    • Better substrates for bacterial transglycosylases
    • Ye, X. Y. et al. Better substrates for bacterial transglycosylases. J. Am. Chem. Soc. 123, 3155-3156 (2001).
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 3155-3156
    • Ye, X.Y.1
  • 26
    • 0035805213 scopus 로고    scopus 로고
    • Crystal structure of the ribosome at 5.5-A resolution
    • Yusupov, M. M. et al. Crystal structure of the ribosome at 5.5-A resolution. Science 292, 883-896 (2001).
    • (2001) Science , vol.292 , pp. 883-896
    • Yusupov, M.M.1
  • 27
    • 0032969566 scopus 로고    scopus 로고
    • Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope
    • Navarre, W. W. & Schneewind, O. Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol. Mol. Biol. Rev. 63, 174-229 (1999).
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 174-229
    • Navarre, W.W.1    Schneewind, O.2
  • 28
    • 0035283213 scopus 로고    scopus 로고
    • An embarrassment of sortases-a richness of substrates?
    • Pallen, M. J., Lam, A. C., Antonio, M. & Dunbar, K. An embarrassment of sortases-a richness of substrates? Trends Microbiol. 9, 97-102 (2001).
    • (2001) Trends Microbiol , vol.9 , pp. 97-102
    • Pallen, M.J.1    Lam, A.C.2    Antonio, M.3    Dunbar, K.4
  • 29
    • 0035478823 scopus 로고    scopus 로고
    • The non-mevalonate pathway of isoprenoids: Genes, enzymes, and intermediates
    • Rohdich, F., Kis, K., Bacher, A. & Eisenreich, W. The non-mevalonate pathway of isoprenoids: genes, enzymes, and intermediates. Curr. Opin. Chem. Biol. 5, 535-540 (2001).
    • (2001) Curr. Opin. Chem. Biol. , vol.5 , pp. 535-540
    • Rohdich, F.1    Kis, K.2    Bacher, A.3    Eisenreich, W.4
  • 30
    • 0034058528 scopus 로고    scopus 로고
    • Vancomcyin-resistant enterococcal infections
    • Murray, B. E. Vancomcyin-resistant enterococcal infections New Eng. J. Med. 342, 710-721 (2000).
    • (2000) New Eng. J. Med , vol.342 , pp. 710-721
    • Murray, B.E.1
  • 31
    • 0030711752 scopus 로고    scopus 로고
    • Evaluating treatment protocols to prevent antibiotic resistance
    • Bonhoeffer, S., Lipsitch, M. & Levin, B. R. Evaluating treatment protocols to prevent antibiotic resistance. Proc. Natl Acad. Sci. USA 94, 12106-12111 (1997).
    • (1997) Proc. Natl Acad. Sci , vol.94 , pp. 12106-12111
    • Bonhoeffer, S.1    Lipsitch, M.2    Levin, B.R.3
  • 32
    • 0031225237 scopus 로고    scopus 로고
    • Guidelines for the prevention of antimicrobial resistance in hospitals
    • Shlaes, D. et al. Guidelines for the prevention of antimicrobial resistance in hospitals. Clin. Infect. Dis. 25, 584-599 (1997).
    • (1997) Clin. Infect. Dis. , vol.25 , pp. 584-599
    • Shlaes, D.1


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