Engineered affinity proteins for tumour-targeting applications

Biotechnology and Applied Biochemistry

Volumn 53, Issue 1, 2009, Pages 1-29

  Friedman, Mikaela ^a   Ståhl, Stefan ^a  

^a ALBANOVA UNIVERSITY CENTER   (Sweden)

Author keywords

Affibody molecule (Affibody molecule); Affinity proteins; Epidermal growth factor receptor family (ErbB family); Molecular imaging; Radiotherapy; Tumour targeting

Indexed keywords

AFFINITY PROTEINS; CLINICAL ONCOLOGY; CLINICAL USE; CONVENTIONAL TREATMENTS; CYTOTOXIC EFFECTS; EPIDERMAL GROWTH FACTOR RECEPTORS; EPIDERMAL-GROWTH-FACTOR-RECEPTOR FAMILY (ERBB FAMILY); HIGH-THROUGHPUT; IN-VITRO; IN-VIVO; MOLECULAR IMAGING; NORMAL TISSUE; PATIENT PROGNOSIS; RADIATION THERAPY; SCAFFOLD PROTEIN; SINGLE DOMAINS; TREATMENT MODALITY; TUMOUR PROGRESSION; TUMOUR TARGETING; TUMOURS;

ANTIGENS; BIOACTIVITY; CHEMOTHERAPY; GENETIC ENGINEERING; HISTOLOGY; MOLECULES; MONOCLONAL ANTIBODIES; ONCOLOGY; PEPTIDES; RADIOISOTOPES; RADIOTHERAPY; SCAFFOLDS; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

TUMORS;

ALEMTUZUMAB; ANTINEOPLASTIC AGENT; BEVACIZUMAB; CAPROMAB PENDETIDE IN 111; CARBON 11; CETUXIMAB; CP 751871; EDRECOLOMAB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERLOTINIB; FLUORODEOXYGLUCOSE F 18; GALLIUM 67; GALLIUM 68; GEFITINIB; GEMTUZUMAB OZOGAMICIN; IBRITUMOMAB TIUXETAN; INDIUM 111; IODINE 123; LAPATINIB; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B.72.3; ONCOSCINT; PANITUMUMAB; PENTETREOTIDE; PERTUZUMAB; RITUXIMAB; TECHNETIUM 99M; TOSITUMOMAB I 131; TRASTUZUMAB; TUMOR ANTIGEN; UNCLASSIFIED DRUG; UNINDEXED DRUG; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERBB2 PROTEIN, HUMAN; HYBRID PROTEIN; RADIOISOTOPE;

ACUTE GRANULOCYTIC LEUKEMIA; ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ANTIBODY PRODUCTION; ANTINEOPLASTIC ACTIVITY; B CELL LEUKEMIA; BREAST CANCER; CANCER GENE THERAPY; CANCER RADIOTHERAPY; CANCER RESEARCH; CELL FREE SYSTEM; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL TRIAL; COLON CANCER; COLORECTAL CANCER; CYTOTOXICITY; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TARGETING; DRUG TOLERABILITY; GENETIC ENGINEERING; HEAD AND NECK CANCER; HUMAN; LUNG NON SMALL CELL CANCER; MOLECULAR IMAGING; NONHODGKIN LYMPHOMA; NONHUMAN; PHAGE DISPLAY; POSITRON EMISSION TOMOGRAPHY; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; RADIOIMMUNOTHERAPY; REVIEW; SIGNAL TRANSDUCTION; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SOLID TUMOR; TUMOR GROWTH; METABOLISM; NEOPLASM; SCINTISCANNING;

PLEURONECTIDAE;

ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; HUMANS; NEOPLASMS; PROTEIN ENGINEERING; RADIOISOTOPES; RADIONUCLIDE IMAGING; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS;

EID: 65649127261     PISSN: 08854513     EISSN: None     Source Type: Journal    
DOI: 10.1042/BA20080287     Document Type: Review

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