Development of a human light chain variable domain (VL) intracellular antibody specific for the amino terminus of huntingtin via yeast surface display

Journal of Molecular Biology

Volumn 342, Issue 3, 2004, Pages 901-912

  Colby, David W ^a   Garg, Payal ^b   Holden, Tina ^b   Chao, Ginger ^a   Webster, Jack M ^c   Messer, Anne ^c,d   Ingram, Vernon M ^b   Wittrup, K Dane ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c WADSWORTH CENTER   (United States)

^d STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Huntington's disease; intracellular antibody; paratope mapping; single domain antibody; yeast surface display

Indexed keywords

HUNTINGTIN; PROTEIN ANTIBODY;

AMINO TERMINAL SEQUENCE; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; CELL CULTURE; CONTROLLED STUDY; CYTOPLASM; EMBRYO; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; STATISTICAL SIGNIFICANCE; YEAST;

MAMMALIA;

EID: 4444239017     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.07.054     Document Type: Article

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