Intracellular antibodies as specific reagents for functional ablation: Future therapeutic molecules

Current Molecular Medicine

Volumn 4, Issue 5, 2004, Pages 519-528

  Lobato, M N ^a   Rabbitts, T H ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

AIDS; Cancer; IDab; Intrabodies; Intracellular antibodies; scFv; Therapy

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; CELL ANTIBODY; CELL PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; INTRACELLULAR ANTIBODY; MONOCLONAL ANTIBODY; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY AFFINITY; ANTIBODY COMBINING SITE; ANTIBODY ENGINEERING; ANTIBODY ISOLATION; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN RECOGNITION; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; CELLULAR DISTRIBUTION; CLINICAL TRIAL; DRUG DELIVERY SYSTEM; DRUG MECHANISM; HUMAN; MOLECULAR STABILITY; NONHUMAN; OVARY CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; VIRAL GENE DELIVERY SYSTEM;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; CLINICAL TRIALS; GENE THERAPY; HIV-1; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOTHERAPY; NEOPLASMS; NEURODEGENERATIVE DISEASES; PHARMACEUTICAL PREPARATIONS;

EID: 3242707674     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/1566524043360384     Document Type: Review

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