-
1
-
-
18544408628
-
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial
-
Alvarez R.D., Barnes M.N., Gomez-Navarro J., Wang M., Strong T.V., Arafat W., Arani R.B., Johnson M.R., Roberts B.L., Siegal G.P., and Curiel D.T. A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial. Clin. Cancer Res. 6 (2000) 3081
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3081
-
-
Alvarez, R.D.1
Barnes, M.N.2
Gomez-Navarro, J.3
Wang, M.4
Strong, T.V.5
Arafat, W.6
Arani, R.B.7
Johnson, M.R.8
Roberts, B.L.9
Siegal, G.P.10
Curiel, D.T.11
-
2
-
-
0028148050
-
Intracellular expression of single chain antibodies reverts ErbB-2 transformation
-
Beerli R.R., Wels W., and Hynes N.E. Intracellular expression of single chain antibodies reverts ErbB-2 transformation. J. Biol. Chem. 269 (1994) 23931
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23931
-
-
Beerli, R.R.1
Wels, W.2
Hynes, N.E.3
-
3
-
-
23644452792
-
Engineered proteins as specific binding reagents
-
Binz H.K., and Pluckthun A. Engineered proteins as specific binding reagents. Curr. Opin. Biotechnol. 16 (2005) 459
-
(2005)
Curr. Opin. Biotechnol.
, vol.16
, pp. 459
-
-
Binz, H.K.1
Pluckthun, A.2
-
4
-
-
27144511241
-
Engineering novel binding proteins from nonimmunoglobulin domains
-
Binz H.K., Amstutz P., and Pluckthun A. Engineering novel binding proteins from nonimmunoglobulin domains. Nat. Biotechnol. 23 (2005) 1257
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 1257
-
-
Binz, H.K.1
Amstutz, P.2
Pluckthun, A.3
-
5
-
-
0344825125
-
Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines
-
Choudhury A., Charo J., Parapuram S.K., Hunt R.C., Hunt D.M., Seliger B., and Kiessling R. Small interfering RNA (siRNA) inhibits the expression of the Her2/neu gene, upregulates HLA class I and induces apoptosis of Her2/neu positive tumor cell lines. Int. J. Cancer 108 (2004) 71
-
(2004)
Int. J. Cancer
, vol.108
, pp. 71
-
-
Choudhury, A.1
Charo, J.2
Parapuram, S.K.3
Hunt, R.C.4
Hunt, D.M.5
Seliger, B.6
Kiessling, R.7
-
6
-
-
0004083736
-
-
Oxford university press, Oxford
-
Davis J.M. Basic cell culture (2002), Oxford university press, Oxford
-
(2002)
Basic cell culture
-
-
Davis, J.M.1
-
7
-
-
0028500163
-
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines
-
Deshane J., Loechel F., Conry R.M., Siegal G.P., King C.R., and Curiel D.T. Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines. Gene Ther. 1 (1994) 332
-
(1994)
Gene Ther.
, vol.1
, pp. 332
-
-
Deshane, J.1
Loechel, F.2
Conry, R.M.3
Siegal, G.P.4
King, C.R.5
Curiel, D.T.6
-
8
-
-
0028823836
-
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody
-
Deshane J., Cabrera G., Grim J.E., Siegal G.P., Pike J., Alvarez R.D., and Curiel D.T. Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody. Gynecol. Oncol. 59 (1995) 8
-
(1995)
Gynecol. Oncol.
, vol.59
, pp. 8
-
-
Deshane, J.1
Cabrera, G.2
Grim, J.E.3
Siegal, G.P.4
Pike, J.5
Alvarez, R.D.6
Curiel, D.T.7
-
9
-
-
33646739287
-
Effects of HER2-binding affibody molecules on intracellular signaling pathways
-
Ekerljung L., Steffen A.C., Carlsson J., and Lennartsson J. Effects of HER2-binding affibody molecules on intracellular signaling pathways. Tumour Biol. 27 (2006) 201
-
(2006)
Tumour Biol.
, vol.27
, pp. 201
-
-
Ekerljung, L.1
Steffen, A.C.2
Carlsson, J.3
Lennartsson, J.4
-
10
-
-
34347380371
-
Phage display selection of affibody molecules with specific binding to the extracellular domain of the epidermal growth factor receptor
-
Friedman M., Nordberg E., Hoiden-Guthenberg I., Brismar H., Adams G.P., Nilsson F.Y., Carlsson J., and Stahl S. Phage display selection of affibody molecules with specific binding to the extracellular domain of the epidermal growth factor receptor. Protein Eng. Des. Sel. 4 (2007) 189
-
(2007)
Protein Eng. Des. Sel.
, vol.4
, pp. 189
-
-
Friedman, M.1
Nordberg, E.2
Hoiden-Guthenberg, I.3
Brismar, H.4
Adams, G.P.5
Nilsson, F.Y.6
Carlsson, J.7
Stahl, S.8
-
11
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta D., Beerli R.R., Daly J.M., and Hynes N.E. ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J. 16 (1997) 1647
-
(1997)
EMBO J.
, vol.16
, pp. 1647
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
12
-
-
33845665382
-
Selection and characterization of affibody ligands binding to Alzheimer amyloid beta peptides
-
Gronwall C., Jonsson A., Lindstrom S., Gunneriusson E., Stahl S., and Herne N. Selection and characterization of affibody ligands binding to Alzheimer amyloid beta peptides. J. Biotechnol. 128 (2007) 162
-
(2007)
J. Biotechnol.
, vol.128
, pp. 162
-
-
Gronwall, C.1
Jonsson, A.2
Lindstrom, S.3
Gunneriusson, E.4
Stahl, S.5
Herne, N.6
-
13
-
-
0032717780
-
Affinity maturation of a Taq DNA polymerase specific affibody by helix shuffling
-
Gunneriusson E., Nord K., Uhlen M., and Nygren P. Affinity maturation of a Taq DNA polymerase specific affibody by helix shuffling. Protein Eng. 12 (1999) 873
-
(1999)
Protein Eng.
, vol.12
, pp. 873
-
-
Gunneriusson, E.1
Nord, K.2
Uhlen, M.3
Nygren, P.4
-
14
-
-
22844446276
-
Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells
-
Hu Y.P., Venkateswarlu S., Sergina N., Howell G., St Clair P., Humphrey L.E., Li W., Hauser J., Zborowska E., Willson J.K., and Brattain M.G. Reorganization of ErbB family and cell survival signaling after Knock-down of ErbB2 in colon cancer cells. J. Biol. Chem. 280 (2005) 27383
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27383
-
-
Hu, Y.P.1
Venkateswarlu, S.2
Sergina, N.3
Howell, G.4
St Clair, P.5
Humphrey, L.E.6
Li, W.7
Hauser, J.8
Zborowska, E.9
Willson, J.K.10
Brattain, M.G.11
-
15
-
-
0029812091
-
Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumor cells
-
Jannot C.B., Beerli R.R., Mason S., Gullick W.J., and Hynes N.E. Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumor cells. Oncogene 13 (1996) 275
-
(1996)
Oncogene
, vol.13
, pp. 275
-
-
Jannot, C.B.1
Beerli, R.R.2
Mason, S.3
Gullick, W.J.4
Hynes, N.E.5
-
16
-
-
0034658319
-
Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines
-
Klein C., Bueler H., and Mulligan R.C. Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines. J. Exp. Med. 191 (2000) 1699
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1699
-
-
Klein, C.1
Bueler, H.2
Mulligan, R.C.3
-
17
-
-
33846244218
-
Site-specifically conjugated anti-HER2 affibody molecules as one-step reagents for target expression analyses on cells and xenograft samples
-
Lundberg E., Hoiden-Guthenberg I., Larsson B., Uhlen M., and Graslund T. Site-specifically conjugated anti-HER2 affibody molecules as one-step reagents for target expression analyses on cells and xenograft samples. J. Immunol. Methods 319 (2007) 53
-
(2007)
J. Immunol. Methods
, vol.319
, pp. 53
-
-
Lundberg, E.1
Hoiden-Guthenberg, I.2
Larsson, B.3
Uhlen, M.4
Graslund, T.5
-
18
-
-
0023652396
-
A C-terminal signal prevents secretion of luminal ER proteins
-
Munro S., and Pelham H.R. A C-terminal signal prevents secretion of luminal ER proteins. Cell 48 (1987) 899
-
(1987)
Cell
, vol.48
, pp. 899
-
-
Munro, S.1
Pelham, H.R.2
-
19
-
-
0028982245
-
A combinatorial library of an alpha-helical bacterial receptor domain
-
Nord K., Nilsson J., Nilsson B., Uhlen M., and Nygren P.A. A combinatorial library of an alpha-helical bacterial receptor domain. Protein Eng. 8 (1995) 601
-
(1995)
Protein Eng.
, vol.8
, pp. 601
-
-
Nord, K.1
Nilsson, J.2
Nilsson, B.3
Uhlen, M.4
Nygren, P.A.5
-
20
-
-
0030835822
-
Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain
-
Nord K., Gunneriusson E., Ringdahl J., Stahl S., Uhlen M., and Nygren P.A. Binding proteins selected from combinatorial libraries of an alpha-helical bacterial receptor domain. Nat. Biotechnol. 15 (1997) 772
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 772
-
-
Nord, K.1
Gunneriusson, E.2
Ringdahl, J.3
Stahl, S.4
Uhlen, M.5
Nygren, P.A.6
-
21
-
-
0034832744
-
Recombinant human factor VIII-specific affinity ligands selected from phage-displayed combinatorial libraries of protein A
-
Nord K., Nord O., Uhlen M., Kelley B., Ljungqvist C., and Nygren P.A. Recombinant human factor VIII-specific affinity ligands selected from phage-displayed combinatorial libraries of protein A. Eur. J. Biochem. 268 (2001) 4269
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 4269
-
-
Nord, K.1
Nord, O.2
Uhlen, M.3
Kelley, B.4
Ljungqvist, C.5
Nygren, P.A.6
-
22
-
-
3142677981
-
Binding proteins from alternative scaffolds
-
Nygren P.A., and Skerra A. Binding proteins from alternative scaffolds. J. Immunol. Methods 290 (2004) 3
-
(2004)
J. Immunol. Methods
, vol.290
, pp. 3
-
-
Nygren, P.A.1
Skerra, A.2
-
23
-
-
33646261864
-
Tumor imaging using a picomolar affinity HER2 binding affibody molecule
-
Orlova A., Magnusson M., Eriksson T.L., Nilsson M., Larsson B., Hoiden-Guthenberg I., Widstrom C., Carlsson J., Tolmachev V., Stahl S., and Nilsson F.Y. Tumor imaging using a picomolar affinity HER2 binding affibody molecule. Cancer Res. 66 (2006) 4339
-
(2006)
Cancer Res.
, vol.66
, pp. 4339
-
-
Orlova, A.1
Magnusson, M.2
Eriksson, T.L.3
Nilsson, M.4
Larsson, B.5
Hoiden-Guthenberg, I.6
Widstrom, C.7
Carlsson, J.8
Tolmachev, V.9
Stahl, S.10
Nilsson, F.Y.11
-
24
-
-
15444374558
-
beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide
-
Paganetti P., Calanca V., Galli C., Stefani M., and Molinari M. beta-site specific intrabodies to decrease and prevent generation of Alzheimer's Abeta peptide. J. Cell Biol. 168 (2005) 863
-
(2005)
J. Cell Biol.
, vol.168
, pp. 863
-
-
Paganetti, P.1
Calanca, V.2
Galli, C.3
Stefani, M.4
Molinari, M.5
-
26
-
-
0030450784
-
The dynamic organisation of the secretory pathway
-
Pelham H.R. The dynamic organisation of the secretory pathway. Cell Struct. Funct. 21 (1996) 413
-
(1996)
Cell Struct. Funct.
, vol.21
, pp. 413
-
-
Pelham, H.R.1
-
27
-
-
0036275295
-
Human immunoglobulin A (IgA)-specific ligands from combinatorial engineering of protein A
-
Ronnmark J., Gronlund H., Uhlen M., and Nygren P.A. Human immunoglobulin A (IgA)-specific ligands from combinatorial engineering of protein A. Eur. J. Biochem. 269 (2002) 2647
-
(2002)
Eur. J. Biochem.
, vol.269
, pp. 2647
-
-
Ronnmark, J.1
Gronlund, H.2
Uhlen, M.3
Nygren, P.A.4
-
28
-
-
0142184270
-
Inhibition of the CD28-CD80 co-stimulation signal by a CD28-binding affibody ligand developed by combinatorial protein engineering
-
Sandstrom K., Xu Z., Forsberg G., and Nygren P.A. Inhibition of the CD28-CD80 co-stimulation signal by a CD28-binding affibody ligand developed by combinatorial protein engineering. Protein Eng. 16 (2003) 691
-
(2003)
Protein Eng.
, vol.16
, pp. 691
-
-
Sandstrom, K.1
Xu, Z.2
Forsberg, G.3
Nygren, P.A.4
-
29
-
-
37049183697
-
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., and McGuire W.L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235 (1987) 177
-
(1987)
Science
, vol.235
, pp. 177
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
30
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon D.J., Godolphin W., Jones L.A., Holt J.A., Wong S.G., Keith D.E., Levin W.J., Stuart S.G., Udove J., Ullrich A., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244 (1989) 707
-
(1989)
Science
, vol.244
, pp. 707
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
Holt, J.A.4
Wong, S.G.5
Keith, D.E.6
Levin, W.J.7
Stuart, S.G.8
Udove, J.9
Ullrich, A.10
-
31
-
-
0034681197
-
Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion
-
Steinberger P., Andris-Widhopf J., Buhler B., Torbett B.E., and Barbas III C.F. Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 805
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 805
-
-
Steinberger, P.1
Andris-Widhopf, J.2
Buhler, B.3
Torbett, B.E.4
Barbas III, C.F.5
-
32
-
-
33947672248
-
Radionuclide therapy of HER2-positive microxenografts using a 177Lu-labeled HER2-specific Affibody molecule
-
Tolmachev V., Orlova A., Pehrson R., Galli J., Baastrup B., Andersson K., Sandstrom M., Rosik D., Carlsson J., Lundqvist H., Wennborg A., and Nilsson F.Y. Radionuclide therapy of HER2-positive microxenografts using a 177Lu-labeled HER2-specific Affibody molecule. Cancer Res. 67 (2007) 2773
-
(2007)
Cancer Res.
, vol.67
, pp. 2773
-
-
Tolmachev, V.1
Orlova, A.2
Pehrson, R.3
Galli, J.4
Baastrup, B.5
Andersson, K.6
Sandstrom, M.7
Rosik, D.8
Carlsson, J.9
Lundqvist, H.10
Wennborg, A.11
Nilsson, F.Y.12
-
33
-
-
4644247278
-
Selection and characterization of HER2/neu-binding affibody ligands
-
Wikman M., Steffen A.C., Gunneriusson E., Tolmachev V., Adams G.P., Carlsson J., and Stahl S. Selection and characterization of HER2/neu-binding affibody ligands. Protein Eng. Des. Sel. 17 (2004) 455
-
(2004)
Protein Eng. Des. Sel.
, vol.17
, pp. 455
-
-
Wikman, M.1
Steffen, A.C.2
Gunneriusson, E.3
Tolmachev, V.4
Adams, G.P.5
Carlsson, J.6
Stahl, S.7
-
34
-
-
33748525178
-
Selection and characterization of an HIV-1 gp120-binding affibody ligand
-
Wikman M., Rowcliffe E., Friedman M., Henning P., Lindholm L., Olofsson S., and Stahl S. Selection and characterization of an HIV-1 gp120-binding affibody ligand. Biotechnol. Appl. Biochem. 45 (2006) 93
-
(2006)
Biotechnol. Appl. Biochem.
, vol.45
, pp. 93
-
-
Wikman, M.1
Rowcliffe, E.2
Friedman, M.3
Henning, P.4
Lindholm, L.5
Olofsson, S.6
Stahl, S.7
-
35
-
-
23844510061
-
Anti-erbB-2 antibody trastuzumab in the treatment of HER2-amplified breast cancer
-
Yeon C.H., and Pegram M.D. Anti-erbB-2 antibody trastuzumab in the treatment of HER2-amplified breast cancer. Invest. New Drugs 23 (2005) 391
-
(2005)
Invest. New Drugs
, vol.23
, pp. 391
-
-
Yeon, C.H.1
Pegram, M.D.2
|