Highly effective recombinant format of a humanized IgG-like bispecific antibody for cancer immunotherapy with retargeting of lymphocytes to tumor cells

Journal of Biological Chemistry

Volumn 282, Issue 38, 2007, Pages 27659-27665

  Asano, Ryutaro ^a   Watanabe, Yasuhiro ^b   Kawaguchi, Hiroko ^a   Fukazawa, Hidesuke ^c   Nakanishi, Takeshi ^a   Umetsu, Mitsuo ^a   Hayashi, Hiroki ^b   Katayose, Yu ^b   Unno, Michiaki ^b   Kudo, Toshio ^a   Kumagai, Izumi ^a,d  

^a TOHOKU UNIVERSITY   (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; CELL GROWTH; GROWTH KINETICS; IMMUNOLOGY; TUMORS;

ANTITUMOR ACTIVITY; GROWTH FACTOR RECEPTOR; LYMPHOCYTES;

TOXIC MATERIALS;

BISPECIFIC ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR; IMMUNOGLOBULIN G ANTIBODY; RECOMBINANT ANTIBODY;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER IMMUNOTHERAPY; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; EFFECTOR CELL; ENZYME ASSAY; FLOW CYTOMETRY; GROWTH INHIBITION; LYMPHOCYTE; LYMPHOKINE ACTIVATED KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PHOSPHORYLATION; PRIORITY JOURNAL; RECEPTOR BINDING; T LYMPHOCYTE; TUMOR CELL;

MAMMALIA;

EID: 34948911585     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704719200     Document Type: Article

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