Small antibody-like proteins with prescribed ligand specificities derived from the lipocalin fold

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 1898-1903

  Beste, Gerald ^a,b   Schmidt, Frank S ^a,c   Stibora, Thomas ^a,d   Skerra, Arne ^a,e  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

^b Xerion Pharmaceuticals AG   (Germany)

^c SANOFI   (France)

^d Gesell F Biotechnologische E   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; FLUORESCEIN; LIPOCALIN; PEPTIDE LIBRARY;

ARTICLE; BINDING AFFINITY; BINDING SITE; BUTTERFLY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, CATALYTIC; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CLONING, MOLECULAR; GENE LIBRARY; INSECT HORMONES; INSECT PROTEINS; INSECTS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

ARACHNIDA; BACTERIA (MICROORGANISMS); HEXAPODA; PIERIS BRASSICAE;

EID: 0033515005     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.1898     Document Type: Article

References (34)

1. Skerra, A. (1993) Curr. Opin. Immunol. 5, 256-262.
2. Winter, G. & Milstein, C. (1991) Nature (London) 349, 293-299.
3. Hoogenboom, H. R. (1997) Trends Biotechnol. 15, 62-70.
4. Flower, D. R. (1996) Biochem. J. 318, 1-14.
5. Huber, R., Schneider, M., Mayr, L, Müller, R., Deutzmann, R., Suter, F., Zuber, H., Falk, H. & Kayser, H. (1987) J. Mol. Biol. 198, 499-513.
6. Cowan, S. W., Newcomer, M. E. & Jones, T. A. (1990) Proteins Struct. Funct. Genet. 8, 44-61.
7. Böcskei, Z., Groom, C. R., Flower, D. R., Wright, C. E., Phillips, S. E. V., Cavaggioni, A., Findlay, J. B. C. & North, A. C. T. (1992) Nature (London) 360, 186-188.
8. Newcomer, M. E. (1993) Structure 1, 7-18.
9. Schmidt, F. S. & Skerra, A. (1994) Eur. J. Biochem. 219, 855-863.
10. Ogamo, A., Matsuzaki, K., Uchiyama, H. & Nagasawa, K. (1982) Carbohydrate Res. 105, 69-85.
11. Skerra, A. (1994) Gene 151, 131-135.
12. Schmidt, T. G. M., Koepke, J., Frank, R. & Skerra, A. (1996) J. Mol. Biol. 255, 753-766.
13. Kay, B. K., Winter, J. & McCafferty, J. (1996) Phage Display of Peptides and Proteins: A Laboratory Manual (Academic, San Diego).
14. Tung, W. L. & Chow, K. C. (1995) Trends Genet. 11, 128-129.
15. Schmidt, A. M., Bloß, I. & Skerra, A. (1998) Protein Eng. 11, 601-607.
16. Voss, S. & Skerra, A. (1997) Protein Eng. 10, 975-982.
17. Gill, S. C. & von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326.
18. Fling, S. P. & Gregerson, D. S. (1986) Anal. Biochem. 155, 83-88.
19. Geisselsoder, J., Witney, F. & Yuckenberg, P. (1987) BioTechniques 5, 786-791.
20. Voss, E. W., Jr. (1984) Fluorescein Hapten: An Immunological Probe (CRC, Boca Raton, FL).
21. Denzin, L. K., Whitlow, M. & Voss, E. W., Jr. (1991) J. Biol. Chem. 266, 14095-14103.
22. Herron, J. N., He, X., Mason, M. L., Voss, E. W., Jr. & Edmundson, A. B. (1989) Proteins Struct. Funct. Genet. 5, 271-280.
23. Barbas, C. F., III, Bain, J. D., Hoekstra, D. M. & Lerner, R. A. (1992) Proc. Natl. Acad. Sci. USA 89, 4457-4461.
24. Whitlow, M., Howard, A. J., Wood, J. F., Voss, E. W., Jr., & Hardman, K. D. (1995) Protein Eng. 8, 749-761.
25. Ponder, J. W. & Richards, F. M. (1987) J. Mol. Biol. 193, 775-791.
26. Harmer, I. J. & Samuel, D. (1989) J. Immunol. Methods 122, 115-121.
27. Bar-Noy, S., Darmon, A., Ginsberg, H. & Cabantchik, Z. I. (1984) Biochim. Biophys. Acta 778, 612-614.
28. Low, N. M., Holliger, P. & Winter, G. (1996) J. Mol. Biol. 260, 359-368.
29. Barbas, C. F., III, & Burton, D. R. (1996) Trends Biotechnol. 14, 230-234.
30. Nygren, P.-Å. & Uhlén, M. (1997) Curr. Opin. Struct. Biol. 7, 463-469.
31. Davies, J. & Riechmann, L. (1994) Biotechnology 13, 475-479.
32. Smith, G. P., Patel, S. U., Windass, J. D., Thornton, J. M., Winter, G. & Griffiths, A. D. (1998) J. Mol. Biol. 277, 317-332.
33. Ku, J. & Schultz, P. G. (1995) Proc. Natl. Acad. Sci. USA 92, 6552-6556.
34. Monaco, H. L., Rizzi, M. & Coda, A. (1995) Science 268, 1039-1041.