Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism

Structure

Volumn 15, Issue 5, 2007, Pages 625-636

  Schweizer, Andreas ^a,b   Roschitzki Voser, Heidi ^a   Amstutz, Patrick ^a,c   Briand, Christophe ^a   Gulotti Georgieva, Maya ^a   Prenosil, Eva ^a   Binz, H Kaspar ^a,c   Capitani, Guido ^a   Baici, Antonio ^a   Plückthun, Andreas ^a   Grütter, Markus G ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Hospital Epidemiology   (Switzerland)

^c MOLECULAR PARTNERS AG   (Switzerland)

Author keywords

CELLCYCLE; CHEMBIOL

Indexed keywords

ANKYRIN; CASPASE 2; CASPASE INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME INHIBITION; ENZYME SPECIFICITY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANKYRIN REPEAT; CASPASE 2; CYSTEINE ENDOPEPTIDASES; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING;

EID: 34247853389     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.str.2007.03.014     Document Type: Article

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