Exploiting recombination in single bacteria to make large phage antibody libraries

Nature Biotechnology

Volumn 18, Issue 1, 2000, Pages 75-80

  Sblattero, Daniele ^a   Bradbury, Andrew ^a,b  

^a SISSA   (Italy)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

Antibody engineering; Cre recombinase; Filamentous phage; Phage display; Recombination; Single chain Fv (scFv)

Indexed keywords

ANTIBODY; ANTIGEN; RECOMBINASE;

ANTIBODY SPECIFICITY; ANTIGEN SPECIFICITY; ARTICLE; BACTERIOPHAGE; CONTROLLED STUDY; GENETIC ENGINEERING; GENETIC RECOMBINATION; NONHUMAN; PHAGE DISPLAY; PHAGEMID; PRIORITY JOURNAL;

ANTIBODIES; ANTIBODY DIVERSITY; ANTIBODY SPECIFICITY; ANTIGENS; ATTACHMENT SITES, MICROBIOLOGICAL; BACTERIOPHAGES; BINDING SITES, ANTIBODY; CLONING, MOLECULAR; ESCHERICHIA COLI; GENE REARRANGEMENT; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN FRAGMENTS; INTEGRASES; PEPTIDE LIBRARY; RECOMBINATION, GENETIC; REPRODUCIBILITY OF RESULTS; SEQUENCE ANALYSIS, DNA; VIRAL PROTEINS;

UNIDENTIFIED BACTERIOPHAGE;

EID: 0033987925     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/71958     Document Type: Article

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