Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival

PLoS Biology

Volumn 6, Issue 7, 2008, Pages 1508-1526

  Wang, Qi ^a   Johnson, Joshua L ^a   Agar, Nathalie Y R ^b   Agar, Jeffrey N ^a  

^a BRANDEIS UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CONCENTRATION (PARAMETERS); HUMAN; MAJOR CLINICAL STUDY; MOTONEURON; PROTEIN AGGREGATION; PROTEIN STABILITY; SPINAL CORD; SURVIVAL; SURVIVAL TIME; ALGORITHM; CHEMICAL PHENOMENA; CHEMISTRY; ENZYME STABILITY; ENZYMOLOGY; FAMILY HEALTH; GENETICS; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; RISK FACTOR;

ADULT; AGED; ALGORITHMS; AMYOTROPHIC LATERAL SCLEROSIS; ENZYME STABILITY; FAMILY HEALTH; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KAPLAN-MEIER ESTIMATE; MIDDLE AGED; MUTATION; PROTEIN DENATURATION; PROTEIN FOLDING; RISK FACTORS; SUPEROXIDE DISMUTASE;

EID: 48349090111     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0060170     Document Type: Article

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