Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 35, 2007, Pages 14157-14162

  Zetterström, Per ^a   Stewart, Heather G ^a,b   Bergemalm, Daniel ^a   Jonsson, P Andreas ^a   Graffmo, Karin S ^a   Andersen, Peter M ^a   Brännström, Thomas ^a   Oliveberg, Mikael ^c   Marklund, Stefan L ^a  

^a UMEÅ UNIVERSITY   (Sweden)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Disulfide bond; Motor neuron; Neurodegeneration

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; PROTEIN SUBUNIT; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DISULFIDE BOND; MOLECULAR SIZE; MOTONEURON; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; SPINAL CORD; ANIMAL; DISEASE MODEL; ENZYMOLOGY; GENE DELETION; GENETIC VARIABILITY; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MOTOR NEURON DISEASE; MUTATION; OXIDATION REDUCTION REACTION; PATHOPHYSIOLOGY; PROTEIN DENATURATION; TRANSGENIC MOUSE;

MURINAE;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURON DISEASE; MUTATION; OXIDATION-REDUCTION; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN SUBUNITS; SEQUENCE DELETION; SPINAL CORD; SUPEROXIDE DISMUTASE; VARIATION (GENETICS);

EID: 35348874857     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0700477104     Document Type: Article

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