Analysis of the cytosolic proteome in a cell culture model of familial amyotrophic lateral sclerosis reveals alterations to the proteasome, antioxidant defenses, and nitric oxide synthetic pathways

Journal of Biological Chemistry

Volumn 278, Issue 8, 2003, Pages 6371-6383

  Allen, Simon ^a   Heath, Paul Roy ^a   Kirby, Janine ^a   Wharton, Stephen Barrie ^a   Cookson, Mark Robert ^b   Menzies, Fiona Mhairi ^a   Banks, Rosamonde Elizabeth ^c   Shaw, Pamela Jean ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; NEUROLOGY; PROTEINS; RNA;

CYTOSOLIC PROTEOME;

BIOCHEMISTRY;

12 HYDROXYLEUKOTRIENE B4 DEHYDROGENASE; ANTIOXIDANT; ARGININOSUCCINATE LYASE; ARGININOSUCCINATE SYNTHASE; COPPER ZINC SUPEROXIDE DISMUTASE; ENZYME; GLUTATHIONE TRANSFERASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEROXIREDOXIN; PEROXIREDOXIN I; PROTEASOME; PROTEASOME SUBUNIT BETA 5; PROTEIN; PROTEOME; RNA BINDING MOTIF PROTEIN 3; UNCLASSIFIED DRUG; GLUTATHIONE; PRIMER DNA; RECOMBINANT PROTEIN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANALYTIC METHOD; ANIMAL CELL; ARTICLE; DISEASE ASSOCIATION; ENZYME ACTIVITY; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPINAL CORD MOTONEURON; SYNTHESIS; WESTERN BLOTTING; AMINO ACID SUBSTITUTION; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL CLONE; CELL LINE; CYTOSOL; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; KINETICS; METABOLISM; MOTOR NEURON DISEASE; NUCLEOTIDE SEQUENCE; SITE DIRECTED MUTAGENESIS; TRANSGENIC MOUSE;

ANIMALIA;

AMINO ACID SUBSTITUTION; ANIMALS; BASE SEQUENCE; CELL LINE; CLONE CELLS; CYTOSOL; DNA PRIMERS; GLUTATHIONE; HUMANS; KINETICS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MOTOR NEURON DISEASE; MUTAGENESIS, SITE-DIRECTED; NITRIC OXIDE; PROTEOME; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SUPEROXIDE DISMUTASE; TRANSFECTION;

EID: 0037458659     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209915200     Document Type: Article

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