Nonideality and the nucleation of sickle hemoglobin

Biophysical Journal

Volumn 79, Issue 2, 2000, Pages 1016-1022

  Ivanova, Maria ^a   Jasuja, Ravi ^a   Kwong, Suzanna ^b   Briehl, Robin W ^b   Ferrone, Frank A ^a  

^a DREXEL UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A; HEMOGLOBIN S;

ARTICLE; CROSS LINKING; HEMOGLOBIN ANALYSIS; HYBRID; LIGHT SCATTERING; POLYMERIZATION; THEORY;

EID: 0033876435     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76355-7     Document Type: Article

References (5)

1. Benesch, R., and S. Kwong. 1991. Hemoglobin tetramers stabilized by a single intramolecular cross-link. J. Protein Chem. 10:503-510.
2. Bookchin, R., T. Balazs, Z. Wang, R. Josephs, and V. Lew. 1999. Polymer structure and solubility of deoxyhemoglobin S in the presence of high concentrations of volume-excluding 70-kDa dextran. J. Biol. Chem. 274:6689-6697.
3. Cao, Z., and F. A. Ferrone. 1997. Homogeneous nucleation in sickle hemoglobin. Stochastic measurements with a parallel method. Biophys. J. 72:343-372.
4. Charache, S., M. L. Perrin, R. D. Morre, G. J. Dover, F. B. Barton, S. V. Eckert, R. P. McMahon, and D. R. Bonds. 1995. Effect of hydroxyurea on the frequency of painful crises in sickle cell anemia. N. Engl. J. Med. 332:1317-1322.
5. Chatterjee, R., E. V. Welty, R. Y. Walder, S. L. Pruitt, P. H. Rogers, A. Arnone, and J. A. Walder. 1986. Isolation and characterization of a new hemoglobin derivative cross-linked between the α chains (lysine 99α1-lysine 99α2). J. Biol. Chem. 261:9929-9937.