Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA

Neurobiology of Disease

Volumn 20, Issue 3, 2005, Pages 943-952

  Wang, Jiou ^a   Xu, Guilian ^a   Slunt, Hilda H ^a   Gonzales, Victoria ^a   Coonfield, Michael ^a   Fromholt, David ^a   Copeland, Neal G ^b   Jenkins, Nancy A ^b   Borchelt, David R ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Disease model; FALS; Protein aggregation; Superoxide dismutase; Transgenic mice

Indexed keywords

COMPLEMENTARY DNA; COPPER ZINC SUPEROXIDE DISMUTASE; MUTANT PROTEIN; PRION PROTEIN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASTROCYTE; BRAIN STEM; CELL LINEAGE; GENE EXPRESSION; HOMOZYGOSITY; MACROPHAGE; MOTOR NEURON DISEASE; MOUSE; NERVE CELL; NEUROMUSCULAR SYSTEM; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION; SPINAL CORD; TRANSGENE; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; GENETIC PREDISPOSITION TO DISEASE; HOMOZYGOTE; HUMANS; INCLUSION BODIES; MICE; MICE, TRANSGENIC; MOTOR NEURONS; MUSCLE, SKELETAL; MUTATION; NEUROMUSCULAR JUNCTION; PARALYSIS; SUPEROXIDE DISMUTASE; TRANSGENES;

EID: 26244451092     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.06.005     Document Type: Article

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