Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation

Journal of Biological Chemistry

Volumn 276, Issue 36, 2001, Pages 34156-34161

  Azriel, Ronit ^b   Gazit, Ehud ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; MOLECULAR DYNAMICS; POLYPEPTIDES; TURBIDITY;

AROMATIC RESIDUES;

BIOCHEMISTRY;

AMYLIN; CONGO RED; HEXAPEPTIDE; PHENYLALANINE; ALANINE; AMYLOID; ASPARAGINE; COLORING AGENT; GLYCINE; PEPTIDE;

AMYLOIDOSIS; ANALYTIC METHOD; ARTICLE; ELECTRON MICROSCOPY; GLUCOSE HOMEOSTASIS; LIGHT SCATTERING; NONHUMAN; PANCREAS ISLET BETA CELL; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; STRUCTURE ANALYSIS; TURBIDITY; AMINO ACID SEQUENCE; CHEMICAL MODEL; CHEMISTRY; HUMAN; KINETICS; LIGHT; MOLECULAR GENETICS; PROTEIN BINDING; RADIATION SCATTERING; SEQUENCE HOMOLOGY; TIME;

ALANINE; AMINO ACID SEQUENCE; AMYLOID; ASPARAGINE; COLORING AGENTS; CONGO RED; GLYCINE; HUMANS; KINETICS; LIGHT; MICROSCOPY, ELECTRON; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; PEPTIDES; PHENYLALANINE; PROTEIN BINDING; SCATTERING, RADIATION; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS;

EID: 0035823520     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102883200     Document Type: Article

References (49)

1. Harper, J. D. & Lansbury, P. T., Jr. (1997) Annu. Rev. Biochem. 66, 385-407
2. Prusiner, S. B., Scott, M. R., DeArmond, S. J. & Cohen, F. E. (1998) Cell. 93, 337-348
3. Dobson, C. M. (1999) Trends Biochem. Sci. 24, 329-332
4. Sipe, J. D. & Cohen, A. S. (2000) J. Struct. Biol. 130, 88-98
5. Westermark, P., Wernstedt, C., O'Brien, T. D., Hayden, D. W. & Johnson, K. H. (1987) Am. J. Pathol. 127, 414-417
6. Luskey, K. L. (1992) Diabetes Care 15, 297-299
7. Kahn, S. E., Andrikopoulos, S. & Verchere, C. B. (1999) Diabetes 48, 241-253
8. Höppener, J. W. M., Ahrén, B. & Lips, C. J. M. (2000) N. Engl. J. Med. 343, 411-419
9. Westermark, P., Wernstedt, C., Wilander, E. & Sletten, K. (1986) Biochem. Biophys. Res. Commun. 140, 827-831
10. Clark, A., Cooper, G. J. S., Lewis, C. E., Morris, J. F., Willis, A. C., Reid, K. B. & Turner, R. C. (1987) Lancet 2, 231-234
11. Cooper, G. J. S., Willis, A. C., Clark, A., Turner, R. C., Sim, R. B. & Reid, K. B. M. (1987) Proc. Natl. Acad. Sci., U. S. A. 84, 8628-8632
12. Westermark, P., Wernstedt, C., Wilander, E., Hayden, D. W., O'Brien, T. D. & Johnson, K. H. (1987) Proc. Natl. Acad. Sci., U. S. A. 84, 3881-3885
13. Westermark, P., Engström, U., Johnson, K. H., Westermark, G. T. & Betsholtz, C. (1990) Proc. Natl. Acad. Sci., U. S. A. 87, 5036-5040
14. Sipe, J. D. (1994) Crit. Rev. Clin. Lab. Sci. 31, 325-254
15. Moriarty, D. F. & Raleigh, D. P. (1999) Biochemistry 38, 1811-1818
16. Rink, T. J., Beaumont, K., Koda, J. & Young, A. (1993) Trends Pharmacol. Sci. 14, 113-118
17. Goldsbury, C., Goldie, K., Pellaud, J., Seelig, J., Frey, P., Müller, S. A., Kistler, J., Cooper, G. J. S. & Aebi, U. (2000) J. Struct. Biol. 130, 352-362
18. Lorenzo, A., Razzaboni, B., Weir, G. C. & Yankner, B. A. (1994) Nature 368, 756-760
19. Lorenzo, A. & Yankner, B. A. (1994) Proc. Natl. Acad. Sci., U. S. A. 91, 12243-12247
20. Kapurniotu, A., Bernhagen, J., Greenfield, N., Al-Abed, Y., Teichberg, S., Frank, R. W., Voelter, W. & Bucala, R. (1998) Eur. J. Biochem. 251, 208-216
21. Kayed, R., Bernhagen, J., Greenfield, N., Sweimeh, K., Brunner, H., Voelter, W. & Kapurniotu, A. (1999) J. Mol. Biol. 287, 781-796
22. Larson, J. L., Ko, E. & Miranker, A. D. (2000) Protein Sci. 9, 427-431
23. Ashburn T. T. & Lansbury, P. T., Jr. (1993) J. Am. Chem. Soc. 115, 11012-11013
24. Tenidis, K., Waldner, M., Bernhagen, J., Fischle, W., Bergmann, M., Weber, M., Merkle, M. L., Voelter, W., Brunner, H. & Kapurniotu, A. (2000) J. Mol. Biol. 295, 1055-1071
25. Cohen, A. S., Shirhama, T. & Skinner, M. (1982) in Electron Microscopy of Proteins 3. (Heris, J. R., ed) pp. 165-205, Academic Press, New York
26. Taylor, D. L., Allen, R. D. & Benditt, E. P. (1974) J. Histochem. Cytochem. 22, 1105-1112
27. Cooper, J. H. (1974) Lab. Investig. 31, 232-238
28. Jarrett, J. T. & Lansbury, P. T., Jr. (1992) Biochemistry 31, 12345-12352
29. Lansbury, P. T., Jr. (1992) Biochemistry 31, 6865-6870
30. Richardson, J. S. & Richardson, D. C. (1989) Trends Biochem. Sci. 14, 304-309
31. Wisniewski, T., Ghiso, J. & Frangione, B. (1991) Biochem. Biophys. Res. Commun. 179, 1247-1254
32. Clements, A., Walsh, D. M., Williams, C. H. & Allsop, D. (1993) Neurosci. Lett. 101, 17-20
33. Tjernberg, L. O., Näslund, J., Lindqvist, F., Johansson, J., Karlström, A. R., Thyberg, J., Terenius, L. & Nordstedt, C. (1996) J. Biol. Chem. 271, 8545-8548
34. Findeis, M. A., Musso, G. M., Arico-Muendel, C. C., Benjamin, H. W., Hundal, A. M., Lee, J.-J., Chin, J., Kelley, M., Wakefield, J., Hayward, N. J. & Molineaux, S. M. (1999) Biochemistry 38, 6791-6800
35. Pallitto, M. M., Ghanta, J., Heinzelman, P., Kiessling, L. L. & Murphy, R. M. (1999) Biochemistry 38, 3570-3578
36. Soto, C., Sigurdsson, E. M., Morelli, L., Kumar, R. A., Castano, E. M. & Frangione, B. (1998) Nat. Med. 4, 822-826
37. McGaughey, G. B., Gagné, M. & Rappé, A. K. (1998) J. Biol. Chem. 273, 15458-15463
38. Sun, S. & Bernstein, E. R. (1996) J. Phys. Chem. 100, 13348-13366
39. Hunter, C. A. (1993) Angew. Chem. Int. Ed. Engl. 32, 1584-1586
40. Hunter, C. A. (1994) Chem. Soc. Rev. 23, 101-109
41. Findeis, M. A. (2000) Biochim. Biophys. Acta 1502, 76-84
42. Kuner, P., Bohrmann, B., Tjernberg, L. O., Näslund, J., Huber, G., Celenk, S., Grüninger-Leitch, F., Richards, J. G., Jakob-Rætne, R., Kemp, J. A. & Nordstedt, C. (2000) J. Biol. Chem. 275, 1673-1678
43. Twyman, L. J. & Allsop, D. (1999) Tetrahedron Lett. 40, 9383-9384
44. Häggqvist, B., Näslund, J., Sletten, K., Westermark, G. T., Mucchiano, G., Tjernberg, L. O., Nordstedt, C., Engström, U. & Westermark, P. (1999) Proc. Natl. Acad. Sci., U. S. A. 96, 8669-8674
45. Maury, C. P. & Nurmiaho-Lassila, E. L. (1992) Biochem. Biophys. Res. Commun. 183, 227-231
46. Westermark, G. T., Engström, U. & Westermark, P. (1992) Biochem. Biophys. Res. Commun. 182, 27-33
47. Priola, S. A. & Chesebro, B. (1998) J. Biol. Chem. 273, 11980-11985
48. Patino, M. M., Liu, J. J., Glover, J. R. & Lindquist, S. (1996) Science 273, 622-626
49. Tuite, M. F. (2000) Cell 100, 289-292