Dimer destabilization in superoxide dismutase may result in disease-causing properties: Structures of motor neuron disease mutants

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 16, 2004, Pages 5976-5981

  Hough, Michael A ^a   Grossmann, J Günter ^a   Antonyuk, Svetlana V ^a   Strange, Richard W ^a   Doucette, Peter A ^b   Rodriguez, Jorge A ^b   Whitson, Lisa J ^c   Hart, P John ^c   Hayward, Lawrence J ^d   Valentine, Joan Selverstone ^b   Hasnain, S Samar ^a  

^a DARESBURY LABORATORY   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Crystal structure; Human superoxide dismutase; Neurodegenerative disease; X ray solution scattering

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DIMERIZATION; INFORMATION PROCESSING; MOTOR NEURON DISEASE; PRIORITY JOURNAL; RADIATION SCATTERING; TEMPERATURE; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; MUTATION; SCATTERING, RADIATION; SUPEROXIDE DISMUTASE;

BOVINAE;

EID: 11144357460     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0305143101     Document Type: Article

References (42)

1. Brown, R. H., Jr. (1995) Cell 80, 687-692.
2. Maier, C. M. & Chan, P. K. (2002) Neuroscientist 8, 323-334.
3. Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H. X., et al. (1993) Nature 362, 59-56.
4. Gaudette, M., Hirano, M. & Siddique, T. (2000) Amyotroph. Lateral Scler. 1, 83-89.
5. Cleveland, D. W. & Rothstein, J. D. (2001) Nat. Rev. Neurosci. 11, 806-819.
6. Reaume, A. G., Elliot, J. L., Hoffman, E. K., Kowall, N. W., Ferrante, R. J., Siwek, D. F., Wilcox, H. M., Flood, D. G., Beal, M. F., Brown, R. H., Jr., et al. (1996) Nat. Genet. 13, 43-47.
7. Wong, P. C., Pardo, C. A., Borchelt, D. R., Lee, M. K., Copeland, N. G., Jenkins, N. A., Sisodia, S. S., Cleveland, D. W. & Price, D. L. (1995) Neuron 14, 1105-1116.
8. Jaarsma, D., Haasdijk, E. D., Grashorn, J. A. C., Hawkins, R., van Duijn, W., Verspaget, H. W., London, J. & Holstege, J. C. (2000) Neurobiol. Dis. 7, 623-643.
9. Gurney, M. E., Pu, H., Chiu, A. Y., Dal Canto, M. C., Polchow, C. Y., Alexander, D. D., Caliendo, J., Hentati, A., Kwon, Y. W., Deng, H. X., et al. (1994) Science 264, 1772-1775.
10. Borchelt, D. R., Lee, M. K., Slunt, H. S., Guarnieri, M., Xu, Z. S., Wong, P. C., Brown, R. H., Jr., Price, D. L., Sisodia, S. S. & Cleveland, D. W. (1994) Proc. Natl. Acad. Sci. USA 91, 8292-8296.
11. Fridovich, I. (1975) Annu. Rev. Biochem. 44, 147-159.
12. Tainer, J. A., Getzoff, E. D., Richardson, J. S. & Richardson, D. C. (1983) Nature 306, 284-287.
13. Parge, H. E., Hallewell, R. A. & Tainer, J. A. (1992) Proc. Natl. Acad. Sci. USA 89, 6109-6113.
14. Strange, R. W., Antonyuk, S., Hough, M. A., Doucette, P., Rodriguez, J., Hart, P. J., Hayward, L. J., Valentine, J. S. & Hasnain, S. S. (2003) J. Mol. Biol. 328, 877-891.
15. Cudkowicz, M. E., McKenna-Yasek, D., Chin, W., Geller, B., Hayden, D. L., Schoenfeld, D. A., Hosler, B. A., Horvitz, H. R. & Brown, R. H. (1997) Ann. Neurol. 41, 210-221.
16. Rosen, D. R., Bowling, A. C., Patterson, D., Usdin, T. B., Sapp, P., Mezey E., McKenna-Yasek, D., O'Regan, J., Rahmani, Z., Ferrante, R. J., et al. (1994) Hum. Mol. Genet. 3, 981-987.
17. Kokubo, Y., Kuzuhara, S., Narita, Y., Kikugawa, K.; Nakano R. Inuzuka, T., Tsuji, S., Watanabe, M., Miyazaki, T., Murayama, S. & Ihara, Y. (1999) Arch. Neurol. (Chicago) 56, 1506-1508.
18. Andersen, P. M. (2001) Amyotroph. Lateral Scler. Other Motor Neuron Disord. 2, S37-S41.
19. Hayward, L. J., Rodriguez, J. A., Kim, J. M., Tiwari, A., Goto, J. J., Cabelli, D. D., Valentine, J. S. & Brown, J. H., Jr. (2002). J. Biol. Chem. 277, 15923-15931.
20. Valentine, J. S. & Hart, P. J. (2003) Proc. Natl. Acad. Sci. USA 100, 3617-3622.
21. Rodriguez, J. A., Valentine, O. S., Eggers, D. K., Roe, J. A., Tiwari, A., Brown, R. H. & Hayward, L. J. (2002). J. Biol. Chem. 277, 15932-15937.
22. Tiwari, A. & Hayward, L. J. (2003) J. Biol. Chem. 278, 5984-5992.
23. Takamiya, R., Takahashi, M., Myint, T., Park, Y. S., Miyazawa, N., Endo, T., Fujiwara, N., Sakiyama, H., Misonou, Y., Miyamoto, Y., et al. (2003) FASEB J. 17, U452-U469.
24. Wilson, M. A., Collins, J. L., Hod, Y., Ringe, D. & Petsko, G. A. (2003) Proc. Natl. Acad. Sci. USA 100, 9256-9261.
25. Vagin, A. A. & Teplyakov, A. J. (1997) J. Appl. Crystallogr. 30, 1022-1025.
26. Murshudov, G. N., Vagin, A. A. & Dodson, E. J. (1997) Acta Crystallogr. D 53, 240-255.
27. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. (1991)Acta Crystallogr. A 47, 110-119.
28. Lamzin, V. S. & Wilson, K. S. (1993) Acta Crystallogr. D 49, 129-149.
29. Winn, M. D., Isupov, M. N. & Murshudov, G. N. (2001) Acta Crystallogr. D 57, 122-133.
30. Towns-Andrews, E., Berry, A., Bordas, J., Mant, G. R., Murray, K., Roberts, K., Sumner, I., Worgan, J. S. & Lewis, R. (1989) Rev. Sci. Instrum. 60, 2346-2349.
31. Hasnain, S. S., Murphy, L. M., Strange, R. W., Grossmann, J. G., Clarke, A. R., Jackson, G. S. & Collinge, J. (2001) J. Mol. Biol. 311, 467-473.
32. Semenyuk, A. V. & Svergun, D. I. (1991) J. Appl. Crystallogr. 24, 537-540.
33. Svergun, D. I. (1999) Biophys. J. 76, 2879-2886.
34. Deng, H. X., Hentati, A., Iqbal, Z., Cayabyab, A., Hung, W. Y., Getzoff, E. D., Hu, P., Herzfeldt, B., Rood, R. P., Warner, C., et al. (1993) Science 261, 1047-1051.
35. Elam, J. S., Taylor, A. B., Strange, R., Antonyuk, S. V., Doucette, P. A., Rodriguez, J. A., Hasnain, S. S., Hayward, L. J., Valentine, J. S., Yeates, T. O. & Hart, P. J. (2003) Nat. Struct. Biol. 10, 461-467.
36. Cardoso, R. M. F., Thayer, M. M., DiDonato, M., Lo, T. P., Bruns, C. K., Getzoff, E. D. & Tainer, J. A. (2002) J. Mol. Biol. 324, 247-256.
37. Hand, C. K. & Rouleau, G. A. (2002) Muscle Nerve 25, 135-159.
38. Wiedau-Pazos, M., Goto, J. J., Rabizadeh, S., Gralla, E. B., Roe, J. A., Lee, M. K., Valentine, J. S. & Bredesen, D. E. (1996) Science 271, 515-518.
39. Yim, H. S., Kang, J. H., Chock, P. B., Stadtman, E. R. & Yim, M. B. (1997) J. Biol. Chem. 272, 8861-8863.
40. Valentine, J. S. (2002) Free Radical Biol. Med. 33, 1314-1320.
41. Goto, J. J., Zhu, H. J., Sanchez, R. J., Nersissian, A. M., Gralla, E. D. & Valentine, J. S. (2000) J. Biol. Chem. 275, 1007-1014.
42. Elam, J. S., Malek, K., Rodriguez, J. A., Doucette, P. A., Taylor, A. P., Hayward, L. J., Cabelli, D. E., Valentine, J. S. & Hart. P. J. (2003) J. Biol. Chem. 278, 21032-21039.