Structure, stability, and aggregation of paired helical filaments from tau protein and FTDP-17 mutants probed by tryptophan scanning mutagenesis

Journal of Biological Chemistry

Volumn 277, Issue 44, 2002, Pages 41390-41400

  Li, Li ^a   Von Bergen, Martin ^a   Mandelkow, Eva Maria ^a   Mandelkow, Eckhard ^a  

^a MAX PLANCK UNIT FOR STRUCTURAL MOLECULAR BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; DYES; ENERGY TRANSFER; FLUORESCENCE; MOLECULAR STRUCTURE; MUTAGENESIS; PHOTOPOLYMERIZATION;

MUTANTS;

PROTEINS;

TAU PROTEIN; TRYPTOPHAN;

ALZHEIMER DISEASE; ARTICLE; CONFORMATIONAL TRANSITION; FLUORESCENCE; FRONTOTEMPORAL DEMENTIA; MICROTUBULE ASSEMBLY; PAIRED HELICAL FILAMENT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MOTIF; PROTEIN POLYMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE;

ALZHEIMER DISEASE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MUTAGENESIS; NEUROFIBRILLARY TANGLES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; REPETITIVE SEQUENCES, AMINO ACID; TAU PROTEINS; TRYPTOPHAN;

EID: 0036830506     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M206334200     Document Type: Article

References (54)

1. Cleveland, D. W., Hwo, S. Y., and Kirschner, M. W. (1977) J. Mol. Biol. 116, 227-247
2. Mandelkow, E. M., and Mandelkow, E. (1998) Trends Cell Biol. 8, 425-427
3. Lee, G., Cowan, N., and Kirschner, M. (1988) Science 239, 285-288
4. Goedert, M. (1998) Prog. Brain Res. 117, 287-306
5. Kosik, K., Orecchio, L., Binder, L., Trojanowski, J., Lee, V., and Lee, G. (1988) Neuron 1, 817-825
6. Wischik, C. M., Novak, M., Edwards, P. C., Klug, A., Tichelaar, W., and Crowther, R. A. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 4884-4888
7. Jakes, R., Novak, M., Davison, M., and Wischik, C, M. (1991) EMBO J. 10, 2725-2729
8. Butner, K. A., and Kirschner, M. W. (1991) J. Cell Biol. 115, 717-730
9. Wille, H., Drewes, G., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (1992) J. Cell Biol. 118, 573-584
10. Wilson, D. M., and Binder, L. I. (1995) J. Biol. Chem. 270, 24306-24314
11. DeTure, M. A., Zhang, E. Y., Bubb, M. R., and Purich, D. L. (1996) J. Biol. Chem. 271, 32702-32706
12. Perez, M., Valpuesta, J. M., Medina, M., Montejo de Garcini, E., and Avila, J. (1996) J. Neurochem. 67, 1183-1190
13. Schweers, O., Mandelkow, E. M., Biernat, J., and Mandelkow, E. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 8463-8467
14. Goedert, M., Jakes, R., Spillantini, M. G., Hasegawa, M., Smith, M. J., and Crowther, R. A. (1996) Nature 383, 550-553
15. Kampers, T., Friedhoff, P., Biernat, J., and Mandelkow, E. M. (1996) FEBS Lett. 399, 344-349
16. Friedhoff, P., von Bergen, M., Mandelkow, E. M., Davies, P., and Mandelkow, E. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15712-15717
17. Friedhoff, P., Schneider, A., Mandelkow, E. M., and Mandelkow, E. (1998) Biochemistry 37, 10223-10230
18. King, M. E., Ahuja, V., Binder, L. I., and Kuret, J. (1999) Biochemistry 38, 14851-14859
19. Garzon-Rodriguez, W., Vega, A., Sepulveda-Becerra, M., Milton, S., Johnson, D. A., Yatsimirsky, A. K., and Glabe, C. G. (2000) J. Biol. Chem. 275, 22645-22649
20. Fraser, P. E., McLachlan, D. R., Surewicz, W. K., Mizzen, C. A., Snow, A. D., Nguyen, J. T., and Kirschner, D. A. (1994) J. Mol. Biol. 244, 64-73
21. Biernat, J., Mandelkow, E. M., Schröter, C., Lichtenberg-Kraag, B., Steiner, B., Berling, B., Meyer, H. E., Mercken, M., Vandermeeren, A., Goedert, M., and Mandelkow, E. (1992) EMBO J. 11, 1593-1597
22. Goedert, M., Spillantini, M. G., Jakes, R., Rutherford, D., and Crowther, R. A. (1989) Neuron 3, 519-526
23. Gustke, N., Trinczek, B., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (1994) Biochemistry 33, 9511-9522
24. Barghorn, S., Zheng-Fischhofer, Q., Ackmann, M., Biernat, J., von Bergen, M., and Mandelkow, E. (2000) Biochemistry 39, 11714-11721
25. von Bergen, M., Barghorn, S., Li, L., Marx, A., Biernat, J., Mandelkow, E. M., and Mandelkow, E. (2001) J. Biol. Chem. 276, 48165-48174
26. Schweers, O., Schonbrunn-Hanebeck, E., Marx, A., and Mandelkow, E. (1994) J. Biol. Chem. 269, 24290-24297
27. von Bergen, M., Friedhoff, P., Biernat, J., Heberle, J., Mandelkow, E. M., and Mandelkow, E. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 5129-5134
28. Ksiezak-Reding, H., and Yen, S. H. (1991) Neuron 6, 717-728
29. Rapoport, M., Dawson, H. N., Binder, L. I., Vitek, M. P., and Ferreira, A. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 6364-6369
30. Gasymov, O. K., Abduragimov, A. R., Yusifov, T. N., and Glasgow, B. J. (2001) Biochemistry 40, 14754-14762
31. Ropson, I. J., and Dalessio, P. M. (1997) Biochemistry 36, 8594-8601
32. Rizzu, P., Van Swieten, J. C., Joosse, M., Hasegawa, M., Stevens, M., Tibben, A., Niermeijer, M. F., Hillebrand, M., Ravid, R., Oostra, B. A., Goedert, M., van Duijn, C. M., and Heutink, P. (1999) Am. J. Hum. Genet. 64, 414-421
33. Byler, D. M., and Susi, H. (1986) Biopolymers 25, 469-487
34. Susi, H., and Byler, D. M. (1983) Biochem. Biophys. Res. Commun. 115, 391-397
35. Goode, B. L., and Feinstein, S. C, (1994) J. Cell Biol. 124, 769-782
36. Carmel, G., Mager, E. M., Binder, L. I., and Kuret, J. (1996) J. Biol. Chem. 271, 32789-32795
37. Jicha, G. A., Bowser, R., Kazam, I. G., and Davies, P. (1997) J. Neurosci. Res. 48, 128-132
38. Lichtenberg-Kraag, B., Mandelkow, E. M., Biernat, J., Steiner, B., Schroter, C., Gustke, N., Meyer, H. E., and Mandelkow, E. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5384-5388
39. Abraha, A., Ghoshal, N., Gamblin, T. C., Cryns, V., Berry, R. W., Kuret, J., and Binder, L. I. (2000) J. Cell Sci. 113, 3737-3745
40. Chiu, H. C., and Bersohn, R. (1977) Biopolymers 16, 277-288
41. Eisinger, J. (1969) Biochemistry 8, 3902-3908
42. Wilson, D. M., and Binder, L. I. (1997) Am. J. Pathol. 150, 2181-2195
43. Goedert, M., Jakes, R., and Crowther, R. A. (1999) FEBS Lett. 450, 306-311
44. Gamblin, T. C., King, M. E., Dawson, H., Vitek, M. P., Kuret, J., Berry, R. W., and Binder, L. I. (2000) Biochemistry. 39, 6136-6144
45. Lansbury, P. J. (1997) Neuron 19, 1151-1154
46. Pike, C. J., Walencewicz-Wasserman, A. J., Kosmoski, J., Cribbs, D. H., Glabe, C. G., and Cotman, C. W. (1995) J. Neurochem. 64, 253-265
47. Kirschner, D. A., Inouye, H., Duffy, L. K., Sinclair, A., Lind, M., and Selkoe, D. J. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6953-6957
48. Hyman, B. T., Smith, C., Buldyrev, I., Whelan, C., Brown, H., Tang, M. X., and Mayeux, R. (2001) Ann. Neurol. 49, 808-810
49. Takano, K., Funahashi, J., and Yutani, K. (2001) Eur. J. Biochem. 268, 155-159
50. Perry, G., Siedlak, S. L., Richey, P., Kawai, M., Cras, P., Kalaria, R. N., Galloway, P. G., Scardina, J. M., Cordell, B., and Greenberg, B. D. (1991) J. Neurosci. 11, 3679-3683
51. Ledesma, M. D., Bonay, P., Colaco, C., and Avila, J. (1994) J. Biol. Chem. 269, 21614-21619
52. Johnson, G. V. W., and Hartigan, J. A. (1998) Alzheimer's Dis. Rev. 3, 125-141
53. Hong, M., Zhukareva, V., Vogelsberg-Ragaglia, V., Wszolek, Z., Reed, L., Miller, B. I., Geschwind, D. H., Bird, T. D., McKeel, D., Goate, A., Morris, J. C., Wilhelmsen, K. C., Schellenberg, G. D., Trojanowski, J. Q., and Lee, V. M. (1998) Science 282, 1914-1917
54. Goedert, M., Spillantini, M. G., Potier, M. C., Ulrich, J., and Crowther, R. A. (1989) EMBO J. 8, 393-399