Functional reconstitution of γ-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2

Journal of Neuroscience Research

Volumn 77, Issue 3, 2004, Pages 309-322

  Periz, Goran ^a   Fortini, Mark E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

secretase; Alzheimer's disease; APP; Notch; Signal transduction

Indexed keywords

ASPARTIC PROTEINASE; CELL SURFACE RECEPTOR; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ANIMAL CELL; ENZYME ACTIVE SITE; ENZYME RECONSTITUTION; HYDROPHOBICITY; LIPID BILAYER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; ENDOPEPTIDASES; HUMANS; MACROMOLECULAR SUBSTANCES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PRESENILIN-1;

EID: 3242811966     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20203     Document Type: Review

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