Different cofactor activities in γ-secretase assembly: Evidence for a nicastrin - Aph-1 subcomplex

Journal of Cell Biology

Volumn 161, Issue 4, 2003, Pages 685-690

  Hu, Yue ^a   Fortini, Mark E ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Amyloid; Drosophila; Notch; Pen 2; Presenilin

Indexed keywords

ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; GAMMA SECRETASE; MEMBRANE PROTEIN; NICASTRIN; NOTCH RECEPTOR; PRESENILIN 1; PROTEIN PEN 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENDOPEPTIDASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; MACROMOLECULAR SUBSTANCES; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MUTATION; PRESENILIN-1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0038360879     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200304014     Document Type: Article

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