The Intracellular Domain of the β-Amyloid Precursor Protein Is Stabilized by Fe65 and Translocates to the Nucleus in a Notch-like Manner

Journal of Biological Chemistry

Volumn 276, Issue 43, 2001, Pages 40288-40292

  Kimberly, W Taylor ^b   Zheng, Jessica B ^b   Guénette, Suzanne Y ^b   Selkoe, Dennis J ^a  

^a HARVARD INSTITUTES OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; PROTEINS;

TRANSCRIPTION;

BIOCHEMISTRY;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; MEMBRANE PROTEIN; METALLOPROTEINASE; NOTCH RECEPTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; ADAM PROTEIN; APBB1 PROTEIN, HUMAN; ASPARTIC PROTEINASE; BACE1 PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DROSOPHILA PROTEIN; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE FRAGMENT; PROTEINASE; REPRESSOR PROTEIN; SECRETASE; SUPPRESSOR OF HAIRLESS PROTEIN, DROSOPHILA; TRANSACTIVATOR PROTEIN; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; GENETIC TRANSCRIPTION; LIGAND BINDING; NERVE CELL; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SEQUENCE ANALYSIS; SIGNAL PROCESSING; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; HALF LIFE TIME; METABOLISM; PROTEIN BINDING; PROTEIN PROCESSING;

ANIMALIA;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAM PROTEINS; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; CREB-BINDING PROTEIN; DROSOPHILA PROTEINS; ENDOPEPTIDASES; HALF-LIFE; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, NOTCH; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 0035955693     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C100447200     Document Type: Article

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