Activated Notch1 associates with a presenilin-1/γ-secretase docking site

Journal of Neurochemistry

Volumn 87, Issue 4, 2003, Pages 843-850

  Ramdya, Pavan ^a   Skoch, Jesse ^a   Bacskai, Brian J ^a   Hyman, Bradley T ^a   Berezovska, Oksana ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

secretase inhibitor; Docking site; Fluorescence lifetime imaging microscopy assay; Fluorescence resonance energy transfer; Notch1; Presenilin 1

Indexed keywords

GAMMA SECRETASE; NOTCH RECEPTOR; PRESENILIN 1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL SURFACE; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CELL MEMBRANE; CELLS, CULTURED; CRICETINAE; ENDOPEPTIDASES; ENZYME INHIBITORS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMANS; LIGANDS; MACROMOLECULAR SUBSTANCES; MEMBRANE PROTEINS; MICE; NEURONS; PRESENILIN-1; PROTEIN BINDING; RECEPTOR, NOTCH1; RECEPTORS, CELL SURFACE; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0344824698     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02030.x     Document Type: Article

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