The biological and pathological function of the presenilin-1 Δexon 9 mutation is independent of its defect to undergo proteolytic processing

Journal of Biological Chemistry

Volumn 274, Issue 12, 1999, Pages 7615-7618

  Steiner, Harald ^a   Romig, Helmut ^b   Grim, Melissa G ^c   Philipp, Uwe ^b   Pesold, Brigitte ^a   Citron, Martin ^d   Baumeister, Ralf ^c   Haass, Christian ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^c Genzentrum   (Germany)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PRESENILIN 1;

ALZHEIMER DISEASE; ARTICLE; CELL LINE; EXON; GENE MUTATION; GENE OVEREXPRESSION; KNOCKOUT GENE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; RNA SPLICING; SITE DIRECTED MUTAGENESIS;

ALZHEIMER DISEASE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINE; EXONS; HUMANS; MEMBRANE PROTEINS; POINT MUTATION; PRESENILIN-1; PROTEIN PROCESSING, POST-TRANSLATIONAL; RNA SPLICING;

EID: 0033583047     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.12.7615     Document Type: Article

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