Co-expressed presenilin 1 NTF and CTF form functional γ-secretase complexes in cells devoid of full-length protein

Journal of Neurochemistry

Volumn 89, Issue 1, 2004, Pages 44-53

  Laudon, Hanna ^a   Mathews, Paul M ^b   Karlström, Helena ^a   Bergman, Anna ^a   Farmery, Mark R ^a   Nixon, Ralph A ^b   Winblad, Bengt ^a   Gandy, Samuel E ^c   Lendahl, Urban ^a   Lundkvist, Johan ^a   Näslund, Jan ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

AICD; Alzheimer's disease; Amyloid peptide; Endoproteolysis; Nicastrin; Presenilin; secretase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ASPARTIC ACID; GAMMA SECRETASE; MEMBRANE PROTEIN; MUTANT PROTEIN; NICASTRIN; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

ANIMALIA; MAMMALIA;

EID: 12144290191     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.02298.x     Document Type: Article

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