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Volumn 275, Issue 52, 2000, Pages 40925-40932

A loss of function mutant of the presenilin homologue SEL-12 undergoes aberrant endoproteolysis in Caenorhabditis elegans and increases Aβ42 generation in human cells

(9) Okochi, Masayasu a Eimer, Stefan a Böttcher, Andreas a Baumeister, Ralf a,c Romig, Helmut b Walter, Jochen a Capell, Anja a Steiner, Harald a Haass, Christian a

a UNIVERSITY OF MUNICH (Germany)

b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG (Germany)

c Genzentrum (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GENE PRODUCT; MUTANT PROTEIN; NOTCH RECEPTOR; PRESENILIN 1; PROTEIN SEL 12; UNCLASSIFIED DRUG;

ALLELE; ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; SEQUENCE HOMOLOGY;

AMYLOID BETA-PROTEIN; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CASPASES; CELL LINE; HELMINTH PROTEINS; HUMANS; MEMBRANE PROTEINS; MUTATION; RECEPTORS, NOTCH;

CAENORHABDITIS ELEGANS;

EID: 0034731432 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M005254200 Document Type: Article

Times cited : (36)

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