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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 10, 2002, Pages 7102-7107

The γ-secretase-generated intracellular domain of β-amyloid precursor protein binds Numb and inhibits Notch signaling

(9) Roncarati, Roberta a Šestan, Nenad b Scheinfeld, Meir H a Berechid, Bridget E b Lopez, Peter A c Meucci, Olimpia d McGlade, Jane C e Rakic, Pasko b D'Adamio, Luciano a

a ALBERT EINSTEIN COLLEGE OF MEDICINE (United States)

b YALE UNIVERSITY SCHOOL OF MEDICINE (United States)

c ROCKEFELLER UNIVERSITY (United States)

d DREXEL UNIVERSITY COLLEGE OF MEDICINE (United States)

e UNIVERSITY OF TORONTO (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GAMMA SECRETASE; NOTCH RECEPTOR; PEPTIDE; PRESENILIN 1; PROTEIN PRECURSOR;

ALZHEIMER DISEASE; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CELL LYSATE; CELL NUCLEUS; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BINDING SITES; CELL LINE, TRANSFORMED; CELLS, CULTURED; ENDOPEPTIDASES; HELA CELLS; HUMANS; INTRACELLULAR FLUID; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, NOTCH; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 0037076398 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.102192599 Document Type: Article

Times cited : (187)

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