PEN-2 is an integral component of the γ-secretase complex required for coordinated expression of presenilin and nicastrin

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39062-39065

  Steiner, Harald ^a   Winkler, Edith ^a   Edbauer, Dieter ^a   Prokop, Stefan ^a   Basset, Gabriele ^a   Yamasaki, Aya ^a   Kostka, Marcus ^b   Haass, Christian ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; ENZYMES; MOLECULAR WEIGHT; RNA;

INTERFERENCE-MEDIATED DOWN-REGULATION;

BIOCHEMISTRY;

ASPARTIC PROTEINASE; GAMMA SECRETASE; NICASTRIN; PRESENILIN 1; PRESENILIN 2; PROTEIN PEN 2; RNA; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELL LINE; DNA, COMPLEMENTARY; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; EPITOPES; HUMANS; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; PRECIPITIN TESTS; PRESENILIN-1; PRESENILIN-2; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA;

ANIMALIA;

EID: 0037131218     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C200469200     Document Type: Article

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