-
1
-
-
0024299087
-
The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
-
Hashimoto C, Hudson KL, Anderson KV: The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 1988;52:269-279.
-
(1988)
Cell
, vol.52
, pp. 269-279
-
-
Hashimoto, C.1
Hudson, K.L.2
Anderson, K.V.3
-
2
-
-
0021603716
-
Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA
-
Anderson KV, Nusslein-Volhard C: Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 1984;311:223-227.
-
(1984)
Nature
, vol.311
, pp. 223-227
-
-
Anderson, K.V.1
Nusslein-Volhard, C.2
-
3
-
-
0022189558
-
Establishment of dorsal-ventral polarity in the Drosophila embryo: The induction of polarity by the Toll gene product
-
Anderson KV, Bokla L, Nusslein-Volhard C: Establishment of dorsal-ventral polarity in the Drosophila embryo: The induction of polarity by the Toll gene product. Cell 1985;42:791-798.
-
(1985)
Cell
, vol.42
, pp. 791-798
-
-
Anderson, K.V.1
Bokla, L.2
Nusslein-Volhard, C.3
-
4
-
-
0029730738
-
A conserved signaling pathway: The Drosophila toll-dorsal pathway
-
Belvin MP, Anderson KV: A conserved signaling pathway: The Drosophila toll-dorsal pathway. Annu Rev Cell Dev Biol 1996;12:393-416.
-
(1996)
Annu Rev Cell Dev Biol
, vol.12
, pp. 393-416
-
-
Belvin, M.P.1
Anderson, K.V.2
-
5
-
-
0026030444
-
Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity
-
Letsou A, Alexander S, Orth K, Wasserman SA: Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity. Proc Natl Acad Sci USA 1991;88:810-814.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 810-814
-
-
Letsou, A.1
Alexander, S.2
Orth, K.3
Wasserman, S.A.4
-
6
-
-
0027499132
-
Pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo
-
Shelton CA, Wasserman SA: Pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo. Cell 1993;72:515-525.
-
(1993)
Cell
, vol.72
, pp. 515-525
-
-
Shelton, C.A.1
Wasserman, S.A.2
-
7
-
-
0033533382
-
Formation and biochemical characterization of tube/pelle death domain complexes: Critical regulators of postreceptor signaling by the Drosophila toll receptor
-
Schiffmann DA, White JH, Cooper A, Nutley MA, Harding SE, Jumel K, Solari R, Ray KP, Gay NJ: Formation and biochemical characterization of tube/pelle death domain complexes: Critical regulators of postreceptor signaling by the Drosophila toll receptor. Biochemistry 1999;38:11722-11733.
-
(1999)
Biochemistry
, vol.38
, pp. 11722-11733
-
-
Schiffmann, D.A.1
White, J.H.2
Cooper, A.3
Nutley, M.A.4
Harding, S.E.5
Jumel, K.6
Solari, R.7
Ray, K.P.8
Gay, N.J.9
-
8
-
-
0033601077
-
Three-dimensional structure of a complex between the death domains of Pelle and Tube
-
Xiao T, Towb P, Wasserman SA, Sprang SR: Three-dimensional structure of a complex between the death domains of Pelle and Tube. Cell 1999;99:545-555.
-
(1999)
Cell
, vol.99
, pp. 545-555
-
-
Xiao, T.1
Towb, P.2
Wasserman, S.A.3
Sprang, S.R.4
-
9
-
-
0026491071
-
Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins
-
Kidd S: Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins. Cell 1992;71:623-635.
-
(1992)
Cell
, vol.71
, pp. 623-635
-
-
Kidd, S.1
-
10
-
-
0031446642
-
Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B, Reichhart JM, Hoffmann JA: Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci USA 1997;94:14614-14619.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B.1
Reichhart, J.M.2
Hoffmann, J.A.3
-
11
-
-
0027220975
-
Kappa B-like motifs regulate the induction of immune genes in Drosophila
-
Engstrom Y, Kadalayil L, Sun SC, Samakovlis C, Hultmark D, Faye I: Kappa B-like motifs regulate the induction of immune genes in Drosophila. J Mol Biol 1993;232:327-333.
-
(1993)
J Mol Biol
, vol.232
, pp. 327-333
-
-
Engstrom, Y.1
Kadalayil, L.2
Sun, S.C.3
Samakovlis, C.4
Hultmark, D.5
Faye, I.6
-
12
-
-
0028877993
-
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila
-
Lemaitre B, Meister M, Govind S, Georgel P, Steward R, Reichhart JM, Hoffmann JA: Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J 1995;14:536-545.
-
(1995)
EMBO J
, vol.14
, pp. 536-545
-
-
Lemaitre, B.1
Meister, M.2
Govind, S.3
Georgel, P.4
Steward, R.5
Reichhart, J.M.6
Hoffmann, J.A.7
-
13
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA: The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996;86:973-983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
14
-
-
0035940499
-
Drosophila MyD88 is an adapter in the Toll signaling pathway
-
Horng T, Medzhitov R: Drosophila MyD88 is an adapter in the Toll signaling pathway. Proc Natl Acad Sci USA 2001;98:12654-12658.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12654-12658
-
-
Horng, T.1
Medzhitov, R.2
-
15
-
-
0027443688
-
Dif, a dorsal-related gene that mediates an immune response in Drosophila
-
Ip YT, Reach M, Engstrom Y, Kadalayil L, Cai H, Gonzalez-Crespo S, Tatei K, Levine M: Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell 1993;75:753-763.
-
(1993)
Cell
, vol.75
, pp. 753-763
-
-
Ip, Y.T.1
Reach, M.2
Engstrom, Y.3
Kadalayil, L.4
Cai, H.5
Gonzalez-Crespo, S.6
Tatei, K.7
Levine, M.8
-
16
-
-
0033711445
-
The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila
-
Rutschmann S, Jung AC, Hetru C, Reichhart JM, Hoffmann JA, Ferrandon D: The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila. Immunity 2000;12:569-580.
-
(2000)
Immunity
, vol.12
, pp. 569-580
-
-
Rutschmann, S.1
Jung, A.C.2
Hetru, C.3
Reichhart, J.M.4
Hoffmann, J.A.5
Ferrandon, D.6
-
17
-
-
0033118490
-
Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor
-
Meng X, Khanuja BS, Ip YT: Toll receptor-mediated Drosophila immune response requires Dif, an NF-kappaB factor. Genes Dev 1999;13:792-797.
-
(1999)
Genes Dev
, vol.13
, pp. 792-797
-
-
Meng, X.1
Khanuja, B.S.2
Ip, Y.T.3
-
18
-
-
0037025213
-
Activation of Drosophila Toll during fungal infection by a blood serine protease
-
Ligoxygakis P, Pelte N, Hoffmann JA, Reichhart JM: Activation of Drosophila Toll during fungal infection by a blood serine protease. Science 2002;297:114-116.
-
(2002)
Science
, vol.297
, pp. 114-116
-
-
Ligoxygakis, P.1
Pelte, N.2
Hoffmann, J.A.3
Reichhart, J.M.4
-
19
-
-
0034610370
-
A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
-
Werner T, Liu G, Kang D, Ekengren S, Steiner H, Hultmark D: A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster. Proc Natl Acad Sci USA 2000;97:13772-13777.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13772-13777
-
-
Werner, T.1
Liu, G.2
Kang, D.3
Ekengren, S.4
Steiner, H.5
Hultmark, D.6
-
20
-
-
0029884417
-
Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori
-
Yoshida H, Kinoshita K, Ashida M: Purification of a peptidoglycan recognition protein from hemolymph of the silkworm, Bombyx mori. J Biol Chem 1996;271:13854-13860.
-
(1996)
J Biol Chem
, vol.271
, pp. 13854-13860
-
-
Yoshida, H.1
Kinoshita, K.2
Ashida, M.3
-
21
-
-
0035856990
-
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
-
Michel T, Reichhart JM, Hoffmann JA, Royet J: Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 2001;414:756-759.
-
(2001)
Nature
, vol.414
, pp. 756-759
-
-
Michel, T.1
Reichhart, J.M.2
Hoffmann, J.A.3
Royet, J.4
-
22
-
-
0034641738
-
Toll-related receptors and the control of antimicrobial peptide expression in Drosophila
-
Tauszig S, Jouanguy E, Hoffmann JA, Imler JL: Toll-related receptors and the control of antimicrobial peptide expression in Drosophila. Proc Natl Acad Sci USA 2000;97:10520-10525.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10520-10525
-
-
Tauszig, S.1
Jouanguy, E.2
Hoffmann, J.A.3
Imler, J.L.4
-
23
-
-
0030663332
-
The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense
-
Williams MJ, Rodriguez A, Kimbrell DA, Eldon ED: The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J 1997;16:6120-6130.
-
(1997)
EMBO J
, vol.16
, pp. 6120-6130
-
-
Williams, M.J.1
Rodriguez, A.2
Kimbrell, D.A.3
Eldon, E.D.4
-
24
-
-
0028326047
-
The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll
-
Eldon E, Kooyer S, D'Evelyn D, Duman M, Lawinger P, Botas J, Bellen H: The Drosophila 18 wheeler is required for morphogenesis and has striking similarities to Toll. Development 1994;120:885-899.
-
(1994)
Development
, vol.120
, pp. 885-899
-
-
Eldon, E.1
Kooyer, S.2
D'Evelyn, D.3
Duman, M.4
Lawinger, P.5
Botas, J.6
Bellen, H.7
-
25
-
-
0036023960
-
Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila
-
Ligoxygakis P, Bulet P, Reichhart JM: Critical evaluation of the role of the Toll-like receptor 18-Wheeler in the host defense of Drosophila. EMBO Rep 2002;3:666-673.
-
(2002)
EMBO Rep
, vol.3
, pp. 666-673
-
-
Ligoxygakis, P.1
Bulet, P.2
Reichhart, J.M.3
-
26
-
-
0028865526
-
A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense
-
Lemaitre B, Kromer-Metzger E, Michaut L, Nicolas E, Meister M, Georgel P, Reichhart JM, Hoffmann JA: A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense. Proc Natl Acad Sci USA 1995;92:9465-9469.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9465-9469
-
-
Lemaitre, B.1
Kromer-Metzger, E.2
Michaut, L.3
Nicolas, E.4
Meister, M.5
Georgel, P.6
Reichhart, J.M.7
Hoffmann, J.A.8
-
27
-
-
0037061450
-
The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein
-
Gottar M, Gobert V, Michel T, Belvin M, Duyk G, Hoffmann JA, Ferrandon D, Royet J: The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 2002;416:640-644.
-
(2002)
Nature
, vol.416
, pp. 640-644
-
-
Gottar, M.1
Gobert, V.2
Michel, T.3
Belvin, M.4
Duyk, G.5
Hoffmann, J.A.6
Ferrandon, D.7
Royet, J.8
-
28
-
-
0037066464
-
Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila
-
Choe KM, Werner T, Stoven S, Hultmark D, Anderson KV: Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila. Science 2002;296:359-362.
-
(2002)
Science
, vol.296
, pp. 359-362
-
-
Choe, K.M.1
Werner, T.2
Stoven, S.3
Hultmark, D.4
Anderson, K.V.5
-
29
-
-
0037061482
-
Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
-
Ramet M, Manfruelli P, Pearson A, Mathey-Prevot B, Ezekowitz RA: Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 2002;416:644-648.
-
(2002)
Nature
, vol.416
, pp. 644-648
-
-
Ramet, M.1
Manfruelli, P.2
Pearson, A.3
Mathey-Prevot, B.4
Ezekowitz, R.A.5
-
30
-
-
18044400563
-
Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis
-
Georgel P, Naitza S, Kappler C, Ferrandon D, Zachary D, Swimmer C, Kopczynski C, Duyk G, Reichhart JM, Hoffmann JA: Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis. Dev Cell 2001;1:503-514.
-
(2001)
Dev Cell
, vol.1
, pp. 503-514
-
-
Georgel, P.1
Naitza, S.2
Kappler, C.3
Ferrandon, D.4
Zachary, D.5
Swimmer, C.6
Kopczynski, C.7
Duyk, G.8
Reichhart, J.M.9
Hoffmann, J.A.10
-
31
-
-
0036850985
-
The Drosophila immune defense against gram-negative infection requires the death protein dFADD
-
Naitza S, Rosse C, Kappler C, Georgel P, Belvin M, Gubb D, Camonis J, Hoffmann JA, Reichhart JM: The Drosophila immune defense against gram-negative infection requires the death protein dFADD. Immunity 2002;17:575-581.
-
(2002)
Immunity
, vol.17
, pp. 575-581
-
-
Naitza, S.1
Rosse, C.2
Kappler, C.3
Georgel, P.4
Belvin, M.5
Gubb, D.6
Camonis, J.7
Hoffmann, J.A.8
Reichhart, J.M.9
-
32
-
-
0034305744
-
The Drosophila caspase Dredd is required to resist gram-negative bacterial infection
-
Leulier F, Rodriguez A, Khush RS, Abrams JM, Lemaitre B: The Drosophila caspase Dredd is required to resist gram-negative bacterial infection. EMBO Rep 2000;1:353-358.
-
(2000)
EMBO Rep
, vol.1
, pp. 353-358
-
-
Leulier, F.1
Rodriguez, A.2
Khush, R.S.3
Abrams, J.M.4
Lemaitre, B.5
-
33
-
-
0032530359
-
Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila
-
Chen P, Rodriguez A, Erskine R, Thach T, Abrams JM: Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila. Dev Biol 1998;201:202-216.
-
(1998)
Dev Biol
, vol.201
, pp. 202-216
-
-
Chen, P.1
Rodriguez, A.2
Erskine, R.3
Thach, T.4
Abrams, J.M.5
-
34
-
-
0035423794
-
Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses
-
Vidal S, Khush RS, Leulier F, Tzou P, Nakamura M, Lemaitre B: Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responses. Genes Dev 2001;15:1900-1912.
-
(2001)
Genes Dev
, vol.15
, pp. 1900-1912
-
-
Vidal, S.1
Khush, R.S.2
Leulier, F.3
Tzou, P.4
Nakamura, M.5
Lemaitre, B.6
-
35
-
-
0035060798
-
The role of the Drosophila TAK homologue dTAK during development
-
Mihaly J, Kockel L, Gaengel K, Weber U, Bohmann D, Mlodzik M: The role of the Drosophila TAK homologue dTAK during development. Mech Dev 2001;102:67-79.
-
(2001)
Mech Dev
, vol.102
, pp. 67-79
-
-
Mihaly, J.1
Kockel, L.2
Gaengel, K.3
Weber, U.4
Bohmann, D.5
Mlodzik, M.6
-
36
-
-
0034287444
-
A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity
-
Silverman N, Zhou R, Stoven S, Pandey N, Hultmark D, Maniatis T: A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes Dev 2000;14:2461-2471.
-
(2000)
Genes Dev
, vol.14
, pp. 2461-2471
-
-
Silverman, N.1
Zhou, R.2
Stoven, S.3
Pandey, N.4
Hultmark, D.5
Maniatis, T.6
-
37
-
-
0035187882
-
The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase
-
Lu Y, Wu LP, Anderson KV: The antibacterial arm of the drosophila innate immune response requires an IkappaB kinase. Genes Dev 2001;15:104-110.
-
(2001)
Genes Dev
, vol.15
, pp. 104-110
-
-
Lu, Y.1
Wu, L.P.2
Anderson, K.V.3
-
38
-
-
0034303573
-
Role of Drosophila IKK gamma in a toll-independent antibacterial immune response
-
Rutschmann S, Jung AC, Zhou R, Silverman N, Hoffmann JA, Ferrandon D: Role of Drosophila IKK gamma in a toll-independent antibacterial immune response. Nat Immunol 2000;1:342-347.
-
(2000)
Nat Immunol
, vol.1
, pp. 342-347
-
-
Rutschmann, S.1
Jung, A.C.2
Zhou, R.3
Silverman, N.4
Hoffmann, J.A.5
Ferrandon, D.6
-
39
-
-
0034303480
-
Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage
-
Stoven S, Ando I, Kadalayil L, Engstrom Y, Hultmark D: Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage. EMBO Rep 2000;1:347-352.
-
(2000)
EMBO Rep
, vol.1
, pp. 347-352
-
-
Stoven, S.1
Ando, I.2
Kadalayil, L.3
Engstrom, Y.4
Hultmark, D.5
-
40
-
-
0025774776
-
Drosophila Toll and IL-1 receptor
-
Gay NJ, Keith FJ: Drosophila Toll and IL-1 receptor (letter). Nature 1991;351:355-356
-
(1991)
Nature
, vol.351
, pp. 355-356
-
-
Gay, N.J.1
Keith, F.J.2
-
41
-
-
0034304668
-
The Toll/interleukin-1 receptor domain: A molecular switch for inflammation and host defence
-
O'Neill L: The Toll/interleukin-1 receptor domain: A molecular switch for inflammation and host defence. Biochem Soc Trans 2000;28:557-563.
-
(2000)
Biochem Soc Trans
, vol.28
, pp. 557-563
-
-
O'Neill, L.1
-
42
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche H, Henzel WJ, Shillinglaw W, Li S, Cao Z: MyD88:an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 1997;7:837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
43
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio M, Ni J, Feng P, Dixit VM: IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 1997;278:1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
44
-
-
0036167107
-
Drosophila innate immunity: An evolutionary perspective
-
Hoffmann JA, Reichhart JM: Drosophila innate immunity: An evolutionary perspective. Nat Immunol 2002;3:121-126.
-
(2002)
Nat Immunol
, vol.3
, pp. 121-126
-
-
Hoffmann, J.A.1
Reichhart, J.M.2
-
45
-
-
0018841829
-
Genetic control of susceptibility to Salmonella typhimurium in mice: Role of the LPS gene
-
O'Brien AD, Rosenstreich DL, Scher I, Campbell GH, MacDermott RP, Formal SB: Genetic control of susceptibility to Salmonella typhimurium in mice: Role of the LPS gene. J Immunol 1980;124:20-24.
-
(1980)
J Immunol
, vol.124
, pp. 20-24
-
-
O'Brien, A.D.1
Rosenstreich, D.L.2
Scher, I.3
Campbell, G.H.4
MacDermott, R.P.5
Formal, S.B.6
-
46
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Huffel CV, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B: Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 1998;282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Huffel, C.V.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
47
-
-
0345561540
-
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
-
Qureshi ST, Lariviere L, Leveque G, Clermont S, Moore KJ, Gros P, Malo D: Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4). J Exp Med 1999;189:615-625.
-
(1999)
J Exp Med
, vol.189
, pp. 615-625
-
-
Qureshi, S.T.1
Lariviere, L.2
Leveque, G.3
Clermont, S.4
Moore, K.J.5
Gros, P.6
Malo, D.7
-
48
-
-
0033120081
-
Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
-
Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S: Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product. J Immunol 1999;162:3749-3752.
-
(1999)
J Immunol
, vol.162
, pp. 3749-3752
-
-
Hoshino, K.1
Takeuchi, O.2
Kawai, T.3
Sanjo, H.4
Ogawa, T.5
Takeda, Y.6
Takeda, K.7
Akira, S.8
-
49
-
-
0031774181
-
Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide
-
Kirschning CJ, Wesche H, Merrill AT, Rothe M: Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 1998;188:2091-2097.
-
(1998)
J Exp Med
, vol.188
, pp. 2091-2097
-
-
Kirschning, C.J.1
Wesche, H.2
Merrill, A.T.3
Rothe, M.4
-
50
-
-
0032541661
-
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
-
Yang RB, Mark MR, Gray A, Huang A, Xie MH, Zhang M, Goddard A, Wood WI, Gurney AL, Godowski PJ: Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 1998;395:284-288.
-
(1998)
Nature
, vol.395
, pp. 284-288
-
-
Yang, R.B.1
Mark, M.R.2
Gray, A.3
Huang, A.4
Xie, M.H.5
Zhang, M.6
Goddard, A.7
Wood, W.I.8
Gurney, A.L.9
Godowski, P.J.10
-
51
-
-
0033564325
-
Cutting edge: Cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin
-
Heine H, Kirschning CJ, Lien E, Monks BG, Rothe M, Golenbock DT: Cutting edge: Cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin. J Immunol 1999;162:6971-6975.
-
(1999)
J Immunol
, vol.162
, pp. 6971-6975
-
-
Heine, H.1
Kirschning, C.J.2
Lien, E.3
Monks, B.G.4
Rothe, M.5
Golenbock, D.T.6
-
52
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
-
Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S: Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 1999;11:443-451.
-
(1999)
Immunity
, vol.11
, pp. 443-451
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
53
-
-
0033168728
-
Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
-
Yoshimura A, Lien E, Ingalls RR, Tuomanen E, Dziarski R, Golenbock D: Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2. J Immunol 1999;163:1-5.
-
(1999)
J Immunol
, vol.163
, pp. 1-5
-
-
Yoshimura, A.1
Lien, E.2
Ingalls, R.R.3
Tuomanen, E.4
Dziarski, R.5
Golenbock, D.6
-
54
-
-
0033585011
-
Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products
-
Lien E, Sellati TJ, Yoshimura A, Flo TH, Rawadi G, Finberg RW, Carroll JD, Espevik T, Ingalls RR, Radolf JD, Golenbock DT: Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products. J Biol Chem 1999;274:33419-33425.
-
(1999)
J Biol Chem
, vol.274
, pp. 33419-33425
-
-
Lien, E.1
Sellati, T.J.2
Yoshimura, A.3
Flo, T.H.4
Rawadi, G.5
Finberg, R.W.6
Carroll, J.D.7
Espevik, T.8
Ingalls, R.R.9
Radolf, J.D.10
Golenbock, D.T.11
-
55
-
-
0033215123
-
Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis
-
Means TK, Wang S, Lien E, Yoshimura A, Golenbock DT, Fenton MJ: Human toll-like receptors mediate cellular activation by Mycobacterium tuberculosis. J Immunol 1999;163:3920-3927.
-
(1999)
J Immunol
, vol.163
, pp. 3920-3927
-
-
Means, T.K.1
Wang, S.2
Lien, E.3
Yoshimura, A.4
Golenbock, D.T.5
Fenton, M.J.6
-
56
-
-
0033198204
-
Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
-
Hirschfeld M, Kirschning CJ, Schwandner R, Wesche H, Weis JH, Wooten RM, Weis JJ: Cutting edge: Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2. J Immunol 1999;163:2382-2386.
-
(1999)
J Immunol
, vol.163
, pp. 2382-2386
-
-
Hirschfeld, M.1
Kirschning, C.J.2
Schwandner, R.3
Wesche, H.4
Weis, J.H.5
Wooten, R.M.6
Weis, J.J.7
-
57
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
-
Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ: Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem 1999;274:17406-17409.
-
(1999)
J Biol Chem
, vol.274
, pp. 17406-17409
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
Rothe, M.4
Kirschning, C.J.5
-
58
-
-
0033618630
-
Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2
-
Aliprantis AO, Yang RB, Mark MR, Suggett S, Devaux B, Radolf JD, Klimpel GR, Godowski P, Zychlinsky A: Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2. Science 1999;285:736-739.
-
(1999)
Science
, vol.285
, pp. 736-739
-
-
Aliprantis, A.O.1
Yang, R.B.2
Mark, M.R.3
Suggett, S.4
Devaux, B.5
Radolf, J.D.6
Klimpel, G.R.7
Godowski, P.8
Zychlinsky, A.9
-
59
-
-
0033618562
-
Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
-
Brightbill HD, Libraty DH, Krutzik SR, Yang RB, Belisle JT, Bleharski JR, Maitland M, Norgard MV, Plevy SE, Smale ST, Brennan PJ, Bloom BR, Godowski PJ, Modlin RL: Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999;285:732-736.
-
(1999)
Science
, vol.285
, pp. 732-736
-
-
Brightbill, H.D.1
Libraty, D.H.2
Krutzik, S.R.3
Yang, R.B.4
Belisle, J.T.5
Bleharski, J.R.6
Maitland, M.7
Norgard, M.V.8
Plevy, S.E.9
Smale, S.T.10
Brennan, P.J.11
Bloom, B.R.12
Godowski, P.J.13
Modlin, R.L.14
-
60
-
-
0033592748
-
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
-
Underhill DM, Ozinsky A, Hajjar AM, Stevens A, Wilson CB, Bassetti M, Aderem A: The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999;401:811-815.
-
(1999)
Nature
, vol.401
, pp. 811-815
-
-
Underhill, D.M.1
Ozinsky, A.2
Hajjar, A.M.3
Stevens, A.4
Wilson, C.B.5
Bassetti, M.6
Aderem, A.7
-
61
-
-
0034651729
-
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide
-
Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A, Espevik T: Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. J Immunol 2000;164:2064-2069.
-
(2000)
J Immunol
, vol.164
, pp. 2064-2069
-
-
Flo, T.H.1
Halaas, O.2
Lien, E.3
Ryan, L.4
Teti, G.5
Golenbock, D.T.6
Sundan, A.7
Espevik, T.8
-
62
-
-
0035871626
-
Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different toll-like receptors independent of paracrine mediators
-
Lehner MD, Morath S, Michelsen KS, Schumann RR, Hartung T: Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different toll-like receptors independent of paracrine mediators. J Immunol 2001;166:5161-5167.
-
(2001)
J Immunol
, vol.166
, pp. 5161-5167
-
-
Lehner, M.D.1
Morath, S.2
Michelsen, K.S.3
Schumann, R.R.4
Hartung, T.5
-
63
-
-
0034662239
-
Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
-
Hirschfeld M, Ma Y, Weis JH, Vogel SN, Weis JJ: Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 2000;165:618-622.
-
(2000)
J Immunol
, vol.165
, pp. 618-622
-
-
Hirschfeld, M.1
Ma, Y.2
Weis, J.H.3
Vogel, S.N.4
Weis, J.J.5
-
64
-
-
0037090077
-
Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling
-
Lee HK, Lee J, Tobias PS: Two lipoproteins extracted from Escherichia coli K-12 LCD25 lipopolysaccharide are the major components responsible for Toll-like receptor 2-mediated signaling. J Immunol 2002;168:4012-4017.
-
(2002)
J Immunol
, vol.168
, pp. 4012-4017
-
-
Lee, H.K.1
Lee, J.2
Tobias, P.S.3
-
65
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
Lien E, Means TK, Heine H, Yoshimura A, Kusumoto S, Fukase K, Fenton MJ, Oikawa M, Qureshi N, Monks B, Finberg RW, Ingalls RR, Golenbock DT: Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J Clin Invest 2000;105:497-504.
-
(2000)
J Clin Invest
, vol.105
, pp. 497-504
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
Fukase, K.6
Fenton, M.J.7
Oikawa, M.8
Qureshi, N.9
Monks, B.10
Finberg, R.W.11
Ingalls, R.R.12
Golenbock, D.T.13
-
66
-
-
0034007076
-
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
-
Poltorak A, Ricciardi-Castagnoli P, Citterio S, Beutler B: Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation. Proc Natl Acad Sci USA 2000;97:2163-2167.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2163-2167
-
-
Poltorak, A.1
Ricciardi-Castagnoli, P.2
Citterio, S.3
Beutler, B.4
-
67
-
-
0035115080
-
Signaling by Toll-Like receptor 2 and 4 agonists results in differential gene expression in murine macrophages
-
Hirschfeld M, Weis JJ, Toshchakov V, Salkowski CA, Cody MJ, Ward DC, Qureshi N, Michalek SM, Vogel SN: Signaling by Toll-Like receptor 2 and 4 agonists results in differential gene expression in murine macrophages. Infect Immun 2001;69:1477-1482.
-
(2001)
Infect Immun
, vol.69
, pp. 1477-1482
-
-
Hirschfeld, M.1
Weis, J.J.2
Toshchakov, V.3
Salkowski, C.A.4
Cody, M.J.5
Ward, D.C.6
Qureshi, N.7
Michalek, S.M.8
Vogel, S.N.9
-
68
-
-
5944225473
-
Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism
-
Werts C, Tapping RI, Mathison JC, Chuang TH, Kravchenko V, Saint Girons I, Haake DA, Godowski PJ, Hayashi F, Ozinsky A, Underhill DM, Kirschning CJ, Wagner H, Aderem A, Tobias PS, Ulevitch RJ: Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism. Nat Immunol 2001;2:346-352.
-
(2001)
Nat Immunol
, vol.2
, pp. 346-352
-
-
Werts, C.1
Tapping, R.I.2
Mathison, J.C.3
Chuang, T.H.4
Kravchenko, V.5
Saint Girons, I.6
Haake, D.A.7
Godowski, P.J.8
Hayashi, F.9
Ozinsky, A.10
Underhill, D.M.11
Kirschning, C.J.12
Wagner, H.13
Aderem, A.14
Tobias, P.S.15
Ulevitch, R.J.16
-
69
-
-
0037439663
-
Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2
-
Girard R, Pedron T, Uematsu S, Balloy V, Chignard M, Akira S, Chaby R: Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2. J Cell Sci 2003;116:293-302.
-
(2003)
J Cell Sci
, vol.116
, pp. 293-302
-
-
Girard, R.1
Pedron, T.2
Uematsu, S.3
Balloy, V.4
Chignard, M.5
Akira, S.6
Chaby, R.7
-
70
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, Tripp RA, Walsh EE, Freeman MW, Golenbock DT, Anderson LJ, Finberg RW: Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000;1:398-401.
-
(2000)
Nat Immunol
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
Haynes, L.M.4
Jones, L.P.5
Tripp, R.A.6
Walsh, E.E.7
Freeman, M.W.8
Golenbock, D.T.9
Anderson, L.J.10
Finberg, R.W.11
-
71
-
-
0001701294
-
Toll-like receptor (TLR)-2 mediates Treponema glycolipid and lipoteichoic acid (LTA)-induced NF-kappa B translocation
-
Opitz B, Schroder NW, Spreitzer I, Michelsen KS, Kirschning CJ, Hallatschek W, Zahringer U, Hartung T, Gobel UB, Schumann RR: Toll-like receptor (TLR)-2 mediates Treponema glycolipid and lipoteichoic acid (LTA)-induced NF-kappa B translocation. J Biol Chem 2001;276:22041-22047.
-
(2001)
J Biol Chem
, vol.276
, pp. 22041-22047
-
-
Opitz, B.1
Schroder, N.W.2
Spreitzer, I.3
Michelsen, K.S.4
Kirschning, C.J.5
Hallatschek, W.6
Zahringer, U.7
Hartung, T.8
Gobel, U.B.9
Schumann, R.R.10
-
72
-
-
0035085495
-
Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae
-
Wang JE, Warris A, Ellingsen EA, Jorgensen PF, Flo TH, Espevik T, Solberg R, Verweij PE, Aasen AO: Involvement of CD14 and toll-like receptors in activation of human monocytes by Aspergillus fumigatus hyphae. Infect Immun 2001;69:2402-2406.
-
(2001)
Infect Immun
, vol.69
, pp. 2402-2406
-
-
Wang, J.E.1
Warris, A.2
Ellingsen, E.A.3
Jorgensen, P.F.4
Flo, T.H.5
Espevik, T.6
Solberg, R.7
Verweij, P.E.8
Aasen, A.O.9
-
73
-
-
0035313274
-
Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule
-
Shoham S, Huang C, Chen JM, Golenbock DT, Levitz SM: Toll-like receptor 4 mediates intracellular signaling without TNF-alpha release in response to Cryptococcus neoformans polysaccharide capsule. J Immunol 2001;166:4620-4626.
-
(2001)
J Immunol
, vol.166
, pp. 4620-4626
-
-
Shoham, S.1
Huang, C.2
Chen, J.M.3
Golenbock, D.T.4
Levitz, S.M.5
-
74
-
-
0035910470
-
A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway
-
Lien E, Chow JC, Hawkins LD, McGuinness PD, Miyake K, Espevik T, Gusovsky F, Golenbock DT: A novel synthetic acyclic lipid A-like agonist activates cells via the lipopolysaccharide/Toll-like receptor 4 signaling pathway. J Biol Chem 2001;276:1873-1880.
-
(2001)
J Biol Chem
, vol.276
, pp. 1873-1880
-
-
Lien, E.1
Chow, J.C.2
Hawkins, L.D.3
McGuinness, P.D.4
Miyake, K.5
Espevik, T.6
Gusovsky, F.7
Golenbock, D.T.8
-
75
-
-
0034723186
-
Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol
-
Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K, Nishijima M: Mouse toll-like receptor 4.MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by Taxol. J Biol Chem 2000;275:2251-2254.
-
(2000)
J Biol Chem
, vol.275
, pp. 2251-2254
-
-
Kawasaki, K.1
Akashi, S.2
Shimazu, R.3
Yoshida, T.4
Miyake, K.5
Nishijima, M.6
-
76
-
-
0035173628
-
CD11b/CD18 acts in concert with CD14 and toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression
-
Perera PY, Mayadas TN, Takeuchi O, Akira S, Zaks-Zilberman M, Goyert SM, Vogel SN: CD11b/CD18 acts in concert with CD14 and toll-like receptor (TLR) 4 to elicit full lipopolysaccharide and taxol-inducible gene expression. J Immunol 2001;166:574-581.
-
(2001)
J Immunol
, vol.166
, pp. 574-581
-
-
Perera, P.Y.1
Mayadas, T.N.2
Takeuchi, O.3
Akira, S.4
Zaks-Zilberman, M.5
Goyert, S.M.6
Vogel, S.N.7
-
77
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
-
Ohashi K, Burkart V, Flohe S, Kolb H: Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000;164:558-561.
-
(2000)
J Immunol
, vol.164
, pp. 558-561
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
78
-
-
0037177833
-
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway
-
Vabulas RM, Ahmad-Nejad P, Ghose S, Kirschning CJ, Issels RD, Wagner H: HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J Biol Chem 2002;277:15107-15112.
-
(2002)
J Biol Chem
, vol.277
, pp. 15107-15112
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Ghose, S.3
Kirschning, C.J.4
Issels, R.D.5
Wagner, H.6
-
79
-
-
0035903158
-
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells
-
Vabulas RM, Ahmad-Nejad P, Da Costa C, Miethke T, Kirschning CJ, Hacker H, Wagner H: Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J Biol Chem 2001;276:31332-31339.
-
(2001)
J Biol Chem
, vol.276
, pp. 31332-31339
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Da Costa, C.3
Miethke, T.4
Kirschning, C.J.5
Hacker, H.6
Wagner, H.7
-
80
-
-
0037065909
-
Inflammatory response after open heart surgery: Release of heat-shock protein 70 and signaling through toll-like receptor-4
-
Dybdahl B, Wahba A, Lien E, Flo TH, Waage A, Qureshi N, Sellevold OF, Espevik T, Sundan A: Inflammatory response after open heart surgery: Release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation 2002;105:685-690.
-
(2002)
Circulation
, vol.105
, pp. 685-690
-
-
Dybdahl, B.1
Wahba, A.2
Lien, E.3
Flo, T.H.4
Waage, A.5
Qureshi, N.6
Sellevold, O.F.7
Espevik, T.8
Sundan, A.9
-
81
-
-
0035971217
-
The extra domain A of fibronectin activates Toll-like receptor 4
-
Okamura Y, Watari M, Jerud ES, Young DW, Ishizaka ST, Rose J, Chow JC, Strauss JF: The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001;276:10229-10233.
-
(2001)
J Biol Chem
, vol.276
, pp. 10229-10233
-
-
Okamura, Y.1
Watari, M.2
Jerud, E.S.3
Young, D.W.4
Ishizaka, S.T.5
Rose, J.6
Chow, J.C.7
Strauss, J.F.8
-
82
-
-
0035451118
-
Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4
-
Smiley ST, King JA, Hancock WW: Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4. J Immunol 2001;167:2887-2894.
-
(2001)
J Immunol
, vol.167
, pp. 2887-2894
-
-
Smiley, S.T.1
King, J.A.2
Hancock, W.W.3
-
83
-
-
0037097672
-
Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4
-
Guillot L, Balloy V, McCormack FX, Golenbock DT, Chignard M, Si-Tahar M: Cutting edge: The immunostimulatory activity of the lung surfactant protein-A involves Toll-like receptor 4. J Immunol 2002;168:5989-5992.
-
(2002)
J Immunol
, vol.168
, pp. 5989-5992
-
-
Guillot, L.1
Balloy, V.2
McCormack, F.X.3
Golenbock, D.T.4
Chignard, M.5
Si-Tahar, M.6
-
84
-
-
0037033364
-
Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4
-
Termeer C, Benedix F, Sleeman J, Fieber C, Voith U, Ahrens T, Miyake K, Freudenberg M, Galanos C, Simon JC: Oligosaccharides of hyaluronan activate dendritic cells via toll-like receptor 4. J Exp Med 2002;195:99-111.
-
(2002)
J Exp Med
, vol.195
, pp. 99-111
-
-
Termeer, C.1
Benedix, F.2
Sleeman, J.3
Fieber, C.4
Voith, U.5
Ahrens, T.6
Miyake, K.7
Freudenberg, M.8
Galanos, C.9
Simon, J.C.10
-
85
-
-
0036829687
-
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2
-
Biragyn A, Ruffini PA, Leifer CA, Klyushnenkova E, Shakhov A, Chertov O, Shirakawa AK, Farber JM, Segal DM, Oppenheim JJ, Kwak LW: Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science 2002;298:1025-1029.
-
(2002)
Science
, vol.298
, pp. 1025-1029
-
-
Biragyn, A.1
Ruffini, P.A.2
Leifer, C.A.3
Klyushnenkova, E.4
Shakhov, A.5
Chertov, O.6
Shirakawa, A.K.7
Farber, J.M.8
Segal, D.M.9
Oppenheim, J.J.10
Kwak, L.W.11
-
86
-
-
0036849121
-
Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway
-
Ogawa T, Asai Y, Hashimoto M, Takeuchi O, Kurita T, Yoshikai Y, Miyake K, Akira S: Cell activation by Porphyromonas gingivalis lipid A molecule through Toll-like receptor 4- and myeloid differentiation factor 88-dependent signaling pathway. Int Immunol 2002;14:1325-1332.
-
(2002)
Int Immunol
, vol.14
, pp. 1325-1332
-
-
Ogawa, T.1
Asai, Y.2
Hashimoto, M.3
Takeuchi, O.4
Kurita, T.5
Yoshikai, Y.6
Miyake, K.7
Akira, S.8
-
87
-
-
0036499004
-
Heat-shock proteins as activators of the innate immune system
-
Wallin RP, Lundqvist A, More SH, von Bonin A, Kiessling R, Ljunggren HG: Heat-shock proteins as activators of the innate immune system. Trends Immunol 2002;23:130-135.
-
(2002)
Trends Immunol
, vol.23
, pp. 130-135
-
-
Wallin, R.P.1
Lundqvist, A.2
More, S.H.3
Von Bonin, A.4
Kiessling, R.5
Ljunggren, H.G.6
-
88
-
-
0037414787
-
Endotoxin contamination in recombinant human Hsp70 preparation is responsible for the induction of TNFalpha release by murine macrophages
-
Gao B, Tsan MF: Endotoxin contamination in recombinant human Hsp70 preparation is responsible for the induction of TNFalpha release by murine macrophages. J Biol Chem 2003;278:174-179.
-
(2003)
J Biol Chem
, vol.278
, pp. 174-179
-
-
Gao, B.1
Tsan, M.F.2
-
89
-
-
0036644042
-
Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins
-
Takeuchi O, Sato S, Horiuchi T, Hoshino K, Takeda K, Dong Z, Modlin RL, Akira S: Cutting edge: Role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J Immunol 2002;169:10-14.
-
(2002)
J Immunol
, vol.169
, pp. 10-14
-
-
Takeuchi, O.1
Sato, S.2
Horiuchi, T.3
Hoshino, K.4
Takeda, K.5
Dong, Z.6
Modlin, R.L.7
Akira, S.8
-
90
-
-
0036344106
-
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
-
Alexopoulou L, Thomas V, Schnare M, Lobet Y, Anguita J, Schoen RT, Medzhitov R, Fikrig E, Flavell RA: Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med 2002;8:878-884.
-
(2002)
Nat Med
, vol.8
, pp. 878-884
-
-
Alexopoulou, L.1
Thomas, V.2
Schnare, M.3
Lobet, Y.4
Anguita, J.5
Schoen, R.T.6
Medzhitov, R.7
Fikrig, E.8
Flavell, R.A.9
-
91
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA: Recognition of double-stranded RNA and activation of NF-kappaB by Toll- like receptor 3. Nature 2001;413:732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
92
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F, Smith KD, Ozinsky A, Hawn TR, Yi EC, Goodlett DR, Eng JK, Akira S, Underhill DM, Aderem A: The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001;410:1099-1103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
93
-
-
0034922923
-
Discrimination of bacterial lipoproteins by Toll-like receptor 6
-
Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S: Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 2001;13:933-940.
-
(2001)
Int Immunol
, vol.13
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
Takeda, K.7
Akira, S.8
-
94
-
-
0035892912
-
Novel engagement of CD14 and multiple toll-like receptors by group B streptococci
-
Henneke P, Takeuchi O, van Strijp JA, Guttormsen HK, Smith JA, Schromm AB, Espevik TA, Akira S, Nizet V, Kasper DL, Golenbock DT: Novel engagement of CD14 and multiple toll-like receptors by group B streptococci. J Immunol 2001;167:7069-7076.
-
(2001)
J Immunol
, vol.167
, pp. 7069-7076
-
-
Henneke, P.1
Takeuchi, O.2
Van Strijp, J.A.3
Guttormsen, H.K.4
Smith, J.A.5
Schromm, A.B.6
Espevik, T.A.7
Akira, S.8
Nizet, V.9
Kasper, D.L.10
Golenbock, D.T.11
-
95
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, Horiuchi T, Tomizawa H, Takeda K, Akira S: Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002;3:196-200.
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
96
-
-
0036088492
-
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
-
Jurk M, Heil F, Vollmer J, Schetter C, Krieg AM, Wagner H, Lipford G, Bauer S: Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002;3:499.
-
(2002)
Nat Immunol
, vol.3
, pp. 499
-
-
Jurk, M.1
Heil, F.2
Vollmer, J.3
Schetter, C.4
Krieg, A.M.5
Wagner, H.6
Lipford, G.7
Bauer, S.8
-
97
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S: A Toll-like receptor recognizes bacterial DNA. Nature 2000;408:740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
98
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: Transfer from CD14 to TLR4 and MD-2
-
da Silva CJ, Soldau K, Christen U, Tobias PS, Ulevitch RJ: Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: Transfer from CD14 to TLR4 and MD-2. J Biol Chem 2001;276:21129-21135.
-
(2001)
J Biol Chem
, vol.276
, pp. 21129-21135
-
-
Da Silva, C.J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
99
-
-
0035979192
-
Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition
-
Bauer S, Kirschning CJ, Hacker H, Redecke V, Hausmann S, Akira S, Wagner H, Lipford GB: Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition. Proc Natl Acad Sci USA 2001;98:9237-9242.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9237-9242
-
-
Bauer, S.1
Kirschning, C.J.2
Hacker, H.3
Redecke, V.4
Hausmann, S.5
Akira, S.6
Wagner, H.7
Lipford, G.B.8
-
100
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
-
Ozinsky A, Underhill DM, Fontenot JD, Hajjar AM, Smith KD, Wilson CB, Schroeder L, Aderem A: The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors. Proc Natl Acad Sci USA 2000;97:13766-13771.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 13766-13771
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
101
-
-
0035796406
-
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling
-
Schromm AB, Lien E, Henneke P, Chow JC, Yoshimura A, Heine H, Latz E, Monks BG, Schwartz DA, Miyake K, Golenbock DT: Molecular genetic analysis of an endotoxin nonresponder mutant cell line: A point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling. J Exp Med 2001;194:79-88.
-
(2001)
J Exp Med
, vol.194
, pp. 79-88
-
-
Schromm, A.B.1
Lien, E.2
Henneke, P.3
Chow, J.C.4
Yoshimura, A.5
Heine, H.6
Latz, E.7
Monks, B.G.8
Schwartz, D.A.9
Miyake, K.10
Golenbock, D.T.11
-
102
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M: MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999;189:1777-1782.
-
(1999)
J Exp Med
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
103
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M, Ogata M, Iwakura Y, Akira S, Kitamura T, Kosugi A, Kimoto M, Miyake K: Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol 2002;3:667-672.
-
(2002)
Nat Immunol
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
Kitamura, T.7
Kosugi, A.8
Kimoto, M.9
Miyake, K.10
-
104
-
-
0035834135
-
Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4
-
Visintin A, Mazzoni A, Spitzer JA, Segal DM: Secreted MD-2 is a large polymeric protein that efficiently confers lipopolysaccharide sensitivity to Toll-like receptor 4. Proc Natl Acad Sci USA 2001;98:12156-12161.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12156-12161
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.A.3
Segal, D.M.4
-
105
-
-
43949176031
-
CD14: Cell surface receptor and differentiation marker
-
Ziegler-Heitbrock HWL, Ulevitch RJ: CD14: Cell surface receptor and differentiation marker. Immunol Today 1993;14/3:121-125.
-
(1993)
Immunol Today
, vol.14
, Issue.3
, pp. 121-125
-
-
Ziegler-Heitbrock, H.W.L.1
Ulevitch, R.J.2
-
106
-
-
0025290213
-
Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6
-
Lord KA, Hoffman-Liebermann B, Liebermann DA: Nucleotide sequence and expression of a cDNA encoding MyD88, a novel myeloid differentiation primary response gene induced by IL6. Oncogene 1990;5:1095-1097.
-
(1990)
Oncogene
, vol.5
, pp. 1095-1097
-
-
Lord, K.A.1
Hoffman-Liebermann, B.2
Liebermann, D.A.3
-
107
-
-
0028237775
-
Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family
-
Hultmark D: Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family. Biochem Biophys Res Commun 1994;199:144-146.
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 144-146
-
-
Hultmark, D.1
-
108
-
-
0028982919
-
NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity
-
Croston GE, Cao Z, Goeddel DV: NF-kappa B activation by interleukin-1 (IL-1) requires an IL-1 receptor-associated protein kinase activity. J Biol Chem 1995;270:16514-16517.
-
(1995)
J Biol Chem
, vol.270
, pp. 16514-16517
-
-
Croston, G.E.1
Cao, Z.2
Goeddel, D.V.3
-
109
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao Z, Henzel WJ, Gao X: IRAK: A kinase associated with the interleukin-1 receptor. Science 1996;271:1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
110
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z, Xiong J, Takeuchi M, Kurama T, Goeddel DV: TRAF6 is a signal transducer for interleukin-1. Nature 1996;383:443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
111
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, Ghosh S, Janeway CA Jr: MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell 1998;2:253-258.
-
(1998)
Mol Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway C.A., Jr.7
-
112
-
-
0034597766
-
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
-
Xu Y, Tao X, Shen B, Horng T, Medzhitov R, Manley JL, Tong L: Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature 2000;408:111-115.
-
(2000)
Nature
, vol.408
, pp. 111-115
-
-
Xu, Y.1
Tao, X.2
Shen, B.3
Horng, T.4
Medzhitov, R.5
Manley, J.L.6
Tong, L.7
-
113
-
-
0032524335
-
MyD88, an adapter protein involved in interleukin-1 signaling
-
Burns K, Martinon F, Esslinger C, Pahl H, Schneider P, Bodmer JL, Di Marco F, French L, Tschopp J: MyD88, an adapter protein involved in interleukin-1 signaling. J Biol Chem 1998;273:12203-12209.
-
(1998)
J Biol Chem
, vol.273
, pp. 12203-12209
-
-
Burns, K.1
Martinon, F.2
Esslinger, C.3
Pahl, H.4
Schneider, P.5
Bodmer, J.L.6
Di Marco, F.7
French, L.8
Tschopp, J.9
-
114
-
-
0037117543
-
IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase
-
Li S, Strelow A, Fontana EJ, Wesche H: IRAK-4: A novel member of the IRAK family with the properties of an IRAK-kinase. Proc Natl Acad Sci USA 2002;99:5567-5572.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5567-5572
-
-
Li, S.1
Strelow, A.2
Fontana, E.J.3
Wesche, H.4
-
115
-
-
0033516561
-
IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family
-
Wesche H, Gao X, Li X, Kirschning CJ, Stark GR, Cao Z: IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family. J Biol Chem 1999;274:19403-19410.
-
(1999)
J Biol Chem
, vol.274
, pp. 19403-19410
-
-
Wesche, H.1
Gao, X.2
Li, X.3
Kirschning, C.J.4
Stark, G.R.5
Cao, Z.6
-
116
-
-
0032526555
-
Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production
-
Kanakaraj P, Schafer PH, Cavender DE, Wu Y, Ngo K, Grealish PF, Wadsworth SA, Peterson PA, Siekierka JJ, Harris CA, Fung-Leung WP: Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production. J Exp Med 1998;187:2073-2079.
-
(1998)
J Exp Med
, vol.187
, pp. 2073-2079
-
-
Kanakaraj, P.1
Schafer, P.H.2
Cavender, D.E.3
Wu, Y.4
Ngo, K.5
Grealish, P.F.6
Wadsworth, S.A.7
Peterson, P.A.8
Siekierka, J.J.9
Harris, C.A.10
Fung-Leung, W.P.11
-
117
-
-
0033565779
-
Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase
-
Thomas JA, Allen JL, Tsen M, Dubnicoff T, Danao J, Liao XC, Cao Z, Wasserman SA: Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase. J Immunol 1999;163:978-984.
-
(1999)
J Immunol
, vol.163
, pp. 978-984
-
-
Thomas, J.A.1
Allen, J.L.2
Tsen, M.3
Dubnicoff, T.4
Danao, J.5
Liao, X.C.6
Cao, Z.7
Wasserman, S.A.8
-
118
-
-
0033002994
-
Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase
-
Li X, Commane M, Burns C, Vithalani K, Cao Z, Stark GR: Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase. Mol Cell Biol 1999;19:4643-4652.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 4643-4652
-
-
Li, X.1
Commane, M.2
Burns, C.3
Vithalani, K.4
Cao, Z.5
Stark, G.R.6
-
119
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki N, Suzuki S, Duncan GS, Millar DG, Wada T, Mirtsos C, Takada H, Wakeham A, Itie A, Li S, Penninger JM, Wesche H, Ohashi PS, Mak TW, Yeh WC: Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature 2002;416:750-756.
-
(2002)
Nature
, vol.416
, pp. 750-756
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
Millar, D.G.4
Wada, T.5
Mirtsos, C.6
Takada, H.7
Wakeham, A.8
Itie, A.9
Li, S.10
Penninger, J.M.11
Wesche, H.12
Ohashi, P.S.13
Mak, T.W.14
Yeh, W.C.15
-
120
-
-
0037178785
-
IRAK-M is a negative regulator of Toll-like receptor signaling
-
Kobayashi K, Hernandez LD, Galan JE, Janeway CA Jr, Medzhitov R, Flavell RA: IRAK-M is a negative regulator of Toll-like receptor signaling. Cell 2002;110:191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galan, J.E.3
Janeway C.A., Jr.4
Medzhitov, R.5
Flavell, R.A.6
-
121
-
-
0033776154
-
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor
-
Burns K, Clatworthy J, Martin L, Martinon F, Plumpton C, Maschera B, Lewis A, Ray K, Tschopp J, Volpe F: Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor. Nat Cell Biol 2000;2:346-351.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 346-351
-
-
Burns, K.1
Clatworthy, J.2
Martin, L.3
Martinon, F.4
Plumpton, C.5
Maschera, B.6
Lewis, A.7
Ray, K.8
Tschopp, J.9
Volpe, F.10
-
122
-
-
0035879283
-
Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling
-
Bulut Y, Faure E, Thomas L, Equils O, Arditi M: Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor signaling molecules in Toll-like receptor 2 signaling. J Immunol 2001;167:987-994.
-
(2001)
J Immunol
, vol.167
, pp. 987-994
-
-
Bulut, Y.1
Faure, E.2
Thomas, L.3
Equils, O.4
Arditi, M.5
-
123
-
-
0036510366
-
Negative regulation of toll-like receptor-mediated signaling by Tollip
-
Zhang G, Ghosh S: Negative regulation of toll-like receptor-mediated signaling by Tollip. J Biol Chem 2002;277:7059-7065.
-
(2002)
J Biol Chem
, vol.277
, pp. 7059-7065
-
-
Zhang, G.1
Ghosh, S.2
-
124
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
Lomaga MA, Yeh WC, Sarosi I, Duncan GS, Furlonger C, Ho A, Morony S, Capparelli C, Van G, Kaufman S, van der Heiden A, Itie A, Wakeham A, Khoo W, Sasaki T, Cao Z, Penninger JM, Paige CJ, Lacey DL, Dunstan CR, Boyle WJ, Goeddel DV, Mak TW: TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev 1999;13:1015-1024.
-
(1999)
Genes Dev
, vol.13
, pp. 1015-1024
-
-
Lomaga, M.A.1
Yeh, W.C.2
Sarosi, I.3
Duncan, G.S.4
Furlonger, C.5
Ho, A.6
Morony, S.7
Capparelli, C.8
Van, G.9
Kaufman, S.10
Van Der Heiden, A.11
Itie, A.12
Wakeham, A.13
Khoo, W.14
Sasaki, T.15
Cao, Z.16
Penninger, J.M.17
Paige, C.J.18
Lacey, D.L.19
Dunstan, C.R.20
Boyle, W.J.21
Goeddel, D.V.22
Mak, T.W.23
more..
-
125
-
-
6544270833
-
Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice
-
Naito A, Azuma S, Tanaka S, Miyazaki T, Takaki S, Takatsu K, Nakao K, Nakamura K, Katsuki M, Yamamoto T, Inoue J: Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells 1999;4:353-362.
-
(1999)
Genes Cells
, vol.4
, pp. 353-362
-
-
Naito, A.1
Azuma, S.2
Tanaka, S.3
Miyazaki, T.4
Takaki, S.5
Takatsu, K.6
Nakao, K.7
Nakamura, K.8
Katsuki, M.9
Yamamoto, T.10
Inoue, J.11
-
126
-
-
0034644474
-
Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique poly-ubiquitin chain
-
Deng L, Wang C, Spencer E, Yang L, Braun A, You J, Slaughter C, Pickart C, Chen ZJ: Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique poly-ubiquitin chain. Cell 2000;103:351-361.
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
You, J.6
Slaughter, C.7
Pickart, C.8
Chen, Z.J.9
-
127
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ: TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 2001;412:346-351.
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
128
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K: Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 1995;270:2008-2011.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
Irie, K.4
Oishi, I.5
Ueno, N.6
Taniguchi, T.7
Nishida, E.8
Matsumoto, K.9
-
129
-
-
0033580466
-
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway
-
Ninomiya-Tsuji J, Kishimoto K, Hiyama A, Inoue J, Cao Z, Matsumoto K: The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature 1999;398:252-256.
-
(1999)
Nature
, vol.398
, pp. 252-256
-
-
Ninomiya-Tsuji, J.1
Kishimoto, K.2
Hiyama, A.3
Inoue, J.4
Cao, Z.5
Matsumoto, K.6
-
130
-
-
0029940355
-
TAB1: An activator of the TAK1 MAPKKK in TGF-beta signal transduction
-
Shibuya H, Yamaguchi K, Shirakabe K, Tonegawa A, Gotoh Y, Ueno N, Irie K, Nishida E, Matsumoto K: TAB1: An activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science 1996;272:1179-1182.
-
(1996)
Science
, vol.272
, pp. 1179-1182
-
-
Shibuya, H.1
Yamaguchi, K.2
Shirakabe, K.3
Tonegawa, A.4
Gotoh, Y.5
Ueno, N.6
Irie, K.7
Nishida, E.8
Matsumoto, K.9
-
131
-
-
0033634977
-
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway
-
Takaesu G, Kishida S, Hiyama A, Yamaguchi K, Shibuya H, Irie K, Ninomiya-Tsuji J, Matsumoto K: TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell 2000;5:649-658.
-
(2000)
Mol Cell
, vol.5
, pp. 649-658
-
-
Takaesu, G.1
Kishida, S.2
Hiyama, A.3
Yamaguchi, K.4
Shibuya, H.5
Irie, K.6
Ninomiya-Tsuji, J.7
Matsumoto, K.8
-
132
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S: Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999;11:115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
133
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
Kawai T, Takeuchi O, Fujita T, Inoue J, Muhlradt PF, Sato S, Hoshino K, Akira S: Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes. J Immunol 2001;167:5887-5894.
-
(2001)
J Immunol
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
134
-
-
0034698739
-
Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6
-
Hacker H, Vabulas RM, Takeuchi O, Hoshino K, Akira S, Wagner H: Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6. J Exp Med 2000;192:595-600.
-
(2000)
J Exp Med
, vol.192
, pp. 595-600
-
-
Hacker, H.1
Vabulas, R.M.2
Takeuchi, O.3
Hoshino, K.4
Akira, S.5
Wagner, H.6
-
135
-
-
0034650420
-
Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway
-
Takeuchi O, Kaufmann A, Grote K, Kawai T, Hoshino K, Morr M, Muhlradt PF, Akira S: Cutting edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a toll-like receptor 2- and MyD88-dependent signaling pathway. J Immunol 2000;164:554-557.
-
(2000)
J Immunol
, vol.164
, pp. 554-557
-
-
Takeuchi, O.1
Kaufmann, A.2
Grote, K.3
Kawai, T.4
Hoshino, K.5
Morr, M.6
Muhlradt, P.F.7
Akira, S.8
-
136
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng T, Barton GM, Medzhitov R: TIRAP: An adapter molecule in the Toll signaling pathway. Nat Immunol 2001;2:835-841.
-
(2001)
Nat Immunol
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
137
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA: Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001;413:78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
McMurray, D.11
Smith, D.E.12
Sims, J.E.13
Bird, T.A.14
O'Neill, L.A.15
-
138
-
-
0037165642
-
Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide
-
Shinobu N, Iwamura T, Yoneyama M, Yamaguchi K, Suhara W, Fukuhara Y, Amano F, Fujita T: Involvement of TIRAP/MAL in signaling for the activation of interferon regulatory factor 3 by lipopolysaccharide. FEBS Lett 2002;517:251-256.
-
(2002)
FEBS Lett
, vol.517
, pp. 251-256
-
-
Shinobu, N.1
Iwamura, T.2
Yoneyama, M.3
Yamaguchi, K.4
Suhara, W.5
Fukuhara, Y.6
Amano, F.7
Fujita, T.8
-
139
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng T, Barton GM, Flavell RA, Medzhitov R: The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002;420:329-333.
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
140
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, Hoshino K, Takeuchi O, Kobayashi M, Fujita T, Takeda K, Akira S: Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002;420:324-329.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
Hoshino, K.7
Takeuchi, O.8
Kobayashi, M.9
Fujita, T.10
Takeda, K.11
Akira, S.12
-
141
-
-
18644376284
-
IRF3 mediates a TLR3/TLR4-specific antiviral gene program
-
Doyle S, Vaidya S, O'Connell R, Dadgostar H, Dempsey P, Wu T, Rao G, Sun R, Haberland M, Modlin R, Cheng G: IRF3 mediates a TLR3/TLR4-specific antiviral gene program. Immunity 2002;17:251-263.
-
(2002)
Immunity
, vol.17
, pp. 251-263
-
-
Doyle, S.1
Vaidya, S.2
O'Connell, R.3
Dadgostar, H.4
Dempsey, P.5
Wu, T.6
Rao, G.7
Sun, R.8
Haberland, M.9
Modlin, R.10
Cheng, G.11
-
142
-
-
0036222241
-
TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages
-
Toshchakov V, Jones BW, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN: TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. Nat Immunol 2002;3:392-398.
-
(2002)
Nat Immunol
, vol.3
, pp. 392-398
-
-
Toshchakov, V.1
Jones, B.W.2
Perera, P.Y.3
Thomas, K.4
Cody, M.J.5
Zhang, S.6
Williams, B.R.7
Major, J.8
Hamilton, T.A.9
Fenton, M.J.10
Vogel, S.N.11
-
143
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S: Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 2002;169:6668-6672.
-
(2002)
J Immunol
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
144
-
-
0034577944
-
Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway
-
Arbibe L, Mira JP, Teusch N, Kline L, Guha M, Mackman N, Godowski PJ, Ulevitch RJ, Knaus UG: Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway. Nat Immunol 2000;1:533-540.
-
(2000)
Nat Immunol
, vol.1
, pp. 533-540
-
-
Arbibe, L.1
Mira, J.P.2
Teusch, N.3
Kline, L.4
Guha, M.5
Mackman, N.6
Godowski, P.J.7
Ulevitch, R.J.8
Knaus, U.G.9
-
145
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
Kobayashi K, Inohara N, Hernandez LD, Galan JE, Nunez G, Janeway CA, Medzhitov R, Flavell RA: RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature 2002;416:194-199.
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
Inohara, N.2
Hernandez, L.D.3
Galan, J.E.4
Nunez, G.5
Janeway, C.A.6
Medzhitov, R.7
Flavell, R.A.8
-
146
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, Cheng G: Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature 2002;416:190-194.
-
(2002)
Nature
, vol.416
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
Cheng, G.6
-
147
-
-
0035877256
-
Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs
-
Dalpke AH, Opper S, Zimmermann S, Heeg K: Suppressors of cytokine signaling (SOCS)-1 and SOCS-3 are induced by CpG-DNA and modulate cytokine responses in APCs. J Immunol 2001;166:7082-7089.
-
(2001)
J Immunol
, vol.166
, pp. 7082-7089
-
-
Dalpke, A.H.1
Opper, S.2
Zimmermann, S.3
Heeg, K.4
-
148
-
-
0034234797
-
Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: Partial role of autocrine/paracrine interferon-alpha/beta
-
Crespo A, Filla MB, Russell SW, Murphy WJ: Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: Partial role of autocrine/paracrine interferon-alpha/beta. Biochem J 2000;349:99-104.
-
(2000)
Biochem J
, vol.349
, pp. 99-104
-
-
Crespo, A.1
Filla, M.B.2
Russell, S.W.3
Murphy, W.J.4
-
149
-
-
0036850946
-
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation
-
Kinjyo I, Hanada T, Inagaki-Ohara K, Mori H, Aki D, Ohishi M, Yoshida H, Kubo M, Yoshimura A: SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 2002;17:583-591.
-
(2002)
Immunity
, vol.17
, pp. 583-591
-
-
Kinjyo, I.1
Hanada, T.2
Inagaki-Ohara, K.3
Mori, H.4
Aki, D.5
Ohishi, M.6
Yoshida, H.7
Kubo, M.8
Yoshimura, A.9
-
150
-
-
18744371050
-
SOCS-1 participates in negative regulation of LPS responses
-
Nakagawa R, Naka T, Tsutsui H, Fujimoto M, Kimura A, Abe T, Seki E, Sato S, Takeuchi O, Takeda K, Akira S, Yamanishi K, Kawase I, Nakanishi K, Kishimoto T: SOCS-1 participates in negative regulation of LPS responses. Immunity 2002;17:677-687.
-
(2002)
Immunity
, vol.17
, pp. 677-687
-
-
Nakagawa, R.1
Naka, T.2
Tsutsui, H.3
Fujimoto, M.4
Kimura, A.5
Abe, T.6
Seki, E.7
Sato, S.8
Takeuchi, O.9
Takeda, K.10
Akira, S.11
Yamanishi, K.12
Kawase, I.13
Nakanishi, K.14
Kishimoto, T.15
-
151
-
-
0034022264
-
The role of dendritic cells in the innate immune system
-
Clark GJ, Angel N, Kato M, Lopez JA, MacDonald K, Vuckovic S, Hart DN: The role of dendritic cells in the innate immune system. Microbes Infect 2000;2:257-272.
-
(2000)
Microbes Infect
, vol.2
, pp. 257-272
-
-
Clark, G.J.1
Angel, N.2
Kato, M.3
Lopez, J.A.4
MacDonald, K.5
Vuckovic, S.6
Hart, D.N.7
-
152
-
-
0034123135
-
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
-
Muzio M, Bosisio D, Polentarutti N, D'amico G, Stoppacciaro A, Mancinelli R, van't Veer C, Penton-Rol G, Ruco LP, Allavena P, Mantovani A: Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells. J Immunol 2000;164:5998-6004.
-
(2000)
J Immunol
, vol.164
, pp. 5998-6004
-
-
Muzio, M.1
Bosisio, D.2
Polentarutti, N.3
D'amico, G.4
Stoppacciaro, A.5
Mancinelli, R.6
Van't Veer, C.7
Penton-Rol, G.8
Ruco, L.P.9
Allavena, P.10
Mantovani, A.11
-
153
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau J, Steinman RM: Dendritic cells and the control of immunity. Nature 1998;392:245-252.
-
(1998)
Nature
, vol.392
, pp. 245-252
-
-
Banchereau, J.1
Steinman, R.M.2
-
154
-
-
0026643596
-
Interleukin-5, eosinophils, and disease
-
Sanderson CJ: Interleukin-5, eosinophils, and disease. Blood 1992;79:3101-3109.
-
(1992)
Blood
, vol.79
, pp. 3101-3109
-
-
Sanderson, C.J.1
-
155
-
-
0028170510
-
TH2 and 'TH2-like' cells in allergy and asthma: Pharmacological perspectives
-
Anderson GP, Coyle AJ: TH2 and 'TH2-like' cells in allergy and asthma: Pharmacological perspectives. Trends Pharmacol Sci 1994;15:324-332.
-
(1994)
Trends Pharmacol Sci
, vol.15
, pp. 324-332
-
-
Anderson, G.P.1
Coyle, A.J.2
-
156
-
-
0033604656
-
Induction and regulation of the IgE response
-
Corry DB, Kheradmand F: Induction and regulation of the IgE response. Nature 1999;402:B18-B23.
-
(1999)
Nature
, vol.402
-
-
Corry, D.B.1
Kheradmand, F.2
-
157
-
-
0037136537
-
The effect of infections on susceptibility to autoimmune and allergic diseases
-
Bach JF: The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002;347:911-920.
-
(2002)
N Engl J Med
, vol.347
, pp. 911-920
-
-
Bach, J.F.1
-
158
-
-
0013876963
-
Epidemiological study of multiple sclerosis in Israel. II. Multiple sclerosis and level of sanitation
-
Leibowitz U, Antonovsky A, Medalie JM, Smith HA, Halpern L, Alter M: Epidemiological study of multiple sclerosis in Israel. II. Multiple sclerosis and level of sanitation. J Neurol Neurosurg Psychiatry 1966;29:60-68.
-
(1966)
J Neurol Neurosurg Psychiatry
, vol.29
, pp. 60-68
-
-
Leibowitz, U.1
Antonovsky, A.2
Medalie, J.M.3
Smith, H.A.4
Halpern, L.5
Alter, M.6
-
159
-
-
0024417450
-
Hay fever, hygiene, and household size
-
Strachan DP: Hay fever, hygiene, and household size. Br Med J 1989;299:1259-1260.
-
(1989)
Br Med J
, vol.299
, pp. 1259-1260
-
-
Strachan, D.P.1
-
160
-
-
0033974824
-
Reduced risk of hay fever and asthma among children of farmers
-
Von Ehrenstein OS, von Mutius E, Illi S, Baumann L, Bohm O, von Kries R: Reduced risk of hay fever and asthma among children of farmers. Clin Exp Allergy 2000;30:187-193.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 187-193
-
-
Von Ehrenstein, O.S.1
Von Mutius, E.2
Illi, S.3
Baumann, L.4
Bohm, O.5
Von Kries, R.6
-
161
-
-
0033856713
-
Exposure to endotoxin or other bacterial components might protect against the development of atopy
-
von Mutius E, Braun-Fahrlander C, Schierl R, Riedler J, Ehlermann S, Maisch S, Waser M, Nowak D: Exposure to endotoxin or other bacterial components might protect against the development of atopy. Clin Exp Allergy 2000;30:1230-1234.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 1230-1234
-
-
Von Mutius, E.1
Braun-Fahrlander, C.2
Schierl, R.3
Riedler, J.4
Ehlermann, S.5
Maisch, S.6
Waser, M.7
Nowak, D.8
-
162
-
-
0035901102
-
Early childhood infectious diseases and the development of asthma up to school age: A birth cohort study
-
Illi S, von Mutius E, Lau S, Bergmann R, Niggemann B, Sommerfeld C, Wahn U: Early childhood infectious diseases and the development of asthma up to school age: A birth cohort study. Br Med J 2001;322:390-395.
-
(2001)
Br Med J
, vol.322
, pp. 390-395
-
-
Illi, S.1
Von Mutius, E.2
Lau, S.3
Bergmann, R.4
Niggemann, B.5
Sommerfeld, C.6
Wahn, U.7
-
163
-
-
0037136585
-
Environmental exposure to endotoxin and its relation to asthma in school-age children
-
Braun-Fahrlander C, Riedler J, Herz U, Eder W, Waser M, Grize L, Maisch S, Carr D, Gerlach F, Bufe A, Lauener RP, Schierl R, Renz H, Nowak D, von Mutius E: Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-877.
-
(2002)
N Engl J Med
, vol.347
, pp. 869-877
-
-
Braun-Fahrlander, C.1
Riedler, J.2
Herz, U.3
Eder, W.4
Waser, M.5
Grize, L.6
Maisch, S.7
Carr, D.8
Gerlach, F.9
Bufe, A.10
Lauener, R.P.11
Schierl, R.12
Renz, H.13
Nowak, D.14
Von Mutius, E.15
-
164
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R: Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2001;2:947-950.
-
(2001)
Nat Immunol
, vol.2
, pp. 947-950
-
-
Schnare, M.1
Barton, G.M.2
Holt, A.C.3
Takeda, K.4
Akira, S.5
Medzhitov, R.6
-
165
-
-
0037121946
-
Lipopolysaccharide-enhanced, Toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen
-
Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K: Lipopolysaccharide-enhanced, Toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002;196:1645-1651.
-
(2002)
J Exp Med
, vol.196
, pp. 1645-1651
-
-
Eisenbarth, S.C.1
Piggott, D.A.2
Huleatt, J.W.3
Visintin, I.4
Herrick, C.A.5
Bottomly, K.6
-
166
-
-
0036569813
-
Toll-like receptor 4 is required for optimal development of Th2 immune responses: Role of dendritic cells
-
Dabbagh K, Dahl ME, Stepick-Biek P, Lewis DB: Toll-like receptor 4 is required for optimal development of Th2 immune responses: Role of dendritic cells. J Immunol 2002;168:4524-4530.
-
(2002)
J Immunol
, vol.168
, pp. 4524-4530
-
-
Dabbagh, K.1
Dahl, M.E.2
Stepick-Biek, P.3
Lewis, D.B.4
-
167
-
-
0036312668
-
Endotoxin can induce MyD88-deficient dendritic cells to support T(h)2 cell differentiation
-
Kaisho T, Hoshino K, Iwabe T, Takeuchi O, Yasui T, Akira S: Endotoxin can induce MyD88-deficient dendritic cells to support T(h)2 cell differentiation. Int Immunol 2002;14:695-700.
-
(2002)
Int Immunol
, vol.14
, pp. 695-700
-
-
Kaisho, T.1
Hoshino, K.2
Iwabe, T.3
Takeuchi, O.4
Yasui, T.5
Akira, S.6
-
168
-
-
0036780681
-
Toll-like receptors as potential therapeutic targets for multiple diseases
-
Zuany-Amorim C, Hastewell J, Walker C: Toll-like receptors as potential therapeutic targets for multiple diseases. Nat Rev Drug Discov 2002;1:797-807.
-
(2002)
Nat Rev Drug Discov
, vol.1
, pp. 797-807
-
-
Zuany-Amorim, C.1
Hastewell, J.2
Walker, C.3
-
169
-
-
0036453247
-
Plant disease resistance: Commonality and novelty in multicellular innate immunity
-
Fluhr R, Kaplan-Levy RN: Plant disease resistance: Commonality and novelty in multicellular innate immunity. Curr Top Microbiol Immunol 2002;270:23-46.
-
(2002)
Curr Top Microbiol Immunol
, vol.270
, pp. 23-46
-
-
Fluhr, R.1
Kaplan-Levy, R.N.2
-
170
-
-
0034671803
-
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses
-
Wyllie DH, Kiss-Toth E, Visintin A, Smith SC, Boussouf S, Segal DM, Duff GW, Dower SK: Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses. J Immunol 2000;165:7125-7132.
-
(2000)
J Immunol
, vol.165
, pp. 7125-7132
-
-
Wyllie, D.H.1
Kiss-Toth, E.2
Visintin, A.3
Smith, S.C.4
Boussouf, S.5
Segal, D.M.6
Duff, G.W.7
Dower, S.K.8
-
171
-
-
0033592748
-
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
-
Underhill DM, Ozinsky A, Hajjar AM, Stevens A, Wilson CB, Bassetti M, Aderem A: The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens (see comments). Nature 1999;401:811-815.
-
(1999)
Nature
, vol.401
, pp. 811-815
-
-
Underhill, D.M.1
Ozinsky, A.2
Hajjar, A.M.3
Stevens, A.4
Wilson, C.B.5
Bassetti, M.6
Aderem, A.7
-
172
-
-
0034651729
-
Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide
-
Flo TH, Halaas O, Lien E, Ryan L, Teti G, Golenbock DT, Sundan A, Espevik T: Human toll-like receptor 2 mediates monocyte activation by Listeria monocytogenes, but not by group B streptococci or lipopolysaccharide. J Immunol 2000;164:2064-2069.
-
(2000)
J Immunol
, vol.164
, pp. 2064-2069
-
-
Flo, T.H.1
Halaas, O.2
Lien, E.3
Ryan, L.4
Teti, G.5
Golenbock, D.T.6
Sundan, A.7
Espevik, T.8
-
173
-
-
0034669910
-
Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection
-
Takeuchi O, Hoshino K, Akira S: Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection. J Immunol 2000;165:5392-5396.
-
(2000)
J Immunol
, vol.165
, pp. 5392-5396
-
-
Takeuchi, O.1
Hoshino, K.2
Akira, S.3
-
174
-
-
0036134858
-
Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi
-
Wooten RM, Ma Y, Yoder RA, Brown JP, Weis JH, Zachary JF, Kirschning CJ, Weis JJ: Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi. J Immunol 2002;168:348-355.
-
(2002)
J Immunol
, vol.168
, pp. 348-355
-
-
Wooten, R.M.1
Ma, Y.2
Yoder, R.A.3
Brown, J.P.4
Weis, J.H.5
Zachary, J.F.6
Kirschning, C.J.7
Weis, J.J.8
-
175
-
-
0033458799
-
Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
-
Underhill DM, Ozinsky A, Smith KD, Aderem A: Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci USA 1999;96:14459-14463.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 14459-14463
-
-
Underhill, D.M.1
Ozinsky, A.2
Smith, K.D.3
Aderem, A.4
-
176
-
-
0032716031
-
The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors
-
Means TK, Lien E, Yoshimura A, Wang S, Golenbock DT, Fenton MJ: The CD14 ligands lipoarabinomannan and lipopolysaccharide differ in their requirement for Toll-like receptors. J Immunol 1999;163:6748-6755.
-
(1999)
J Immunol
, vol.163
, pp. 6748-6755
-
-
Means, T.K.1
Lien, E.2
Yoshimura, A.3
Wang, S.4
Golenbock, D.T.5
Fenton, M.J.6
-
177
-
-
0034709599
-
Cytokine-inducing macromolecular glycolipids from Enterococcus hirae: Improved method for separation and analysis of its effects on cellular activation
-
Hashimoto M, Imamura Y, Morichika T, Arimoto K, Takeuchi O, Takeda K, Akira S, Aoyama K, Tamura T, Kotani S, Suda Y, Kusumoto S: Cytokine-inducing macromolecular glycolipids from Enterococcus hirae: Improved method for separation and analysis of its effects on cellular activation. Biochem Biophys Res Commun 2000;273:164-169.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 164-169
-
-
Hashimoto, M.1
Imamura, Y.2
Morichika, T.3
Arimoto, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
Aoyama, K.8
Tamura, T.9
Kotani, S.10
Suda, Y.11
Kusumoto, S.12
-
178
-
-
0034283666
-
Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids
-
Schroder NW, Opitz B, Lamping N, Michelsen KS, Zahringer U, Gobel UB, Schumann RR: Involvement of lipopolysaccharide binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids. J Immunol 2000;165:2683-2693.
-
(2000)
J Immunol
, vol.165
, pp. 2683-2693
-
-
Schroder, N.W.1
Opitz, B.2
Lamping, N.3
Michelsen, K.S.4
Zahringer, U.5
Gobel, U.B.6
Schumann, R.R.7
-
179
-
-
0034443265
-
Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of toll-like receptors
-
Tsuji S, Matsumoto M, Takeuchi O, Akira S, Azuma I, Hayashi A, Toyoshima K, Seya T: Maturation of human dendritic cells by cell wall skeleton of Mycobacterium bovis bacillus Calmette-Guerin: Involvement of toll-like receptors. Infect Immun 2000;68:6883-6890.
-
(2000)
Infect Immun
, vol.68
, pp. 6883-6890
-
-
Tsuji, S.1
Matsumoto, M.2
Takeuchi, O.3
Akira, S.4
Azuma, I.5
Hayashi, A.6
Toyoshima, K.7
Seya, T.8
-
180
-
-
0035087367
-
Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through toll-like receptor 2
-
Ingalls RR, Lien E, Golenbock DT: Membrane-associated proteins of a lipopolysaccharide-deficient mutant of Neisseria meningitidis activate the inflammatory response through toll-like receptor 2. Infect Immun 2001;69:2230-2236.
-
(2001)
Infect Immun
, vol.69
, pp. 2230-2236
-
-
Ingalls, R.R.1
Lien, E.2
Golenbock, D.T.3
-
181
-
-
0035170049
-
A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via Toll-like receptor (TLR) 2 but not via TLR4/MD2
-
Pridmore AC, Wyllie DH, Abdillahi F, Steeghs L, van Der LP, Dower SK, Read RC: A lipopolysaccharide-deficient mutant of Neisseria meningitidis elicits attenuated cytokine release by human macrophages and signals via Toll-like receptor (TLR) 2 but not via TLR4/MD2. J Infect Dis 2001;183:89-96.
-
(2001)
J Infect Dis
, vol.183
, pp. 89-96
-
-
Pridmore, A.C.1
Wyllie, D.H.2
Abdillahi, F.3
Steeghs, L.4
Van Der, L.P.5
Dower, S.K.6
Read, R.C.7
-
182
-
-
0035165287
-
Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin
-
Hajjar AM, O'Mahony DS, Ozinsky A, Underhill DM, Aderem A, Klebanoff SJ, Wilson CB: Cutting edge: Functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin. J Immunol 2001;166:15-19.
-
(2001)
J Immunol
, vol.166
, pp. 15-19
-
-
Hajjar, A.M.1
O'Mahony, D.S.2
Ozinsky, A.3
Underhill, D.M.4
Aderem, A.5
Klebanoff, S.J.6
Wilson, C.B.7
-
183
-
-
0034912422
-
Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by toll-like receptor 2
-
Sugawara S, Yang S, Iki K, Hatakeyama J, Tamai R, Takeuchi O, Akashi S, Espevik T, Akira S, Takada H: Monocytic cell activation by nonendotoxic glycoprotein from Prevotella intermedia ATCC 25611 is mediated by toll-like receptor 2. Infect Immun 2001;69:4951-4957.
-
(2001)
Infect Immun
, vol.69
, pp. 4951-4957
-
-
Sugawara, S.1
Yang, S.2
Iki, K.3
Hatakeyama, J.4
Tamai, R.5
Takeuchi, O.6
Akashi, S.7
Espevik, T.8
Akira, S.9
Takada, H.10
-
184
-
-
0035399862
-
Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
-
Campos MA, Almeida IC, Takeuchi O, Akira S, Valente EP, Procopio DO, Travassos LR, Smith JA, Golenbock DT, Gazzinelli RT: Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J Immunol 2001;167:416-423.
-
(2001)
J Immunol
, vol.167
, pp. 416-423
-
-
Campos, M.A.1
Almeida, I.C.2
Takeuchi, O.3
Akira, S.4
Valente, E.P.5
Procopio, D.O.6
Travassos, L.R.7
Smith, J.A.8
Golenbock, D.T.9
Gazzinelli, R.T.10
-
185
-
-
0034976848
-
Different Toll-like receptor agonists induce distinct macrophage responses
-
Jones BW, Means TK, Heldwein KA, Keen MA, Hill PJ, Belisle JT, Fenton MJ: Different Toll-like receptor agonists induce distinct macrophage responses. J Leukoc Biol 2001;69:1036-1044.
-
(2001)
J Leukoc Biol
, vol.69
, pp. 1036-1044
-
-
Jones, B.W.1
Means, T.K.2
Heldwein, K.A.3
Keen, M.A.4
Hill, P.J.5
Belisle, J.T.6
Fenton, M.J.7
-
186
-
-
0035903158
-
Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells
-
Vabulas RM, Ahmad-Nejad P, da Costa C, Miethke T, Kirschning CJ, Hacker H, Wagner H: Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells. J Biol Chem 2001;276:31332-31339.
-
(2001)
J Biol Chem
, vol.276
, pp. 31332-31339
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Da Costa, C.3
Miethke, T.4
Kirschning, C.J.5
Hacker, H.6
Wagner, H.7
-
187
-
-
0035877013
-
An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells
-
Li M, Carpio DF, Zheng Y, Bruzzo P, Singh V, Ouaaz F, Medzhitov RM, Beg AA: An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells. J Immunol 2001;166:7128-7135.
-
(2001)
J Immunol
, vol.166
, pp. 7128-7135
-
-
Li, M.1
Carpio, D.F.2
Zheng, Y.3
Bruzzo, P.4
Singh, V.5
Ouaaz, F.6
Medzhitov, R.M.7
Beg, A.A.8
-
188
-
-
0036340341
-
Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling
-
Bieback K, Lien E, Klagge IM, Avota E, Schneider-Schaulies J, Duprex WP, Wagner H, Kirschning CJ, Ter M, V, Schneider-Schaulies S: Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling. J Virol 2002;76:8729-8736.
-
(2002)
J Virol
, vol.76
, pp. 8729-8736
-
-
Bieback, K.1
Lien, E.2
Klagge, I.M.3
Avota, E.4
Schneider-Schaulies, J.5
Duprex, W.P.6
Wagner, H.7
Kirschning, C.J.8
Ter, M.V.9
Schneider-Schaulies, S.10
-
189
-
-
0036737780
-
Bacterial fimbriae activate human peripheral blood monocytes utilizing TLR2, CD14 and CD11a/CD18 as cellular receptors
-
Ogawa T, Asai Y, Hashimoto M, Uchida H: Bacterial fimbriae activate human peripheral blood monocytes utilizing TLR2, CD14 and CD11a/CD18 as cellular receptors. Eur J Immunol 2002;32:2543-2550.
-
(2002)
Eur J Immunol
, vol.32
, pp. 2543-2550
-
-
Ogawa, T.1
Asai, Y.2
Hashimoto, M.3
Uchida, H.4
-
190
-
-
0037144610
-
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers
-
Flo TH, Ryan L, Latz E, Takeuchi O, Monks BG, Lien E, Halaas O, Akira S, Skjak-Braek G, Golenbock DT, Espevik T: Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. J Biol Chem 2002;277:35489-35495.
-
(2002)
J Biol Chem
, vol.277
, pp. 35489-35495
-
-
Flo, T.H.1
Ryan, L.2
Latz, E.3
Takeuchi, O.4
Monks, B.G.5
Lien, E.6
Halaas, O.7
Akira, S.8
Skjak-Braek, G.9
Golenbock, D.T.10
Espevik, T.11
-
191
-
-
0037131427
-
Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus
-
Mambula SS, Sau K, Henneke P, Golenbock DT, Levitz SM: Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem 2002;277:39320-39326.
-
(2002)
J Biol Chem
, vol.277
, pp. 39320-39326
-
-
Mambula, S.S.1
Sau, K.2
Henneke, P.3
Golenbock, D.T.4
Levitz, S.M.5
-
192
-
-
0037152173
-
Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
-
Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, Aepfelbacher M, Heesemann J: Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression. J Exp Med 2002;196:1017-1024.
-
(2002)
J Exp Med
, vol.196
, pp. 1017-1024
-
-
Sing, A.1
Rost, D.2
Tvardovskaia, N.3
Roggenkamp, A.4
Wiedemann, A.5
Kirschning, C.J.6
Aepfelbacher, M.7
Heesemann, J.8
-
193
-
-
0035869553
-
Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses
-
Means TK, Jones BW, Schromm AB, Shurtleff BA, Smith JA, Keane J, Golenbock DT, Vogel SN, Fenton MJ: Differential effects of a Toll-like receptor antagonist on Mycobacterium tuberculosis-induced macrophage responses. J Immunol 2001;166:4074-4082.
-
(2001)
J Immunol
, vol.166
, pp. 4074-4082
-
-
Means, T.K.1
Jones, B.W.2
Schromm, A.B.3
Shurtleff, B.A.4
Smith, J.A.5
Keane, J.6
Golenbock, D.T.7
Vogel, S.N.8
Fenton, M.J.9
-
194
-
-
0034834474
-
Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol
-
Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K, Nishijima M: Involvement of TLR4/MD-2 complex in species-specific lipopolysaccharide-mimetic signal transduction by Taxol. J Endotoxin Res 2001;7:232-236.
-
(2001)
J Endotoxin Res
, vol.7
, pp. 232-236
-
-
Kawasaki, K.1
Akashi, S.2
Shimazu, R.3
Yoshida, T.4
Miyake, K.5
Nishijima, M.6
-
195
-
-
0034768425
-
Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus
-
Haynes LM, Moore DD, Kurt-Jones EA, Finberg RW, Anderson LJ, Tripp RA: Involvement of toll-like receptor 4 in innate immunity to respiratory syncytial virus. J Virol 2001;75:10730-10737.
-
(2001)
J Virol
, vol.75
, pp. 10730-10737
-
-
Haynes, L.M.1
Moore, D.D.2
Kurt-Jones, E.A.3
Finberg, R.W.4
Anderson, L.J.5
Tripp, R.A.6
-
196
-
-
0037065909
-
Inflammatory response after open heart surgery: Release of heat-shock protein 70 and signaling through toll-like receptor-4
-
Dybdahl B, Wahba A, Lien E, Flo TH, Waage A, Qureshi N, Sellevold OF, Espevik T, Sundan A: Inflammatory response after open heart surgery: Release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation 2002;105:685-690.
-
(2002)
Circulation
, vol.105
, pp. 685-690
-
-
Dybdahl, B.1
Wahba, A.2
Lien, E.3
Flo, T.H.4
Waage, A.5
Qureshi, N.6
Sellevold, O.F.7
Espevik, T.8
Sundan, A.9
-
197
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
Lee JY, Sohn KH, Rhee SH, Hwang D: Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 2001;276:16683-16689.
-
(2001)
J Biol Chem
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
198
-
-
0037449723
-
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2 and inhibits phagocytosis of apoptotic cells
-
Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL: Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2 and inhibits phagocytosis of apoptotic cells. J Biol Chem 2002;278:1561-1568.
-
(2002)
J Biol Chem
, vol.278
, pp. 1561-1568
-
-
Miller, Y.I.1
Viriyakosol, S.2
Binder, C.J.3
Feramisco, J.R.4
Kirkland, T.N.5
Witztum, J.L.6
-
199
-
-
0037094084
-
Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4
-
Johnson GB, Brunn GJ, Kodaira Y, Platt JL: Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4. J Immunol 2002;168:5233-5239.
-
(2002)
J Immunol
, vol.168
, pp. 5233-5239
-
-
Johnson, G.B.1
Brunn, G.J.2
Kodaira, Y.3
Platt, J.L.4
-
200
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with toll-like receptor 4
-
Rassa JC, Meyers JL, Zhang Y, Kudaravalli R, Ross SR: Murine retroviruses activate B cells via interaction with toll-like receptor 4. Proc Natl Acad Sci USA 2002;99:2281-2286.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2281-2286
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.3
Kudaravalli, R.4
Ross, S.R.5
-
201
-
-
0036918723
-
Differential recognition of structural details of bacterial lipopeptides by toll-like receptors
-
Morr M, Takeuchi O, Akira S, Simon MM, Muhlradt PF: Differential recognition of structural details of bacterial lipopeptides by toll-like receptors. Eur J Immunol 2002;32:3337-3347.
-
(2002)
Eur J Immunol
, vol.32
, pp. 3337-3347
-
-
Morr, M.1
Takeuchi, O.2
Akira, S.3
Simon, M.M.4
Muhlradt, P.F.5
-
202
-
-
0035477969
-
Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells
-
Takeshita F, Leifer CA, Gursel I, Ishii KJ, Takeshita S, Gursel M, Klinman DM: Cutting edge: Role of Toll-like receptor 9 in CpG DNA-induced activation of human cells. J Immunol 2001;167:3555-3558.
-
(2001)
J Immunol
, vol.167
, pp. 3555-3558
-
-
Takeshita, F.1
Leifer, C.A.2
Gursel, I.3
Ishii, K.J.4
Takeshita, S.5
Gursel, M.6
Klinman, D.M.7
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