Indirect induction of suppressor of cytokine signalling-1 in macrophages stimulated with bacterial lipopolysaccharide: Partial role of autocrine/paracrine interferon-α/β

Biochemical Journal

Volumn 349, Issue 1, 2000, Pages 99-104

  Crespo, Ana ^a,b   Filla, Michael B ^a   Russell, Stephen W ^a   Murphy, William J ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Cellular activation; Nitric oxide; Signal transduction; Tolerance suppression

Indexed keywords

ALPHA INTERFERON; BACTERIUM LIPOPOLYSACCHARIDE; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; MESSENGER RNA; NITRIC OXIDE; STAT1 PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DNA BINDING; IMMUNE RESPONSE; KINETICS; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TIME;

ANIMALS; BLOTTING, NORTHERN; BONE MARROW CELLS; CARRIER PROTEINS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; INTERFERON-ALPHA; INTERFERON-BETA; KINETICS; LIPOPOLYSACCHARIDES; MACROPHAGES; MALE; MICE; MICE, INBRED C3H; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TIME FACTORS;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0034234797     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3490099     Document Type: Article

References (40)

1. 1 Karima, R., Matsumoto, S., Higashi, H. and Matsushima, K. (1999) The molecular pathogenesis of endotoxic shock and organ failure. Mol. Med. Today 5, 123-132
2. 2 Berczi, I. (1998) Neurohormonal host defense in endotoxin shock. Ann. N.Y. Acad. Sci. 840, 787-802
3. 3 Tracey, K. J., Fong, Y., Hesse, D. G., Manogue, K. R., Lee, A. T., Kuo, G. C., Lowry, S. F. and Cerami, A. (1987) Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature (London) 330, 662-664
4. 4 LeMay, L. G., Otterness, I. G., Vander, A. J. and Kluger, M. J. (1990) In vivo evidence that the rise in plasma IL 6 following injection of a fever-inducing dose of LPS is mediated by IL 1β. Cytokine 2, 199-204
5. 5 Bucklin, S. E., Russell, S. W. and Morrison, D. C. (1994) Augmentation of anticytokine immunotherapy by combining neutralizing monoclonal antibodies to interferon-γ and the interferon-γ receptor: protection in endotoxin shock. J. Endotoxin Res. 1, 45-51
6. 6 Carvalho, G. L., Wakabayashi, G., Shimazu, M., Karahashi, T., Yoshida, M., Yamamoto, S., Matsushima, K., Mukaida, N., Clark, B. D., Takabayashi, T. et al. (1997) Anti-interleukin-8 monoclonal antibody reduces free radical production and improves hemodynamics and survival rate in endotoxic shock in rabbits. Surgery 122, 60-68
7. 7 Beeson, P. B. (1947) Tolerance to bacterial pyrogen. I. Factors influencing its development. J. Exp. Med. 86, 29-38
8. 8 Granowitz, E. V., Porat, R., Mier, J. W., Orencole, S. F., Kaplanski, G., Lynch, E. A., Ye, K., Vannier, E., Wolff, S. M. and Dinarello, C. A. (1993) Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans. J. Immunol. 151, 1637-1645
9. 9 Cavaillon, J.-M. (1995) The nonspecific nature of endotoxin tolerance. Trends Microbiol. 3, 320-324
10. 10 Virca, G. D., Kim, S. Y., Glaser, K. B. and Ulevitch, R. J. (1989) Lipopolysaccharide induces hyporesponsiveness to its own action in RAW 264.7 cells. J. Biol. Chem. 264, 21951-21956
11. 11 Haas, J. G., Meyer, N., Riethmüller, G. and Ziegler-Heitbrock, H. W. (1990) Inhibition of lipopolysaccharide-induced in vitro desensitization by interferon-γ. Eur. J. Immunol. 20, 1181-1184
12. 12 Severn, A., Xu, D., Doyle, J., Leal, L. M., O'Donnell, C. A., Brett, S. J., Moss, D. W. and Liew, F. Y. (1993) Pre-exposure of murine macrophages to lipopolysaccharide inhibits the induction of nitric oxide synthase and reduces leishmanicidal activity. Eur. J. Immunol. 23, 1711-1714
13. 13 Chang, C. C., McCormick, C. C., Lin, A. W., Dietert, R. R. and Sung, Y. J. (1996) Inhibition of nitric oxide synthase gene expression in vivo and in vitro by repeated doses of endotoxin. Am. J. Physiol. 271, G539-G548
14. 14 Blackwell, T. S., Blackwell, T. R. and Christman, J. W. (1997) Induction of endotoxin tolerance depletes nuclear factor-κB and suppresses its activation in rat alveolar macrophages. J. Leukocyte Biol. 62, 885-891
15. 15 Lepe-Zuniga, J. L. and Klostergaard, J. (1990) Tolerance to endotoxin in vitro: independent regulation of interleukin-1, tumor necrosis factor and interferon alpha production during in vitro differentiation of human monocytes. Lymphokine Res. 9, 309-319
16. 16 Lorsbach, R. B. and Russell, S. W. (1992) A specific sequence of stimulation is required to induce synthesis of the antimicrobial molecule nitric oxide by mouse macrophages. Infect. Immun. 60, 2133-2135
17. 17 Gonnella, P. A., Starr, S., Rodrick, M. L. and Wilmore, D. W. (1994) Induced hyporesponsiveness in rat Kupffer cells is not specific for lipopolysaccharide. Immunology 81, 402-406
18. 18 Li, M. H., Seatter, S. C., Manthei, R., Bubrick, M. and West, M. A. (1994) Macrophage endotoxin tolerance: effect of TNF or endotoxin pretreatment. J. Surg. Res. 57, 85-92
19. 19 Barber, S. A., Fultz, M. J., Salkowski, C. A. and Vogel, S. N. (1995) Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages. Infect. Immun 63, 601-608
20. 20 Nicholson, S. E. and Hilton, D. J. (1998) The SOCS proteins: a new family of negative regulators of signal transduction. J. Leukocyte Biol. 63, 665-668
21. 21 Leung, K.-P., Russell, S. W., LeBlanc, P. A. and Caballero, S. (1985) Heterogeneity among macrophages cultured from mouse bone marrow. Morphologic, cytochemical and flow cytometric analyses. Cell Tissue Res. 239, 693-701
22. 22 Pace, J. L., MacKay R. J. and Hayes, M. P. (1987) Suppressive effect of interferon-β on development of tumoricidal activity in mouse macrophages. J. Leukocyte Biol. 41, 257-263
23. 23 Gao, J., Morrison, D. C., Parmely, T. J., Russell, S. W. and Murphy, W. J. (1997) An interferon-γ-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-γ and lipopolysaccharide. J. Biol. Chem. 272, 1226-1230
24. 24 Gao, J. J., Filla, M. B., Fultz, M. J., Vogel, S. N., Russell, S. W. and Murphy, W. J. (1998) Autocrine/paracrine IFN-αβ mediates the lipopolysaccharide-induced activation of transcription factor Stat1α in mouse macrophages: pivotal role of Stat1α in induction of the inducible nitric oxide synthase gene. J. Immunol. 161, 4803-4810
25. 25 Murphy, W. J., Muroi, M., Zhang, C. X., Suzuki, T. and Russell, S. W. (1996) Both basal and enhancer κB elements are required for full induction of the mouse inducible nitric oxide synthase gene. J. Endotoxin Res. 3, 381-393
26. 26 Starr, R., Willson, T. A., Viney, E. M., Murray, L. J. L., Rayner, J. R., Jenkins, B. J., Gonda, T. J., Alexander, W. S., Metcalf, D., Nicola, N. A. and Hilton, D. J. (1997) A family of cytokine-inducible inhibitors of signalling. Nature (London) 387, 917-921
27. 27 Song, M. M. and Shuai, K. (1998) The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities. J. Biol. Chem. 273, 35056-35062
28. 28 Losman, J. A., Chen, X. P., Hilton, D. and Rothman, P. (1999) Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J. Immunol. 162, 3770-3774
29. 29 Zhang, X., Alley, E. W., Russell, S. W. and Morrison, D. C. (1994) Necessity and sufficiency of beta interferon for nitric oxide production in mouse peritoneal macrophages. Infect. Immun. 62, 33-40
30. 30 Fujihara, M., Ito, N, Pace, J. L., Watanabe, Y., Russell, S. W. and Suzuki, T. (1994) Role of endogenous interferon-β in lipopolysaccharide-triggered activation of the inducible nitric oxide synthase gene in a mouse macrophage cell line, J774. J. Biol. Chem. 269, 12773-12778
31. 31 Nose, M., Uzawa, A., Nomura, M., Ikarashi, Y., Nakata, Y., Akashi, M. and Suzuki, G. (1998) Control of endotoxin shock by the dried preparation of low virulent Streptococcus pyogenes OK-432. Cell. Immunol. 188, 97-104
32. 32 Labeta, M. O., Durieux, J. J., Spagnoli, G., Fernandez, N., Wijdenes, J. and Herrmann, R. (1993) CD14 and tolerance to lipopolysaccharide: biochemical and functional analysis. Immunology 80, 415-423
33. 33 Cavaillon, J.-M., Pitton, C. and Fitting, C. (1994) Endotoxin tolerance is not a LPS-specific phenomenon: partial mimicry with IL-1, IL-10 and TGFβJ. Endotoxin Res. 1, 21-29
34. 34 Fahmi, H. and Chaby, R. (1993) Selective refractoriness of macrophages to endotoxin-induced production of tumor necrosis factor, elicited by an autocrine mechanism. J. Leukocyte Biol. 53, 45-52
35. 35 Randow, F., Syrbe, U., Meisel, C., Krausch, D., Zuckermann, H., Platzer, C. and Volk, H.-D. (1995) Mechanism of endotoxin desensitizalion: involvement of interleukin 10 and transforming growth factor β. J. Exp. Med 181, 1887-1892
36. 36 Stoiber, D., Kovarik, P., Cohney, S., Johnston, J. A., Steinlein, P. and Decker, T. (1999) Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-γ. J. Immunol. 163, 2640-2647
37. 37 Bode, J. G., Nimmesgern, A., Schmitz, J., Schaper, F., Schmitt, M., Frisch, W., Häussinger, D., Heinrich, P. C. and Graeve, L. (1999) LPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett. 463, 365-370
38. 38 Dickensheets, H. L., Venkataraman, C., Schindler, U. and Donnelly, R. P. (1999) Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression. Proc. Natl. Acad. Sci. U.S.A. 96, 10800-10805
39. 39 Alexander, W. S., Starr, R., Fenner, J. E., Scott, C. L., Handman, E., Sprigg, N. S., Corbin, J. E., Cornish, A. L., Darwiche, R., Owczarek, C. M. et al. (1999) SOCS1 is a critical inhibitor of interferon γ signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell 98, 597-608
40. 40 Morrison, D. C. and Ryan, J. L. (1987) Endotoxins and disease mechanisms. Annu. Rev. Med. 38, 417-432